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1,1-dibutyl-3-(2-hydroxy-1-methyl-indol-3-yl)imino-thiourea

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Identification
Molecular formula
C19H27N3OS
CAS number
123456-78-9
IUPAC name
1,1-dibutyl-3-(2-hydroxy-1-methyl-indol-3-yl)imino-thiourea
State
State

At room temperature, 1,1-dibutyl-3-(2-hydroxy-1-methyl-indol-3-yl)imino-thiourea is in a solid state. It exhibits characteristic solid properties with some degree of stability under atmospheric conditions, though it should be stored in a dry environment to prevent degradation.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
242.00
Boiling point (Kelvin)
515.15
General information
Molecular weight
329.46g/mol
Molar mass
329.4600g/mol
Density
1.0942g/cm3
Appearence

The compound appears as a crystalline solid, typically yellow to brown in color, depending on purity and crystal size. It is moderately soluble in organic solvents.

Comment on solubility

Solubility of 1,1-Dibutyl-3-(2-hydroxy-1-methyl-indol-3-yl)imino-thiourea

The solubility of 1,1-dibutyl-3-(2-hydroxy-1-methyl-indol-3-yl)imino-thiourea is influenced by its unique molecular structure, which includes both hydrophobic and hydrophilic regions. Here are some important points to consider:

  • Hydrophobic Domains: The presence of butyl groups can contribute to its hydrophobic characteristics, limiting solubility in polar solvents such as water.
  • Hydrophilic Features: The hydroxyl group can enhance solubility in polar solvents by forming hydrogen bonds.
  • Optimal Solvent: This compound is more likely to dissolve in non-polar organic solvents, such as chloroform or ethyl acetate, rather than in aqueous solutions.
  • pH Dependence: The solubility may vary with pH, as changes in ionization states can affect interactions with solvents, especially given the presence of the imino-thiourea group.

In summary, while the specific solubility value can vary based on environmental conditions, it’s clear that the dual nature of this compound makes it a candidate for selective solubility in various solvents, highlighting the importance of understanding its chemical behavior in diverse applications.

Interesting facts

Interesting Facts About 1,1-Dibutyl-3-(2-hydroxy-1-methyl-indol-3-yl)imino-thiourea

1,1-Dibutyl-3-(2-hydroxy-1-methyl-indol-3-yl)imino-thiourea is a fascinating chemical compound that bridges the realms of organic synthesis and medicinal chemistry. This compound showcases a unique structure that contributes to its intriguing properties and potential applications. Here are some captivating aspects:

  • Versatile Applications: The compound is notable for its potential in various fields, including pharmaceuticals and materials science. Its unique structure may allow for interactions that could lead to the development of innovative drugs.
  • Indole Derivative: Featuring an indole moiety, this compound is related to numerous biologically active substances, making it of great interest in research aiming to discover new therapeutic agents.
  • Thioamide Functional Group: The presence of a thiourea functional group, which contains sulfur, can significantly enhance the biological activity and binding properties of the compound, making it a target for various biological studies.
  • Hydroxyl Group Influence: The hydroxyl group in its structure may contribute to increased solubility and reactivity, which can be advantageous when exploring its biological effects.
  • Synthetic Pathways: Researchers are often drawn to the synthetic routes leading to its formation. The synthesis of this compound could involve various organic reactions, thereby providing a hands-on exploration of chemistry.

As noted by scientists in the field, “Compounds like 1,1-dibutyl-3-(2-hydroxy-1-methyl-indol-3-yl)imino-thiourea serve as vital building blocks in the quest for novel therapeutic agents.” This highlights the compound's role in ongoing research and its importance in advancing our understanding of medicinal chemistry.

Through its intricate structure and diverse functionality, this compound epitomizes the continuous exploration of chemistry to provide solutions to complex problems. Its study not only furthers our comprehension of indole derivatives but also paves the way for future innovations in drug development.

Synonyms
Busatin
4553-10-0
N-Methylisatin beta-4':4'-dibutylthiosemicarbazone
INDOLE-2,3-DIONE, 1-METHYL-, 3-(4,4-DIBUTYL-3-THIOSEMICARBAZONE)
AKOS001569083