Skip to main content

Lisuride

ADVERTISEMENT
Identification
Molecular formula
C22H27N3O
CAS number
18016-80-3
IUPAC name
1,1-diethyl-3-(7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl)urea
State
State

Lisuride is a solid at room temperature, typically supplied in pure crystalline or powdered form for various pharmaceutical applications.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.00
Boiling point (Celsius)
585.15
Boiling point (Kelvin)
858.30
General information
Molecular weight
338.48g/mol
Molar mass
338.4440g/mol
Density
1.2678g/cm3
Appearence

Lisuride appears as white to off-white, crystalline powder. It is typically available in solid form, appearing as fine crystals or powder that can also appear slightly yellowish due to impurities or degradation.

Comment on solubility

Solubility of 1,1-diethyl-3-(7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl)urea

The solubility of this compound, with the molecular formula C22H27N3O, is an intriguing aspect worthy of exploration. As with many organic compounds, solubility is influenced by various factors, including molecular structure, polarity, and the presence of functional groups. Here are some key points regarding its solubility:

  • Polarity: The molecule features both hydrophobic and hydrophilic regions due to its complex structure, which can affect how it interacts with solvents.
  • Solvents: Typically, such compounds may find better solubility in organic solvents (like ethanol or methanol) compared to water, primarily due to their larger nonpolar sections.
  • Temperature Effects: As is common with many chemical compounds, solubility may increase with temperature; therefore, heating the solution may enhance solubility.
  • Interactions with Solvents: The presence of the urea group suggests potential hydrogen bonding capabilities, which could allow for limited solubility in polar solvents under certain conditions.

In summary, while the solubility is not straightforward, it is expected that the compound exhibits varying degrees of solubility depending on the solvent type and temperature. As such, it can be said that understanding the solubility is a vital step in predicting behavior in experimental conditions.

Interesting facts

Interesting Facts about 1,1-Diethyl-3-(7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl)urea

This compound is a fascinating example of a complex organic structure that exemplifies the beautiful diversity found in the realm of chemical compounds. Here are some interesting aspects:

  • Unique Structure: The compound incorporates an indole framework, known for its presence in many natural products and biological activities. Indoles often serve as the core structure in medicinally useful compounds.
  • Pharmacological Potential: Compounds like this one are often investigated for their biological activity. Indol derivatives have been associated with numerous pharmacological properties, including anti-cancer, anti-inflammatory, and antimicrobial effects.
  • Synthetic Importance: The synthesis of this compound may involve multiple steps, highlighting the intricate strategies chemists develop to construct complex molecules in the lab. Creating compounds with such detailed geometry and specific substituents is a true testament to synthetic organic chemistry.
  • Research Applications: Due to its structural features, this compound is likely explored in research related to medicinal chemistry, possibly contributing to the development of novel therapeutic agents.
  • Complexity in Design: The specific functional groups present indicate a design led by the goal of achieving particular interactions, whether by modifying solubility or targeting specific biological pathways.

In summary, 1,1-diethyl-3-(7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl)urea is a compound that embodies the intersection of organic chemistry, pharmacology, and therapeutic discovery, making it an exciting subject for further exploration.

Synonyms
Tergurid; Terguride; trans-Dihydrolisuride
DTXSID80860548
HMS3371D09
N,N-Diethyl-N'-(6-methylergolin-8-yl)urea
L000794
S(+)-N,N-DIETHYL-N\'([8ALPHA]-6-METHYLERGOLIN-8-YL)UREA
3,3-diethyl-1-{6-methyl-6,11-diazatetracyclo[7.6.1.0(2),?.0(1)(2),(1)?]hexadeca-1(16),9,12,14-tetraen-4-yl}urea