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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4S
CAS number
59-87-0
IUPAC name
1,1-dimethyl-3-[(5-nitro-2-furyl)methyleneamino]isothiourea
State
State

Nitrofurazone is typically found in a solid state at room temperature. It is stable under normal temperatures and pressures but should be stored in a tightly closed container away from incompatible substances.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
374.00
Boiling point (Kelvin)
647.15
General information
Molecular weight
199.20g/mol
Molar mass
199.1670g/mol
Density
1.6740g/cm3
Appearence

Nitrofurazone appears as a yellow crystalline powder. It is often sold in various formulations for use in wound care and is applied directly to affected areas. The bright yellow coloration is characteristic of many nitrofuran compounds.

Comment on solubility

Solubility of 1,1-Dimethyl-3-[(5-nitro-2-furyl)methyleneamino]isothiourea

The solubility of 1,1-dimethyl-3-[(5-nitro-2-furyl)methyleneamino]isothiourea, a compound with complex functional groups, can be influenced by various factors. Understanding its solubility is crucial for applications in organic synthesis and pharmacology.

  • Generally, the presence of the isothiourea functional group can contribute to limited solubility in non-polar solvents due to hydrogen bond interactions.
  • The 5-nitro-2-furyl moiety introduces a polar characteristic which may enhance solubility in polar solvents, particularly in water and alcohols.
  • Yields may vary depending on the solvent system used; for instance, dimethyl sulfoxide (DMSO) is often employed to dissolve such complexes.

Research indicates that solubility is a critical parameter for determining the bioavailability of this compound in biological systems. In many cases, compounds with more polar or ionizable groups tend to exhibit better solubility, enhancing their potential therapeutic applications.

In summary, the solubility of 1,1-dimethyl-3-[(5-nitro-2-furyl)methyleneamino]isothiourea is likely to be moderate in polar solvents, while it may present challenges in non-polar environments. Thus, thorough analysis and appropriate solvent selection are essential for effective utilization in chemical processes.

Interesting facts

Interesting Facts about 1,1-Dimethyl-3-[(5-nitro-2-furyl)methyleneamino]isothiourea

This intriguing compound, 1,1-dimethyl-3-[(5-nitro-2-furyl)methyleneamino]isothiourea, showcases a fascinating interplay of structural features and functional groups. Known for its potential biological applications, it has caught the attention of researchers in various fields. Here are some compelling points about this compound:

  • Unique Structure: The presence of the isothiourea moiety distinguishes it from other thioureas, contributing to its unique reactivity and biological properties.
  • Biological Activity: Compounds featuring furan derivatives, such as the 5-nitro-2-furyl group, are often investigated for their antimicrobial and antitumor activities, making this compound a potential candidate for pharmaceutical research.
  • Synthetic Versatility: The synthesis of this compound typically involves a series of straightforward steps, making it an interesting target for synthetic chemists looking to explore new reagents and intermediates.
  • Research Potential: Studies have shown that compounds similar to this one can interact with various biological pathways. This opens avenues for the investigation of its mechanism of action.
  • Educational Value: For chemistry students, this compound serves as an excellent example of how small modifications to a molecular structure can lead to significantly different biological behavior and properties.

In summary, 1,1-dimethyl-3-[(5-nitro-2-furyl)methyleneamino]isothiourea not only presents a captivating study in molecular design but also stands as a potential key player in developing therapies against various diseases. Its multifaceted characteristics invite ongoing exploration and innovation in the scientific community.