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Dicyclomine Methyl Sulfate

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Identification
Molecular formula
C19H22NO2.CH3OSO3
CAS number
640-41-9
IUPAC name
(1,1-dimethylpiperidin-1-ium-2-yl)methyl 2-hydroxy-2,2-diphenyl-acetate;methyl sulfate
State
State

At room temperature, dicyclomine methyl sulfate is typically in a solid state.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
306.00
Boiling point (Kelvin)
579.15
General information
Molecular weight
387.49g/mol
Molar mass
387.4930g/mol
Density
1.3200g/cm3
Appearence

Dicyclomine methyl sulfate typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of (1,1-dimethylpiperidin-1-ium-2-yl)methyl 2-hydroxy-2,2-diphenyl-acetate; methyl sulfate

The solubility of a compound can provide vital insights into its behavior in various environments. In the case of (1,1-dimethylpiperidin-1-ium-2-yl)methyl 2-hydroxy-2,2-diphenyl-acetate; methyl sulfate, several key points define its solubility characteristics:

  • Aqueous Solubility: The presence of the piperidinium ion likely contributes to its solubility in water due to its ionic nature.
  • Hydroxy Group Influence: The hydroxy group (-OH) is known to enhance solubility in polar solvents, suggesting increased interaction with water molecules.
  • Effect of Alkyl Chains: The bulky diphenyl groups may hinder solubility slightly, depending on their spatial arrangement and the solvent used.
  • Temperature Sensitivity: Solubility can also vary with temperature; generally, increased temperatures lead to higher solubility for many organic compounds.

In summary, while the precise solubility profile may vary based on conditions, it is reasonable to anticipate that this compound exhibits better solubility in polar solvents like water, primarily due to its ionic and polar functional groups. As with many compounds, it exemplifies the principle that "like dissolves like," emphasizing the role of functional groups in determining solubility behavior.

Interesting facts

Exploring (1,1-dimethylpiperidin-1-ium-2-yl)methyl 2-hydroxy-2,2-diphenyl-acetate; methyl sulfate

The compound known as (1,1-dimethylpiperidin-1-ium-2-yl)methyl 2-hydroxy-2,2-diphenyl-acetate; methyl sulfate encompasses a range of intriguing properties relevant to organic chemistry and medicinal applications. Here are some fascinating insights:

  • Ion Exchange Properties: The presence of the dimethylpiperidin-1-ium cation suggests this compound can participate actively in ion-exchange reactions, making it a valuable component in the development of ionic liquids.
  • Biological Activity: Compounds of this nature may exhibit a variety of biological activities, potentially serving as starting points for the synthesis of pharmaceuticals focused on neuromodulation and other therapeutic areas.
  • Structural Versatility: The 2-hydroxy-2,2-diphenyl-acetate moiety contributes to the structural diversity of this compound, allowing it to interact with diverse biological targets through hydrogen bonding and π-π interactions due to the presence of aromatic systems.
  • Applications in Synthesis: As a methyl sulfate derivative, this compound could be utilized as a methylation reagent in organic synthesis, facilitating the introduction of methyl groups into various substrates.

Students and researchers often remark on the richness of information encapsulated in molecular structures such as this one. As noted by a prominent chemist, “The complexity of a compound reveals volumes about its potential applications.” This compound stands as a testament to the depth and breadth of organic chemistry, highlighting the intricate balance between structure and function in chemical compounds.

Additionally, its ability to form salts can lead to various physicochemical properties beneficial for various applications in pharmaceuticals and material sciences. The versatility of this compound makes it an exciting subject for further study in both academic and industrial contexts.

Synonyms
Bevonium methyl sulfate
BEVONIUM METILSULFATE
5205-82-3
Bevonium methylsulfate
Bevonium methylsulphate
Metilsulfato de bevonio
Metilsulfate de bevonium
Piribenzil methyl sulfate
Bevonii metilsulfas
Bevonium metilsulphate
Piribenzil methylsulfate
CG-201
UWC15E373Z
DTXSID3046615
DTXCID1026615
CHEBI:31283
bevonio metilsolfato
RefChem:917122
A03AB13
226-001-8
Acabel
CG 201
Bevonium metilsulfate [INN]
5205-82-3 (methylsulfate)
Bevonium (methylsulfate)
Bevonium metilsulfate (INN)
Bevonium methylsulfate (JAN)
Acabel;CG 201;Piribenzil methosulfate; Piribenzil methyl sulfate
BEVONIUM METHYLSULFATE [JAN]
(1,1-dimethylpiperidin-1-ium-2-yl)methyl 2-hydroxy-2,2-diphenylacetate;methyl sulfate
2-((2-hydroxy-2,2-diphenylacetoxy)methyl)-1,1-dimethylpiperidin-1-ium methyl sulfate.
2-({[Hydroxy(diphenyl)acetyl]oxy}methyl)-N,N-dimethylpiperidinium methyl sulphate
Bevonii metilsulfas [INN-Latin]
NCGC00167423-01
EINECS 226-001-8
Metilsulfate de bevonium [INN-French]
Metilsulfato de bevonio [INN-Spanish]
UNII-UWC15E373Z
L-99
Bevoniummetilsulfat
Bevonium metilsulfate [INN:BAN]
2-(Hydroxymethyl)-1,1-dimethylpiperidinium methyl sulfate benzilate
alpha-Phenylmandelic acid N,N-dimethylpiperidinium-2-methyl ester methylsulfate
Piperidinium, 2-(hydroxymethyl)-1,1-dimethyl-, methyl sulfate, benzilate
Benzilic acid ester with 2-(hydroxymethyl)-1,1-dimethylpiperidinium methyl sulfate
Benzilsaeure-(N,N-dimethyl-2-hydroxymethyl-piperidinium)-ester-methylsulfat [German]
Ester d'acide benzilique et du 1-methylsulfate de 1,1-dimethyl-(2-hydroxymethyl)piperidinium
Ester del acido bencilico del 1,1-dimetil-2-oximetil-piperidinio-metilsulfato [Spanish]
Piperidinium, 2-(((hydroxydiphenylacetyl)oxy)methyl)-1,1-dimethyl-, methyl sulfate (salt)
SCHEMBL25016
PIRIBENZYL METHYLSULFATE
CHEMBL2106080
AXKJGGRSAVLXTE-UHFFFAOYSA-M
Tox21_112427
BEVONIUM METHYL SULFATE [MI]
BEVONIUM METILSULFATE [MART.]
AKOS030242366
Benzilsaeure-(N,N-dimethyl-2-hydroxymethyl-piperidinium)-ester-methylsulfat
BEVONIUM METILSULFATE [WHO-DD]
Ester del acido bencilico del 1,1-dimetil-2-oximetil-piperidinio-metilsulfato
Piperidinium, 2-hydroxymethyl-1,1-dimethyl-, methanesulfonate, benzilate
CAS-5205-82-3
NS00044060
D01532
Q27291306
2-(HYDROXYMETHYL)-1,1-DIMETHYLPIPERIDINIUM METHYLSULFATE, BENZILATE
PIPERIDINIUM, 2-(((2-HYDROXY-2,2-DIPHENYLACETYL)OXY)METHYL)-1,1-DIMETHYL-, METHYL SULFATE (1:1)