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Orphenadrine citrate

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Identification
Molecular formula
C24H31NO3
CAS number
83-98-7
IUPAC name
(1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate
State
State

At room temperature, Orphenadrine citrate is generally in the form of a solid, specifically as a powder that is commonly used in pharmaceutical formulations.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.00
Boiling point (Celsius)
382.50
Boiling point (Kelvin)
655.70
General information
Molecular weight
461.52g/mol
Molar mass
461.5220g/mol
Density
1.1273g/cm3
Appearence

Orphenadrine citrate, when pure, typically appears as a white crystalline powder. It may also be found in a form that looks granular or as crystalline powder depending on the preparation method.

Comment on solubility

Solubility of (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate

When examining the solubility of the compound (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate (C24H31NO3), several intriguing aspects come into play:

  • Polarity: The presence of both a piperidinium cation and a diphenylacetate moiety suggests that the compound might exhibit a balance of hydrophilic and hydrophobic characteristics.
  • Solvent Interaction: Based on its structure, this compound is likely soluble in polar organic solvents such as methanol or ethanol due to hydrogen bonding opportunities from the hydroxyl group.
  • Insoluble in Water: However, due to the bulky diphenyl groups, the compound may be relatively insoluble in water, which is a sign of its lipophilic nature.

In summary, the solubility of this compound can be seen as a reflection of its complex structure, balancing interactions between polar and nonpolar regions. Understanding its solubility is crucial for applications in medicinal chemistry and materials science.

Interesting facts

Interesting Facts about (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate

(1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate is a fascinating compound with significant implications in various fields of chemistry and biochemistry. Below are some engaging insights into this unique chemical:

  • Structure and Stability: The presence of a piperidine ring gives this compound its unique chemical stability and reactivity. The quaternary ammonium ion enhances its solubility in polar solvents, which is advantageous for applications in drug formulation.
  • Biological Importance: Derivatives of piperidine are often studied for their potential therapeutic effects. This compound could potentially influence biological pathways, making it a subject of interest in medicinal chemistry.
  • Pharmacological Applications: Compounds like this one may act as ligands for neurotransmitter receptors or influence enzyme activity, showcasing their potential use in neuropharmacology.
  • Synthetic Versatility: The synthesis of this compound may involve innovative organic reactions, such as N-alkylation and esterification. Its complex structure serves as a scaffold for developing novel compounds in chemical research.
  • Research Potential: Ongoing studies could unveil new insights into its interaction mechanisms, particularly in the context of drug discovery and development.

In conclusion, the study of (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate not only deepens our understanding of piperidine derivatives but also opens new avenues in the fields of pharmacology and medicinal chemistry. As scientists continue to explore its properties, this compound holds promise for future advancements in therapeutic agents.

Synonyms
mepenzolate
Mepenzolic acid
Glycophenylate
25990-43-6
Mepenzolate ion
Mepenzolate cation
Cantril
Mepenzolon
ONW3LB39P7
(1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate
1-Methyl-3-piperidyl benzilate methyl bromide
Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-
UNII-ONW3LB39P7
PIPERIDINIUM, 3-((HYDROXYDIPHENYLACETYL)OXY)-1,1-DIMETHYL-
racemic mepenzolate
(plusmn)-mepenzolate
Piperidinium, 3-hydroxy-1,1-dimethyl-, benzilate (ester)
Spectrum_000985
Prestwick0_000653
Prestwick1_000653
Prestwick2_000653
Prestwick3_000653
Spectrum2_001042
Spectrum3_000490
Spectrum4_000042
Spectrum5_000948
MEPENZOLATE [VANDF]
BSPBio_000685
BSPBio_001959
KBioGR_000503
KBioSS_001465
MEPENZOLATE [WHO-DD]
DivK1c_000636
SPBio_000964
SPBio_002606
BPBio1_000755
CHEMBL524004
SCHEMBL2994933
DTXSID2046969
CHEBI:94411
GTPL10470
KBio1_000636
KBio2_001465
KBio2_004033
KBio2_006601
KBio3_001459
GKNPSSNBBWDAGH-UHFFFAOYSA-N
NINDS_000636
BDBM50377964
Piperidinium, 3-((hydroxydiphenylacetyl)oxy)-1,1-dimethyl- (VAN)
DB04843
IDI1_000636
NCGC00178896-01
NCGC00178896-02
SBI-0051436.P003
AB00053804
NS00015449
C07818
AB00053804_09
Q6817797
BRD-A62421304-004-05-6
BRD-A62421304-004-17-1
BRD-A62421304-004-18-9
(1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate
3-(2-HYDROXY(DIPHENYL)ACETOXY)-1,1-DIMETHYLPIPERIDINIUM
3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1,1-dimethylpiperidin-1-ium
2-hydroxy-2,2-diphenylacetic acid (1,1-dimethyl-3-piperidin-1-iumyl) ester