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Sulfonamide

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Identification
Molecular formula
C5H7NO2S
CAS number
127-65-1
IUPAC name
1,1-dioxothiolan-3-amine
State
State

At room temperature, sulfonamides are usually in the form of a solid, specifically as a crystalline powder. They are quite stable under ambient conditions.

Melting point (Celsius)
164.50
Melting point (Kelvin)
437.65
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
93.12g/mol
Molar mass
93.1200g/mol
Density
1.3000g/cm3
Appearence

Sulfonamides typically appear as solid substances, often as white to off-white crystalline or powder forms. They are generally colorless and odorless.

Comment on solubility

Solubility of 1,1-Dioxothiolan-3-amine

1,1-Dioxothiolan-3-amine is a unique chemical compound exhibiting intriguing solubility characteristics. When considering its solubility, several factors come into play:

  • Polarity: Due to its structural components, including the thiol and amine groups, the compound is relatively polar, which typically enhances its solubility in polar solvents.
  • Solvent Interaction: 1,1-Dioxothiolan-3-amine demonstrates notable solubility in water, as well as in alcohols and other polar solvents. This is primarily attributed to hydrogen bonding capabilities.
  • Temperature Dependence: As with many compounds, solubility can increase with temperature; thus, heating the solvent might improve the dissolution process.

However, it is essential to note that solubility can vary significantly based on specific conditions. Factors such as:

  • Purity: Impurities may impede solubility.
  • pH Levels: Variations in pH can affect the ionization state of the amine, further influencing solubility.

In summary, the solubility of 1,1-dioxothiolan-3-amine is quite favorable in polar solvents, making it a versatile compound for various applications. As with all compounds, understanding the environmental factors is crucial for optimizing its use.

Interesting facts

Interesting Facts About 1,1-Dioxothiolan-3-amine

1,1-Dioxothiolan-3-amine is a fascinating compound with a unique structure and noteworthy applications. As a derivative of thiolane, this compound features a five-membered ring with distinctive dioxo and amino functional groups. Here are some intriguing aspects to consider:

Unique Structural Characteristics

  • The presence of two carbonyl groups in the dioxo moiety gives this compound interesting reactivity, making it a valuable intermediary in organic synthesis.
  • The thiolane ring structure contributes to its chemical stability while allowing for diverse chemical manipulation, a characteristic highly prized in medicinal chemistry.

Applications in Research

  • This compound is being studied for its potential as a pharmaceutical precursor, where modifications can lead to the development of novel therapeutic agents.
  • Researchers are investigating its utility in the synthesis of other complex organic molecules, demonstrating its role in expanding the toolbox for synthetic chemists.

Potential Benefits and Uses

  • 1,1-Dioxothiolan-3-amine may act as a building block in the production of anti-cancer drugs due to its structural features that can interact with biological targets.
  • Its unique properties also make it a candidate for further study in the field of material science, where it might contribute to the development of new materials with specialized functionalities.

Overall, the study of 1,1-dioxothiolan-3-amine opens up a range of possibilities, merging creativity with scientific inquiry. As we uncover more about its properties and potential applications, this compound illustrates the dynamic and interconnected nature of chemical research.

Synonyms
6338-70-1
3-THIOPHENAMINE, TETRAHYDRO-, 1,1-DIOXIDE
3-Sulfolanylamine
N-3-Sulfolanylamine
Tetrahydro-3-thiophenamine 1,1-dioxide
EINECS 228-730-7
NSC 40793
BRN 3933935
DTXSID60884262
5-18-09-00474 (Beilstein Handbook Reference)
DTXCID60897312
1,1-dioxidotetrahydrothien-3-ylamine
3-Aminosulfolane
1,1-dioxothiolan-3-amine
3-Aminotetrahydrothiophene 1,1-dioxide
Tetrahydrothiophen-3-amine 1,1-dioxide
(1,1-Dioxidotetrahydro-3-thienyl)amine
3-amino-1lambda6-thiolane-1,1-dione
(1,1-dioxidotetrahydro-3-thienyl)amine hydrochloride
NSC40793
MFCD00022545
3-Aminotetrahydrothiophene1,1-dioxide
Oprea1_545192
SCHEMBL286216
(3R)-1,1-dioxothiolan-3-amine
ALBB-003927
BBL012872
NSC-40793
STK395034
1,1-dioxidotetrahydro-3-thienylamine
3-amino-1,1-dioxotetrahydrothiophene
1,1-dioxido-tetrahydrothien-3-ylamine
AKOS000200647
AKOS016039480
tetrahydro-1,1-dioxido-3-thienylamine
PB12042
1,1-dioxidotetrahydrothiophen-3-ylamine
(1,1-dioxotetrahydrothiophen-3-yl)amine
1,1-dioxo-tetrahydro-thiophen-3-ylamine
tetrahydrothiophene-3-amine 1,1-dioxide
BS-12820
PD207657
3-AMINO-1??-THIOLANE-1,1-DIONE
3-AMINO-1LAMBDA6-THIOLANE-11-DIONE
CS-0040471
NS00044795
EN300-33887
P10035
(+/-) 3-amino-tetrahydrothiophene 1,1-dioxide
1,1-dioxotetrahydro-1lambda6-thiophen-3-ylamine
F1294-0035
Tetrahydro-3-thiophenamine 1,1-dioxide, technical grade
1,1-DIOXO-TETRAHYDRO-1LAMBDA6-THIOPHEN-3-YLAMINE