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Tetracycline

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Identification
Molecular formula
C22H24N2O8
CAS number
60-54-8
IUPAC name
11-methoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one
State
State

Tetracycline is typically available in the form of a solid powder at room temperature. It is stable in a dry state but is moisture sensitive.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
824.00
Boiling point (Kelvin)
1 097.15
General information
Molecular weight
444.44g/mol
Molar mass
444.4350g/mol
Density
1.5800g/cm3
Appearence

Tetracycline appears as a yellow to light orange crystalline powder. It is hygroscopic and can darken upon exposure to light. It has a bitter taste.

Comment on solubility

Solubility of 11-methoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one

Understanding the solubility of complex compounds like 11-methoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one is a nuanced task. This compound demonstrates unique solubility characteristics that can be influenced by various factors:

  • Polarity: The presence of methoxy groups may enhance solubility in polar solvents, while the overall structure dictates its solubility in non-polar solvents.
  • Hydrogen Bonding: Functional groups capable of hydrogen bonding can improve interaction with solvent molecules, affecting solubility.
  • Temperature: Like many organic compounds, solubility often increases with temperature, allowing for more effective dissolution at elevated heat.

In general, this compound likely shows limited solubility in water due to its large and complex hydrophobic structure, which dominates the nature of its interactions with solvent molecules. As with many indole and quinoline derivatives, the solubility profile may vary significantly based on the solvent system employed. Researchers often note that:

"The solubility of a compound can be crucial for its application and efficacy, making it an essential parameter in chemical research and industry."

In summary: The solubility of 11-methoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one might be most favorable in organic solvents due to its complex structure, and requires careful study to fully ascertain its behavior in various environments.

Interesting facts

Interesting Facts about 11-methoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one

The compound discussed here is a striking member of the quinoline and indole family, characterized by its complex and diverse molecular structure. Here are some key insights:

  • Structural Complexity: This compound features multiple fused rings, which gives rise to a unique three-dimensional conformation that can be critical for its biological activity.
  • Applications in Medicinal Chemistry: Given its indole and quinoline components, researchers are investigating similar compounds for their potential therapeutic applications, particularly in treating cancer and other diseases.
  • Natural Product Inspiration: Many compounds in this group are found in various natural sources, including plants and fungi, showcasing the importance of nature in medicinal chemistry.
  • Synthetic Challenges: The synthesis of such a complex structure often involves multiple steps and intricate reactions. Mastery of organic synthesis techniques is crucial for anyone attempting to create similar compounds in the lab.
  • Mechanisms of Action: Understanding how such molecules interact with biological systems at the molecular level is essential for drug development. Researchers focus on how various substituents on the rings might influence receptor interactions and pharmacodynamics.

As a closing thought, it is essential to remember that compounds like this one stand at the intersection of synthetic chemistry and biological research, providing a fertile ground for discovery and innovation:

“Complexity is the hallmark of nature—embracing it leads to the future of chemistry.”