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Cortisol

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Identification
Molecular formula
C21H30O5
CAS number
50-23-7
IUPAC name
11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylene-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-one
State
State
Cortisol is typically found as a solid at room temperature. It is stable under normal conditions but can decompose when exposed to light or heat.
Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
650.00
Boiling point (Kelvin)
923.15
General information
Molecular weight
362.46g/mol
Molar mass
362.4600g/mol
Density
1.3100g/cm3
Appearence
Cortisol is a white to almost white crystalline powder. It is odorless and has a bitter taste. It may appear as a solid with a flaky or powdery texture.
Comment on solubility

Solubility of 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylene-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-one

The solubility of 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylene-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-one can vary significantly based on its molecular structure and functional groups. Understanding the solubility characteristics is crucial for applications in pharmaceuticals and other chemical industries.

Key Factors Influencing Solubility:

  • Polarity: This compound has both polar hydroxyl groups (-OH) and non-polar structural components. This combination can lead to varying solubility in polar and non-polar solvents.
  • Hydrogen Bonding: The presence of hydroxyl groups suggests that the molecule may participate in hydrogen bonding, enhancing its solubility in water or other polar solvents.
  • Temperature: Solubility often increases with temperature; thus, this compound may exhibit improved solubility at elevated temperatures.
  • Solvent Choice: It is essential to consider the solvent; for instance, organic solvents might dissolve the compound better due to its hydrophobic portions.

In summary, while the exact solubility data for this specific compound may require further empirical testing, the interplay of various factors like polarity, hydrogen bonding, and solvent characteristics provides a framework for predicting its solubility properties. Always remember that the specific conditions applied (e.g., temperature, pH) may influence the outcomes significantly. As expressed in chemical examinations, "the solubility of a compound is as complex as its structure." Therefore, careful methods should be employed to determine its solubility accurately.

Interesting facts

Interesting Facts about 11,17-Dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylene-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-one

This compound, often associated with the class of steroids, boasts a complex molecular architecture that intrigues chemists and biochemists alike. Here are some engaging points about it:

  • Biological Significance: Compounds similar to this one play critical roles in hormonal activities in the body. Many steroid-like substances are involved in regulating metabolism, immune response, and the development of sexual characteristics.
  • Structure Complexity: Its intricate structure incorporates multiple rings and functional groups, showcasing the diversity possible in organic chemistry. The presence of hydroxyl groups also suggests potential reactivity, allowing for a variety of chemical transformations.
  • Potential Applications: Due to its structure, this compound may have potential applications in pharmaceuticals, particularly in the development of new drugs focusing on hormone regulation and chemotherapy.
  • Synthetic Pathways: The synthesis of such complex molecules often challenges chemists to innovate. Understanding efficient synthetic routes can lead to advancements in organic synthesis techniques.
  • Research Opportunities: Ongoing research explores the interaction of this class of compounds with biological systems, opening doors to enhanced therapeutic strategies against diseases that are influenced by hormonal activity.

In essence, 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylene-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-one exemplifies the intersection of organic chemistry with biological significance, revealing the rich tapestry of interactions that characterize life.

Synonyms
SCHEMBL1650347
DTXSID80862269
NS00008901
11,17,21-Trihydroxy-16-methylidenepregna-1,4-diene-3,20-dione