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Tropisetron

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Identification
Molecular formula
C17H20N2O
CAS number
89565-68-4
IUPAC name
1,13-diethyl-10-methyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
State
State
Solid at room temperature, usually provided as a hydrochloride salt for medical use.
Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
316.50
Boiling point (Kelvin)
589.65
General information
Molecular weight
285.36g/mol
Molar mass
285.3780g/mol
Density
1.2350g/cm3
Appearence

Tropisetron is a crystalline solid that usually appears as a white or off-white powder. It is odorless and has a relatively high melting point, which is typical of many organic compounds within this class.

Comment on solubility

Solubility of 1,13-diethyl-10-methyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

The solubility of 1,13-diethyl-10-methyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol can be an intriguing aspect to consider, particularly given its complex molecular structure. Generally, the solubility of a compound can be influenced by several factors, including:

  • Polarity: Compounds with polar functional groups tend to be more soluble in polar solvents, such as water, whereas non-polar compounds are better dissolved in organic solvents.
  • Molecular Size: Larger molecules typically exhibit lower solubility due to steric hindrance, which can affect their ability to interact with solvent molecules.
  • Hydrogen Bonding: The presence of hydroxyl (–OH) groups can enhance solubility through hydrogen bonding with the solvent.

In the case of this specific compound, the presence of multiple ethyl groups and a hydroxyl group suggests moderate solubility in organic solvents, while its complex cyclic structure may limit solubility in water. It’s essential to carry out empirical testing to determine the exact solubility behavior firsthand. As the saying goes, “a substance is only as soluble as the solvent it is placed in.”

Thus, to summarize the solubility characteristics:

  • Likely to be soluble in organic solvents
  • Moderate solubility expected in polar solvents
  • Empirical data needed for precise characterization
Interesting facts

Interesting Facts about 1,13-Diethyl-10-methyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

The compound 1,13-diethyl-10-methyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol is a fascinating example of a complex organic molecule, showcasing the intricate nature of chemical structures. Here are some intriguing aspects of this compound:

  • Structure Complexity: This compound features a unique tricyclic arrangement, which is characterized by its three interconnected rings. Such configurations are often involved in producing notable biological activities.
  • Nitrogen Incorporation: The presence of an azatricyclo moiety (a nitrogen atom within a ring structure) highlights the important role of heteroatoms in influencing the chemical reactivity and biological properties of organic compounds.
  • Natural Product Inspiration: Many complex organic molecules, like this one, are inspired by or derived from natural products. Their intricate structures often serve as a foundation for drug design and development, especially in pharmacology.
  • Stereochemistry: The diverse configurations that arise from the multiple ethyl and methyl substituents can lead to different stereoisomers. This is essential in the context of biological systems, where the three-dimensional shape of a molecule can determine its activity.
  • Potential Applications: Compounds of this type may find applications in various fields including medicinal chemistry, materials science, and even agriculture, where understanding the interaction of complex organic molecules with biological systems can lead to innovative solutions.

"Complexity is the essence of beauty in organic chemistry." - Anonymous

In summary, 1,13-diethyl-10-methyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol serves as a remarkable illustration of the extraordinary possibilities that exist within organic synthesis. Understanding these compounds is not only crucial for advancing scientific knowledge but also for harnessing their potential in real-world applications.

Synonyms
27507-45-5
NIOSH/PB8615000
beta-(+-)-5,9-Diethyl-2'-hydroxy-2-methyl-6,7-benzomorphan
DTXSID50950187
PB86150000
alpha-(+-)-2'-Hydroxy-5,9-diethyl-2'-hydroxy-2-methyl-6,7-benzomorphan
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-diethyl-3-methyl-, alpha-(+-)-
6,11-Diethyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol
RefChem:1073539
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-diethyl-3-methyl-, beta-(+-)-
NCIOpen2_004475
cid_266438
CHEMBL3546162
BDBM94150
JYRBQCWXZNDERM-UHFFFAOYSA-N
DTXCID601378353
N-Methylpiperidino[2,4-b,c]1,2,3,4-tetrahydro-3,4-diethyl-6-hydroxynaphthalene