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Cyclazocine

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Identification
Molecular formula
C18H23NO
CAS number
294-90-6
IUPAC name
1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
State
State
Cyclazocine is a solid at room temperature, typically existing in a crystalline powder form.
Melting point (Celsius)
248.00
Melting point (Kelvin)
521.20
Boiling point (Celsius)
438.50
Boiling point (Kelvin)
711.70
General information
Molecular weight
299.39g/mol
Molar mass
299.4120g/mol
Density
1.2140g/cm3
Appearence

Cyclazocine is typically encountered as a white crystalline powder. It is often supplied in its hydrochloride salt form for enhanced stability and solubility in water.

Comment on solubility

Solubility of 1,13-Dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

The solubility of 1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol can be described considering several important factors:

  • Polarity: The compound contains both hydrophobic (aromatic) and hydrophilic (hydroxyl) groups, influencing its overall solubility in different solvents.
  • Solvent Interaction: It is likely to exhibit better solubility in organic solvents due to the presence of the aromatic ring, while the hydroxyl group can enhance solubility in polar solvents, though the complex structure may limit total solubility.
  • pH Effects: The solubility may also be pH-dependent due to the hydroxyl group, which can ionize in certain conditions, potentially increasing solubility.
  • Temperature Influence: As with many organic compounds, increased temperature may improve solubility, allowing for greater interaction with solvents.

Indeed, as with many compounds featuring complex cyclic structures, predicting solubility can be challenging. Experimentation is often required to accurately determine solubility characteristics in various solvents.

In summary, this compound exhibits unique solubility properties influenced by its structure, polarity, and the environment it is placed in. Understanding these factors is essential for effective application and utilization in further scientific explorations.

Interesting facts

Interesting Facts about 1,13-Dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

This compound, with its intricate name, represents a fascinating example of the diversity found in organic chemistry. As a member of the azabicyclic family, it exhibits unique structural features that have drawn the attention of researchers. Here are some compelling insights:

  • Diverse Applications: Compounds like this one often serve as key intermediates in drug synthesis. Their structural complexity can lead to the discovery of novel pharmaceuticals.
  • Structural Integrity: The rigidity of its tricyclic system allows for interesting conformational behavior, which may influence biological activity.
  • Phenylethyl Substitution: The presence of the two-carbon phenylethyl group enhances its lipophilicity, potentially influencing its interaction with biological membranes.
  • Research Opportunities: Scientists are actively exploring imitating natural products with similar structures, leading to breakthroughs in medicinal chemistry.
  • Chirality Considerations: This compound may have various stereoisomers, which can exhibit significantly different biological activities, making chirality a critical factor in its application.

In summary, 1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol is more than just a complex chemical formula; it is a doorway to understanding the intricate dance between molecular structure and function. As chemists continue to unravel its secrets, the potential for innovative applications in medicine and beyond remains vast. As stated by a prominent chemist, "The road from the laboratory to life-saving drugs is paved with intricate structures like this one."

Synonyms
PHENAZOCINE
Phenethylazocine
Fenazocina
Phenobenzorphan
127-35-5
Phenazocinum
Fenazocina [INN-Spanish]
Phenazocinum [INN-Latin]
NIH 7519
SKF 6574
Phenazocine [INN:BAN]
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(2-phenylethyl)-
1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-phenethyl-2,6-methano-3-benzazocin-8-ol
1,2,3,4,5,6-Hexahydro-8-hydroxy-6,11-dimethyl-3-phenethyl-2,6-methano-3-benzazocine
6,11-Dimethyl-1,2,3,4,5,6-hexahydro-8-hydroxy-3-phenethyl-2,6-methano-3-benzazocine
IDS-NP-008
DTXSID90860736
EINECS 204-835-3
Phenazocine [INN]
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-phenethyl-
Phenbenzorphan
2'-Hydroxy-5,9-dimethyl-2-phenethyl-6,7-benzomorphan
Fenazocina (INN-Spanish)
Phenazocinum (INN-Latin)
1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-phenylethyl)-2,6-methano-3-benzazocin-8-ol
Phenazocine [MI]
Phenazocine [WHO-DD]
J0ND6N0AQC
1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo(7.3.1.02,7)trideca-2(7),3,5-trien-4-ol
(+-)-ALPHA-PHENAZOCINE
DTXCID20197320
N02AD02
(+-)-.ALPHA.-PHENAZOCINE
58073-76-0
PHENAZOCINE CIS-(+-)-FORM
PHENAZOCINE CIS-(+-)-FORM [MI]
204-835-3
zqhykvknpwdqsl-uhfffaoysa-n
Prinadol
CHEMBL46399
DEA No. 9715
1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-phenylethyl)-2,6-methano-3-benzazocin-8-ol; 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-phenethyl-2,6-methano-3-benzazocin-8-ol; 2'-Hydroxy-5,9-dimethyl-2-phenethyl-6,7-benzomorphan; Phenethylazocine; Phenobenzorphan;
SCHEMBL26733
BDBM50027791
NS00041347
Q7181332
6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(phenazocine)