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Brimonidine hydrobromide

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Identification
Molecular formula
C11H10BrN5
CAS number
70359-46-5
IUPAC name
1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol;hydrobromide
State
State

This compound is typically a crystalline solid at room temperature and standard atmospheric conditions.

Melting point (Celsius)
260.20
Melting point (Kelvin)
533.35
Boiling point (Celsius)
292.80
Boiling point (Kelvin)
565.95
General information
Molecular weight
292.68g/mol
Molar mass
292.6700g/mol
Density
2.0071g/cm3
Appearence

Brimonidine hydrobromide appears as an off-white to pale yellow crystalline powder. It can sometimes appear in solid crystalline form and may exhibit polymorphism, meaning it can exist in more than one crystalline structure. It is commonly available in its pure form for pharmaceutical preparations.

Comment on solubility

Solubility of 1,13-Dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol; Hydrobromide

The solubility of 1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol; hydrobromide can be discussed based on several factors:

  • Solvent Compatibility: This compound is likely to exhibit variable solubility in polar and non-polar solvents, with a propensity to dissolve more readily in polar solvents due to its hydrobromide nature.
  • Temperature Influence: The solubility may increase with temperature, a common behavior observed in many organic compounds, allowing for greater molecular mobility and interactions.
  • pH Sensitivity: Given that this compound is a hydrobromide salt, its solubility might also be affected by the pH of the solution, where increased acidity may promote dissolution.
  • Hydrophobic Interactions: The presence of the phenylethyl group may introduce hydrophobic characteristics, potentially lowering solubility in highly polar solvents.

In conclusion, the solubility of 1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol; hydrobromide is influenced by a combination of its functional groups, solvent choice, temperature, and pH levels. This highlights the complex nature of solubility in organic compounds, which is vital for its applications in various chemical processes.

Interesting facts

Interesting Facts about 1,13-Dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol; Hydrobromide

This compound is a fascinating example of a complex organic molecule that showcases the intricate design of nature and the depth of synthetic chemistry. Here are some noteworthy aspects:

  • Structural Complexity: The name hints at a highly branched structure featuring multiple rings and functional groups, which makes this compound an interesting subject for chemists studying cyclization reactions and molecular architecture.
  • Bioactive Properties: Many compounds with such complex frameworks can exhibit pharmacological properties, prompting research into their potential as medicinal agents. The phenylethyl group suggests useful interactions in biological systems.
  • Research Implications: Understanding this compound could lead to insights in areas such as drug design and development, potentially influencing the synthesis of new therapeutic agents.
  • Hydrobromide Form: The hydrobromide salt form of this compound may enhance its stability and solubility in specific solvents, making it more accessible for laboratory studies.
  • Natural vs. Synthetic: While synthetic in nature, compounds with similar frameworks often occur in nature, allowing for comparisons that can bridge the gap between synthetic methodologies and natural product synthesis.

As chemists increasingly explore the depths of organic synthesis, compounds like this serve as both a challenge and a beacon for innovation. The statement, “In complexity lies beauty,” resonates well in the realm of chemical structures, where intricate designs can lead to groundbreaking discoveries.

Synonyms
1239-04-9
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(2-phenylethyl)-, hydrobromide (1:1)
PHENAZOCINE HYDROBROMIDE
6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,6-methanobenzo[d]azocin-8-ol hydrobromide
Phenazocine HBr
1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol;hydrobromide
PHENETHYLAZOCINE BROMIDE
Hydrobromide, Phenazocine
NIH-7519
SCHEMBL396395
CHEMBL2107297
DTXSID20872382
MNMGNPZLUMHSKK-UHFFFAOYSA-N
NS00081472
1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.0(2),]trideca-2(7),3,5-trien-4-ol hydrobromide
1,13-dimethyl-10-(2-phenylethyl)-10-azatricyclo[7.3.1.0,trideca-2(7),3,5-trien-4-ol hydrobromide