1,1,3-Trimethylisothiourea | Solubility of Things

Identification

Molecular formula

C₅H₁₂N₂S

CAS number

75507-68-9

IUPAC name

1,1,3-trimethylisothiourea

State

At room temperature, 1,1,3-Trimethylisothiourea is a solid substance. It is commonly found in a crystalline state, which allows for easy handling and processing in various chemical applications.

Melting point (Celsius)

99.00

Melting point (Kelvin)

372.15

Boiling point (Celsius)

191.00

Boiling point (Kelvin)

464.15

General information

Molecular weight

132.23g/mol

Molar mass

132.2280g/mol

Density

1.1585g/cm³

Appearence

1,1,3-Trimethylisothiourea typically appears as a white or off-white crystalline powder. It is often handled in a solid crystalline form, and care should be taken to store it properly to maintain its integrity.

Comment on solubility

Solubility of 1,1,3-Trimethylisothiourea

1,1,3-Trimethylisothiourea (C₄H₁₀N₂S) exhibits interesting solubility characteristics, largely influenced by its functional groups and molecular structure. Here are some key points regarding its solubility:

Polar Nature: The presence of both the thiourea group and multiple methyl groups leads to a polar molecular structure, which typically enhances solubility in polar solvents.
Water Solubility: 1,1,3-Trimethylisothiourea is generally soluble in water, making it suitable for various applications in aqueous environments.
Organic Solvents: It may also dissolve in some organic solvents, particularly those with polar characteristics, such as alcohols and certain ketones. However, non-polar solvents are unlikely to solubilize this compound effectively.

In summary, the solubility of 1,1,3-trimethylisothiourea can be described as favorable in polar environments, particularly due to its structural attributes. This property makes it a valuable compound in synthetic chemistry, where solubility plays a crucial role in reactivity and interaction.

Interesting facts

Interesting Facts about 1,1,3-Trimethylisothiourea

1,1,3-Trimethylisothiourea is a fascinating compound that belongs to the class of isothioureas, which are characterized by their unique structure and reactivity. Here are some intriguing aspects of this compound:

Structural Composition: The molecular structure of 1,1,3-trimethylisothiourea consists of a thiourea core with three methyl groups. This substitution enhances its solubility and reactivity.
Chemical Reactivity: It acts as a nucleophile, making it versatile in organic synthesis. It can participate in various reactions, including the formation of thiourea derivatives, which are significant in medicinal chemistry.
Biological Activity: Scientists are particularly interested in its biological properties. Some studies suggest potential antimicrobial and antifungal activities, showcasing its usefulness in pharmaceuticals.
Research Applications: 1,1,3-Trimethylisothiourea is often used as a reagent in chemical syntheses, which underscores its importance in academic and industrial research settings.
Sensitivity to Conditions: This compound can be sensitive to environmental conditions, which can affect its stability and reactivity. Understanding how different conditions influence its behavior is crucial for effective use.

In summary, 1,1,3-trimethylisothiourea is a compound with notable reactivity, potential biological applications, and significance in research. Its unique properties make it a subject of interest for chemists looking to explore new chemical syntheses and biological applications.