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1,1,3,3-Tetramethylthiourea

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Identification
Molecular formula
C5H12N2S
CAS number
632-22-4
IUPAC name
1,1,3,3-tetramethylthiourea
State
State

At room temperature, 1,1,3,3-tetramethylthiourea is typically a solid.

Melting point (Celsius)
75.00
Melting point (Kelvin)
348.15
Boiling point (Celsius)
219.50
Boiling point (Kelvin)
492.65
General information
Molecular weight
132.25g/mol
Molar mass
132.2450g/mol
Density
1.0663g/cm3
Appearence

1,1,3,3-Tetramethylthiourea appears as a white crystalline solid. Its structure allows it to participate in hydrogen bonding, affecting its physical properties.

Comment on solubility

Solubility of 1,1,3,3-Tetramethylthiourea

1,1,3,3-Tetramethylthiourea, often abbreviated as TMTU, is characterized by its interesting solubility properties. When discussing the solubility of this compound, several key points should be emphasized:

  • Polar Nature: The presence of both the thiourea group and multiple methyl groups confer moderate polarity to TMTU. This polarity affects its interaction with solvents.
  • Solubility in Water: TMTU is known to be soluble in water, making it favorable for applications in aqueous systems. Its ability to form hydrogen bonds enhances this solubility.
  • Solvents: In addition to water, TMTU exhibits good solubility in organic solvents, such as ethanol, methanol, and acetone, due to its non-polar methyl groups which facilitate solvation in these media.
  • Temperature Dependence: The solubility can be affected by temperature; typically, an increase in temperature will result in increased solubility for many compounds, including TMTU.

In summary, the solubility characteristics of 1,1,3,3-tetramethylthiourea make it a versatile compound in both aqueous and organic environments, being soluble in water and various common solvents. This enhances its applicability in different chemical processes and reactions.

Interesting facts

Interesting Facts About 1,1,3,3-Tetramethylthiourea

1,1,3,3-Tetramethylthiourea is a fascinating compound with unique properties and applications in various fields of chemistry. Here are some interesting facts about this intriguing molecule:

  • Structure: The molecular structure of 1,1,3,3-tetramethylthiourea features a thiourea group, where the nitrogen atom is bonded to the sulfur atom. This configuration contributes to its distinct chemical behavior.
  • Stabilizer: This compound serves as an excellent stabilizer for different organic reactions and is known for its ability to enhance the solubility of certain compounds, promoting efficient interaction within chemical processes.
  • Research Applications: 1,1,3,3-Tetramethylthiourea is often utilized in research to study and better understand substitution reactions in organic synthesis. Its reactivity makes it a subject of interest for chemists looking to develop new synthetic pathways.
  • Biological Relevance: Emerging studies have suggested that thiourea derivatives, including 1,1,3,3-tetramethylthiourea, may possess biological activities. Investigating these potential properties could lead to significant advancements in medicinal chemistry.
  • Safety First: While working with this compound, conducting safety assessments is essential. As with many chemical substances, proper laboratory practices should always be followed to ensure a safe working environment.

In summary, 1,1,3,3-tetramethylthiourea is more than just a chemical compound; it serves as a valuable tool in organic chemistry and has the potential for new discoveries. As chemists continue to explore its various properties and applications, we may unlock even more secrets of this versatile molecule.

Synonyms
TETRAMETHYLTHIOUREA
2782-91-4
1,1,3,3-Tetramethylthiourea
1,1,3,3-Tetramethyl-2-thiourea
Thiourea, tetramethyl-
Basthioryl
thiourea, N,N,N',N'-tetramethyl-
N,N,N',N'-Tetramethylthiourea
Urea, thio-, tetramethyl-
Tetramethyl-2-thiourea
NA-101
Urea, 1,1,3,3-tetramethyl-2-thio-
CCRIS 4871
NSC 102499
HSDB 6777
EINECS 220-488-0
BRN 1744916
AI3-28290
J6T67A1P72
NSC-102499
DTXSID5026126
TETRAMETHYLTHIOUREA [HSDB]
4-04-00-00232 (Beilstein Handbook Reference)
UREA,1,1,3,3-TETRAMETHYL,2-THIO
TETRAMETHYL-2-THIOUREA, 1,1,3,3-
Thiourea, tetramethyl
Urea, thio, tetramethyl
1,1,3,3Tetramethylthiourea
N,N,N',N'Tetramethylthiourea
1,1,3,3Tetramethyl2thiourea
DTXCID806126
N,N,N',N'-Tetramethyl thiourea
Thiourea, N,N,N',N'tetramethyl
Urea, 1,1,3,3tetramethyl2thio
NA101
inchi=1/c5h12n2s/c1-6(2)5(8)7(3)4/h1-4h
TMTU
tetramethyl thiourea
Tetramethyl-thiourea
MFCD00008324
UNII-J6T67A1P72
TMTU, 1,1,3,3-Tetramethyl-2-thiourea
Tetramethylthiourea, 98%
SCHEMBL15657
N,N',N'-Tetramethylthiourea
CHEMBL12214
SCHEMBL11104551
((CH3)2N)2CS
CHEBI:191168
Urea,1,3,3-tetramethyl-2-thio-
NSC102499
STK370053
AKOS005445484
FT33963
NCGC00341713-01
AS-12238
CS-0151338
NS00021983
EN300-42417
H10721
AB01334043-02
10.14272/MNOILHPDHOHILI-UHFFFAOYSA-N.1
doi:10.14272/MNOILHPDHOHILI-UHFFFAOYSA-N.1
Q22159079
F1285-1701