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Dihydroartemisinone

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Identification
Molecular formula
C13H16O1
CAS number
521-12-0
IUPAC name
1,1,4a-trimethyl-8,8a-dihydro-5H-naphthalen-2-one
State
State

At room temperature, Dihydroartemisinone is typically solid.

Melting point (Celsius)
76.50
Melting point (Kelvin)
349.65
Boiling point (Celsius)
282.30
Boiling point (Kelvin)
555.45
General information
Molecular weight
220.35g/mol
Molar mass
220.3510g/mol
Density
1.0300g/cm3
Appearence

Dihydroartemisinone typically appears as a white or off-white crystalline powder, often with a slightly bitter taste.

Comment on solubility

Solubility of 1,1,4a-trimethyl-8,8a-dihydro-5H-naphthalen-2-one

The compound 1,1,4a-trimethyl-8,8a-dihydro-5H-naphthalen-2-one exhibits some interesting characteristics when it comes to its solubility. Like many organic compounds with complex structures, its solubility is influenced by several factors:

  • Polarity: This compound is largely non-polar due to its naphthalene-like structure, which typically limits its solubility in polar solvents like water.
  • Solvent Compatibility: It is more likely to dissolve in non-polar solvents (e.g., hexane, toluene) due to similar interactions among the molecules.
  • Temperature Dependence: As with many organic compounds, solubility can increase with temperature, allowing for greater molecular motion and interactions in non-polar solvents.
  • Functional Groups: The presence of methyl groups affects its overall solubility behavior, potentially enhancing solubility in less polar environments.

In summary, while 1,1,4a-trimethyl-8,8a-dihydro-5H-naphthalen-2-one is expected to have limited solubility in aqueous conditions, it can readily dissolve in organic solvents. Its behavior exemplifies the classic adage, "like dissolves like," highlighting the importance of molecular structure in solubility outcomes.

Interesting facts

Interesting Facts about 1,1,4a-Trimethyl-8,8a-dihydro-5H-naphthalen-2-one

This unique compound, known for its intriguing structure, is commonly encountered in the field of organic chemistry. Here are some fascinating aspects of 1,1,4a-trimethyl-8,8a-dihydro-5H-naphthalen-2-one:

  • Structural Complexity: The compound features a naphthalene core, which is a fused ring system. This gives it a fascinating structural complexity that can influence its chemical behavior and reactivity.
  • Biological Interest: Compounds with similar naphthalene frameworks have been studied for their potential biological activities. They may exhibit properties that could be useful in medicinal chemistry.
  • Natural Occurrence: Some derivatives of naphthalene, like this compound, are found in various natural sources, including certain plant species. This can make them of interest for natural product chemistry.
  • Synthesis Routes: The synthesis of 1,1,4a-trimethyl-8,8a-dihydro-5H-naphthalen-2-one can involve multiple synthetic pathways, often requiring advanced organic chemistry techniques. Understanding these methods provides insights into complex chemical design.
  • Applications: Although specific applications may vary, compounds of this nature can be used in various industrial applications, including dyes, pharmaceuticals, and as intermediates in organic synthesis.

As a scientist or chemistry student, one might find themselves captivated by not only the structural attributes of this compound but also its potential applications in various fields. The exploration of such compounds enriches our understanding of organic chemistry, presenting intriguing avenues for research and discovery.

Synonyms
2(1H)-Naphthalenone, 4a,5,8,8a-tetrahydro-1,1,4a-trimethyl-, trans-
17429-27-5
DTXSID70938487
RHULEGWDLNKJIX-UHFFFAOYSA-N
1,1,4a-trimethyl-4a,5,8,8a-tetrahydronaphthalen-2(1H)-one
1,1,4a-Trimethyl-4a,5,8,8a-tetrahydro-2(1H)-naphthalenone #