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Doxorubicin hydrochloride

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Identification
Molecular formula
C27H30ClN1O11
CAS number
25316-40-9
IUPAC name
[(11S)-3-[amino(hydroxy)methylene]-4a,6,7,11,12-pentahydroxy-11-methyl-2,4,5-trioxo-1,11a,12,12a-tetrahydrotetracen-1-yl]-dimethyl-ammonium;chloride
State
State

Doxorubicin hydrochloride is typically in a solid state as a powder at room temperature. It is hygroscopic, meaning it can absorb moisture from the air. This property necessitates careful handling and storage to maintain its stability.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.20
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
579.99g/mol
Molar mass
579.9860g/mol
Density
1.5806g/cm3
Appearence
Doxorubicin hydrochloride appears as a red-orange powder. It is typically supplied as a lyophilized powder for reconstitution in water, and forms deep red solutions when dissolved.
Comment on solubility

Solubility of [(11S)-3-[amino(hydroxy)methylene]-4a,6,7,11,12-pentahydroxy-11-methyl-2,4,5-trioxo-1,11a,12,12a-tetrahydrotetracen-1-yl]-dimethyl-ammonium;chloride

The solubility of the compound [(11S)-3-[amino(hydroxy)methylene]-4a,6,7,11,12-pentahydroxy-11-methyl-2,4,5-trioxo-1,11a,12,12a-tetrahydrotetracen-1-yl]-dimethyl-ammonium;chloride is influenced by its unique structural characteristics. Specifically:

  • The presence of multiple hydroxyl (-OH) groups generally enhances solubility in polar solvents like water.
  • Dimethylammonium ions contribute to an increased interaction with water molecules, typically favoring solubility due to ion-dipole interactions.
  • Chloride ions usually indicate that the compound can dissolve in ionic solutions due to their ability to dissociate into aqueous environments.

However, the compound's complex configuration and molecular weight can lead to varying degrees of solubility:

  • High solubility might be observed in water due to ionic interactions.
  • Moderate to low solubility could occur in organic solvents, which may not effectively solvate the compound.

While the exact solubility can often be determined experimentally, the theoretical aspects provide a strong foundation for understanding its behavior in different solvents. In practical applications, it's essential to consider these factors when predicting the solubility of this compound.

Interesting facts

Interesting Facts about [(11S)-3-[amino(hydroxy)methylene]-4a,6,7,11,12-pentahydroxy-11-methyl-2,4,5-trioxo-1,11a,12,12a-tetrahydrotetracen-1-yl]-dimethyl-ammonium;chloride

The compound is a complex organic molecule with fascinating properties and applications. Here are some key points that illustrate its uniqueness:

  • Structural Diversity: With multiple hydroxyl groups and a trioxo structure, this compound showcases an incredible variety of functional groups that can engage in various chemical reactions.
  • Biological Relevance: Compounds with similar structural motifs often exhibit significant biological activity, making them potential candidates for pharmaceuticals or biomedical applications.
  • Ammonium Ion Influence: The presence of a dimethyl-ammonium group suggests that the compound can exhibit interesting ionic properties, which could influence its solubility and interaction with biological systems.
  • Chloride Counterion: The chloride component plays a crucial role in stabilizing the overall structure of the compound and may affect its compatibility in various chemical environments.
  • Potential for Research: Due to its complex structure and potential applications, this compound can serve as an excellent subject for further scientific exploration, particularly in drug design and synthetic organic chemistry.

Overall, the compound embodies the intricate balance of chemical functionality and potential for novel applications that can lead to groundbreaking discoveries in various fields.