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1,2-bis(2-methoxyphenyl)guanidine

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Identification
Molecular formula
C15H17N3O2
CAS number
66625-49-6
IUPAC name
1,2-bis(2-methoxyphenyl)guanidine
State
State

At room temperature, this compound is usually a solid.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.15
General information
Molecular weight
256.30g/mol
Molar mass
256.2990g/mol
Density
1.2100g/cm3
Appearence

1,2-bis(2-methoxyphenyl)guanidine typically appears as a crystalline solid. It may be white or have a faint coloration and should be handled in a dry environment to prevent any potential reactions with moisture.

Comment on solubility

Solubility of 1,2-bis(2-methoxyphenyl)guanidine

The solubility of 1,2-bis(2-methoxyphenyl)guanidine can be quite intriguing due to its unique structure and functional groups. In general, this compound demonstrates the following solubility characteristics:

  • Polar Solvents: It is known to have moderate solubility in polar solvents such as methanol and ethanol. The presence of methoxy groups lends some polarity to the molecule, which can interact favorably with these solvents.
  • Non-Polar Solvents: Conversely, its solubility in non-polar solvents like hexane or toluene is typically low. This is due to the hydrophobic nature of the aromatic rings present in its structure, which do not favor interaction with non-polar solvents.
  • pH Dependence: The solubility may also be affected by the pH of the solution. It's important to consider how guanidine derivatives can become protonated in acidic conditions, potentially altering solubility.

As a general observation, the solubility of 1,2-bis(2-methoxyphenyl)guanidine is dependent on several factors, including:

  1. Temperature: Increased temperature often enhances solubility.
  2. Concentration of the solvent: Higher concentrations of polar solvents can lead to better solubility.
  3. Presence of salts: Ionic strength can influence the solubility of organic compounds.

In summary, understanding the solubility of 1,2-bis(2-methoxyphenyl)guanidine provides valuable insights into its potential applications and behavior in various chemical environments. As always, comprehensive experimentation and evaluation are recommended for precise solubility data.

Interesting facts

Interesting Facts about 1,2-bis(2-methoxyphenyl)guanidine

1,2-bis(2-methoxyphenyl)guanidine is a fascinating compound in the realm of organic chemistry, particularly due to its unique structure and potential applications. Here are some intriguing insights about this compound:

  • Dual Functionality: The presence of two methoxyphenyl groups provides this compound with dual functionality, allowing it to exhibit diverse chemical properties.
  • Medicinal Potential: Research indicates that guanidine derivatives, like 1,2-bis(2-methoxyphenyl)guanidine, may possess interesting biological activities which could lead to the development of new pharmaceuticals.
  • Versatile Synthesis: This compound can be synthesized through various methods, making it a valuable target for synthetic chemists looking to explore different reaction pathways.
  • Study of Guanidine: Guanidine moieties are of particular interest in chemical research due to their ability to act as bases and nucleophiles, contributing to a variety of reactions.

In the words of a renowned chemist, “The beauty of organic chemistry lies not just in its compounds, but in the stories they tell and the transformations they undergo.”

This compound not only serves as a useful building block in chemical synthesis but also raises questions about its various interactions and potentials in different chemical environments.

As research progresses, the full extent of 1,2-bis(2-methoxyphenyl)guanidine's applications and properties will be unveiled, paving the way for innovations in both materials science and medicinal chemistry.

Synonyms
N,N'-Bis(2-methoxyphenyl)guanidine
Di-o-anisylguanidine
6268-03-7
I75KL19QFE
GUANIDINE, N,N'-BIS(2-METHOXYPHENYL)-
NSC 37143
NSC-37143
UNII-I75KL19QFE
BRN 3387288
DTXSID20211732
3-13-00-00812 (Beilstein Handbook Reference)
DTXCID50134223
CHEMBL310729
NSC37143
SCHEMBL2286441
BDBM50010745
N,N''-Bis-(2-methoxy-phenyl)-guanidine