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1,2-bis(o-tolyl)guanidine

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Identification
Molecular formula
C15H17N3
CAS number
97-39-2
IUPAC name
1,2-bis(o-tolyl)guanidine
State
State

At room temperature, 1,2-bis(o-tolyl)guanidine is a solid. It retains a crystalline structure, which is stable under standard conditions of temperature and pressure.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
454.00
Boiling point (Kelvin)
727.15
General information
Molecular weight
238.33g/mol
Molar mass
238.3250g/mol
Density
1.1542g/cm3
Appearence

1,2-Bis(o-tolyl)guanidine typically appears as a white to slightly off-white crystalline powder. It is known for its fine, crystalline form and can be expected to exhibit somewhat glossy surfaces due to its crystal structure.

Comment on solubility

Solubility of 1,2-bis(o-tolyl)guanidine

1,2-bis(o-tolyl)guanidine is an intriguing compound when it comes to its solubility characteristics. This guanidine derivative features two o-tolyl groups, which significantly influence its interaction with solvents.

Solubility in Various Solvents

The solubility of 1,2-bis(o-tolyl)guanidine can be described as follows:

  • Polar solvents: The compound shows limited solubility due to its relatively hydrophobic o-tolyl groups.
  • Non-polar solvents: It tends to dissolve more readily in non-polar organic solvents such as toluene or dichloromethane.
  • Water: It is generally considered to be insoluble or only sparingly soluble in water, reflecting the influence of its bulky aromatic groups.

This solubility profile highlights the significance of molecular structure in determining how 1,2-bis(o-tolyl)guanidine interacts with different solvents. As described in solubility theory, “like dissolves like,” emphasizing the importance of polarity in solubility behavior.

Key Points

  • Limited solubility in polar solvents.
  • Enhanced solubility in non-polar solvents.
  • Insoluble or sparingly soluble in water.

Understanding the solubility properties of 1,2-bis(o-tolyl)guanidine is essential for its application in various chemical processes, underscoring the intricate relationship between structure and solubility.

Interesting facts

Interesting Facts About 1,2-bis(o-tolyl)guanidine

1,2-bis(o-tolyl)guanidine is a fascinating compound that captures the attention of both chemists and researchers interested in its unique properties and applications. Here are some intriguing aspects of this compound:

  • Versatile Applications: This compound is primarily used as a chemical intermediate in the synthesis of various organic compounds. Its structural diversity allows it to serve multiple roles in the development of pharmaceuticals.
  • Coordination Chemistry: The guanidine moiety is known for its ability to coordinate with transition metals, making it valuable in catalytic processes and material science. This feature allows for the exploration of novel compounds with desired electronic and structural properties.
  • Toxicological Profile: As with many guanidine derivatives, 1,2-bis(o-tolyl)guanidine's biological activity has been studied. It is essential for chemists to understand both the benefits and potential risks associated with this compound in drug development.
  • Research and Innovation: Ongoing research focuses on modifying the structure of guanidine compounds to enhance their effectiveness in various applications. Scientists continue to uncover new aspects of 1,2-bis(o-tolyl)guanidine's reactivity and properties.
  • Synthetic Pathways: The typical synthetic routes to produce this compound highlight its significance in organic chemistry. Researchers often explore different methodologies to create analogs that could prove more effective for specific reactions.

Overall, 1,2-bis(o-tolyl)guanidine serves as an excellent example of how a single compound can embody multifaceted chemical dynamics, offering rich avenues for exploration. As noted by leading chemists, "The potential of guanidine derivatives in modern chemistry continues to inspire new research and innovation."

Synonyms
1,3-Di-o-tolylguanidine
97-39-2
ditolylguanidine
Di-o-tolylguanidine
DOTG
Vulkacite DOTG
Vulkacit DOTG
Eveite DOTG
Nocceler DT
Sanceler DT
Soxinol DT
Akrochem DOTG
Vulcafor DOTG
1,3-Ditolylguanidine
Diorthotolylguanidine
1,3-Bis(o-tolyl)guanidine
DTG
Vulkacit dotg/C
DOTG accelerator
N,N'-Di-o-tolylguanidine
1,3-Di-o-tolyguanidine
Guanidine, 1,3-di-o-tolyl-
Guanidine, N,N'-bis(2-methylphenyl)-
1,2-bis(2-methylphenyl)guanidine
USAF A-6598
NSC 473
CNS 1001
N,N'-Di-o-tolueylguanidine
N,N'-BIS(2-METHYLPHENYL)GUANIDINE
NSC 132023
HSDB 5307
Guanidine, 1,3-di(2-tolyl)-
1,3-Di-2-tolylguanidine
EINECS 202-577-6
BRN 2653884
LL2P01I17O
DTXSID2026606
AI3-14630
NSC-473
RHENOGRAN DOTG 70
NSC-132023
1,3-Di-o-tolylguanidine;DTG
DTXCID206606
NSC473
EC 202-577-6
MFCD00008513
Guanidine,3-di-o-tolyl-
N,N'-BIS(2-METHYLPHENYL)GUANIDINE [HSDB]
1,3-di-(2-tolyl)guanidine
WLN: 1R BMYUM & MR B1
Guanidine,N'-bis(2-methylphenyl)-
Diotolylguanidine
1,3-di-ortho-tolyl-guanidine
[3H]-di-o-tolylguanidine
[3H]DOTG
UNII-LL2P01I17O
Acrochem DOTG
Perkacit DOTG
Ekaland DOTG
Tol2Gdn
1,3-bis(2-methylphenyl)guanidine
Vanax DOTG
1,3Diotolyguanidine
1,3Ditolylguanidine
1,3Diotolylguanidine
N,N'Diotolylguanidine
N,N'Diotolueylguanidine
Tocris-0841
Guanidine, 1,3diotolyl
1,3Bis(otolyl)guanidine
N,N-Di-O-tolylguanidine
1,3-Di-o-tolylquanidine
N,N'-Di-o-toluylguanidine
cid_7333
Guanidine, 1,3di(2tolyl)
SCHEMBL35348
D.O.T.G
MLS001359937
1,2-di-(2-tolyl)guanidine
N,N'-Di-ortho-tolylguanidine
1,3-Bis(2-o-tolyl)guanidine
CHEMBL282433
GTPL6684
GTPL6685
BDBM81982
CHEBI:92585
1,3-Di-o-tolylguanidine, 99%
HMS3075A17
HMS3266J18
HMS3411P07
HMS3675P07
Guanidine, N,N'bis(2methylphenyl)
Tox21_200712
BDBM50009307
MSK001868
NSC132023
PDSP1_001846
PDSP2_001829
AKOS015840511
AKOS015916211
AKOS040758839
N,N'-Bis(2-methylphenyl)guanidine #
CAS-97-39-2
CAS_97-39-2
NCGC00024819-01
NCGC00024819-02
NCGC00248806-01
NCGC00258266-01
DA-72810
HY-14218
LS-14397
NCI60_004115
SMR001224330
MSK001868-100
1ST001868
CS-0002933
D0953
NS00008988
F71311
1ST001868-100
A858635
Q426022
SR-01000597454
SR-01000597454-1
BRD-K33459542-001-02-5
BRD-K33459542-001-07-4
Di-o-tolylguanidine Solution in Acetonitrile, 100?g/mL
Di-o-tolylguanidine Solution in Acetonitrile, 100mug/mL
202-577-6