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1,2-bis(trifluoromethyl)benzene

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Identification
Molecular formula
C8H4F6
CAS number
329-88-4
IUPAC name
1,2-bis(trifluoromethyl)benzene
State
State

At room temperature, 1,2-bis(trifluoromethyl)benzene is in a liquid state. It can be used as an intermediate in various chemical processes.

Melting point (Celsius)
-28.00
Melting point (Kelvin)
245.15
Boiling point (Celsius)
134.00
Boiling point (Kelvin)
407.15
General information
Molecular weight
212.12g/mol
Molar mass
212.1160g/mol
Density
1.4410g/cm3
Appearence

1,2-bis(trifluoromethyl)benzene is a clear, colorless liquid with a slight aromatic odor. The compound is often used in organic synthesis and other chemical applications.

Comment on solubility

Solubility of 1,2-bis(trifluoromethyl)benzene

1,2-bis(trifluoromethyl)benzene, commonly known as a derivative of fluorinated aromatic compounds, presents some intriguing solubility characteristics:

  • Nonpolar Nature: The presence of trifluoromethyl groups contributes to the overall nonpolar character of the molecule, which affects solubility in various solvents.
  • Solubility in Organic Solvents: It is typically soluble in nonpolar organic solvents such as benzene, toluene, and dichloromethane, due to similar nonpolar interactions.
  • Poor Water Solubility: Due to its nonpolar nature, 1,2-bis(trifluoromethyl)benzene exhibits very low solubility in water, making it challenging to dissolve in aqueous environments.
  • Influence of Temperature: The solubility may increase slightly with temperature, as is common for many organic compounds.

To summarize, the solubility of 1,2-bis(trifluoromethyl)benzene is predominantly in nonpolar solvents, and it is considered almost insoluble in water. This property is reflective of its structural characteristics and the interactions between its molecular constituents.

Interesting facts

Interesting Facts about 1,2-bis(trifluoromethyl)benzene

1,2-bis(trifluoromethyl)benzene, also known as diclofenac or 2,6-bis(trifluoromethyl)phenol, is a unique aromatic compound that exhibits remarkable properties due to its trifluoromethyl groups. Here are some engaging insights about this intriguing molecule:

  • Chemical Structure: The presence of trifluoromethyl groups significantly influences the electronic properties of the benzene ring, leading to enhanced reactivity and distinct chemical behavior.
  • Applications: This compound is extensively utilized in various fields, particularly in the synthesis of high-performance materials and pharmaceuticals. Its structural characteristics make it valuable in the design of potent drugs.
  • Fluorination: The introduction of fluorine atoms can modify a molecule’s physical, chemical, and biological properties, elevating the efficacy of active ingredients in medicinal chemistry.
  • Environmental Impact: Understanding the environmental behavior of compounds like 1,2-bis(trifluoromethyl)benzene is crucial, as fluorinated compounds can persist in the environment and may have implications for ecological safety.
  • Research Focus: Ongoing research is exploring its potential in the development of advanced materials, particularly in areas such as organic electronics and agrochemicals.

As a scientist or a chemistry student, it is significant to appreciate how such compounds, with their specialized functionalities, can play vital roles in modern science and technology. The study of compounds like 1,2-bis(trifluoromethyl)benzene not only enhances our understanding of chemical interactions but also aids in the advancement of innovative applications.

Synonyms
1,2-BIS(TRIFLUOROMETHYL)BENZENE
433-95-4
1,2-bis-(trifluoromethyl)benzene
MRD8XU7FGR
EINECS 207-092-3
Benzene, 1,2-bis(trifluoromethyl)-
o-Bis(trifluoromethyl)benzene
MFCD03094218
DTXSID90195818
o-Xylene, .alpha.,.alpha.,.alpha.,.alpha.',.alpha.',.alpha.'-hexafluoro-
hexafluoroxylene
UNII-MRD8XU7FGR
SCHEMBL63469
DTXCID30118309
BBL102779
STL556585
a,a,a,a',a',a'-Hexafluoro-o-xylene
AKOS005063710
GS-6818
26545-61-9
DB-051076
B3110
NS00042865
alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-o-xylene
InChI=1/C8H4F6/c9-7(10,11)5-3-1-2-4-6(5)8(12,13)14/h1-4
207-092-3