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DABCO lactam

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Identification
Molecular formula
C6H10N2O
CAS number
180-94-1
IUPAC name
1,2-diazabicyclo[2.2.2]octan-3-one
State
State

DABCO lactam is typically in a solid state at room temperature.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
315.20
Boiling point (Kelvin)
588.35
General information
Molecular weight
124.17g/mol
Molar mass
124.1720g/mol
Density
1.1298g/cm3
Appearence

DABCO lactam typically appears as a white crystalline solid. It is often found in powder form and is stable under standard temperature and pressure conditions.

Comment on solubility

Solubility of 1,2-diazabicyclo[2.2.2]octan-3-one

1,2-diazabicyclo[2.2.2]octan-3-one, often referred to by its systematic name, is a fascinating compound with specific solubility characteristics. Its solubility can be influenced by several factors:

  • Polarity: The presence of nitrogen atoms in the structure contributes to its polar characteristics, which often enhances its solubility in polar solvents.
  • Solvent Interactions: This compound tends to dissolve well in common polar solvents such as water, ethanol, and DMSO due to favorable interactions.
  • Temperature Effects: Generally, as temperature increases, the solubility of solids in liquids also tends to increase, which may apply to this compound.
  • pH Dependence: Given its functional groups, the solubility might also be influenced by the pH of the solution, particularly when engaging with acidic or basic environments.

In summary, while 1,2-diazabicyclo[2.2.2]octan-3-one is expected to be soluble in various polar solvents, its specific solubility can vary based on environmental conditions, such as temperature and pH. Understanding these factors can be essential for applications involving this intriguing compound.

Interesting facts

Interesting Facts About 1,2-Diazabicyclo[2.2.2]octan-3-one

1,2-Diazabicyclo[2.2.2]octan-3-one, commonly referred to as DBU (Diazabicyclo[2.2.2]octane), is a fascinating compound that has drawn attention in the fields of organic synthesis and catalysis. Here are some intriguing points about DBU:

  • Superbase Status: DBU is classified as a "superbase," meaning it has a higher basicity compared to standard bases like sodium hydroxide. Its unique structure allows it to deprotonate a wide variety of organic substrates effectively.
  • Versatile Catalyst: In the realm of organic chemistry, DBU is often employed as a catalyst in various reactions, including dehydration, alkylation, and acylation processes. This versatility makes it an invaluable tool for chemists.
  • Equilibrium Formation: The compound can exist in a tautomeric form, contributing to its reactive nature. The nitrogen atoms within the bicyclic framework play crucial roles in establishing the equilibrium between its various forms.
  • Applications in Medicine: Beyond organic synthesis, 1,2-Diazabicyclo[2.2.2]octan-3-one is being explored for its potential applications in medicinal chemistry, especially in the development of pharmaceuticals that require efficient synthesis pathways.

Scientists often highlight the phrase, "One molecule can change the course of a reaction," which encapsulates the significance of powerful compounds like DBU in advancing chemical research and applications. With its remarkable properties and roles in innovative reactions, 1,2-Diazabicyclo[2.2.2]octan-3-one continues to be a subject of study and admiration among chemists worldwide.

Synonyms
1,2-diazabicyclo[2.2.2]octan-3-one
1632-26-4
1,2-DIAZABICYCLO(2.2.2)OCTAN-3-ONE
2-Azaquinuclidone-3
3-oxo-2-azaquinuclidine
DTXSID60167527
NDZACTZHUWMHTA-UHFFFAOYSA-N
EN300-7633925
Z2181669941