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1,2-Dibenzylguanidine

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Identification
Molecular formula
C15H17N3
CAS number
140-56-7
IUPAC name
1,2-dibenzylguanidine
State
State

At room temperature, 1,2-Dibenzylguanidine is typically found in a solid state.

Melting point (Celsius)
149.00
Melting point (Kelvin)
422.15
Boiling point (Celsius)
385.00
Boiling point (Kelvin)
658.15
General information
Molecular weight
239.32g/mol
Molar mass
239.3290g/mol
Density
1.0495g/cm3
Appearence

1,2-Dibenzylguanidine typically appears as a white to off-white crystalline solid. Its appearance may vary slightly depending on the purity and specific form of the compound but generally maintains a consistent crystalline structure.

Comment on solubility

Solubility of 1,2-Dibenzylguanidine

1,2-Dibenzylguanidine, with its complex structure, exhibits intriguing solubility properties that can be dissected to understand its behavior in various solvents. This compound is a member of the guanidine family, known for their varied solubility characteristics.

Solubility Insights:

  • Solvent Dependency: 1,2-Dibenzylguanidine is more soluble in polar organic solvents. For instance, ethanol and dimethyl sulfoxide (DMSO) often provide favorable solubility owing to their ability to stabilize the compound's cationic forms.
  • Water Solubility: The solubility of this compound in water is relatively low, typically indicating a poor interaction with the polar solvent due to its large hydrophobic benzyl groups.
  • Temperature Influence: An increase in temperature may enhance solubility in organic solvents, thereby providing practical avenues for its usage in syntheses or reactions.

When considering the solubility of 1,2-dibenzylguanidine, it is essential to recognize that the balance between its hydrophobic and hydrophilic characteristics ultimately influences how it behaves in different environments. As with many organic compounds, tailored approaches to solvation can lead to interesting results and applications.

Interesting facts

Interesting Facts about 1,2-Dibenzylguanidine

1,2-Dibenzylguanidine is a fascinating compound that belongs to the class of guanidine derivatives. Here are some interesting aspects worth exploring:

  • Pharmacological Significance: This compound has been studied for its potential role in biomedical applications, particularly in the field of neuropharmacology. It has shown promise as a modulator of neurotransmitter systems.
  • Research Applications: Scientists have investigated its use in understanding neurological disorders, especially in the context of conditions such as depression and anxiety. Its influence on serotonin systems has made it a subject of interest.
  • Structure Activity Relationship (SAR): The unique structure of 1,2-dibenzylguanidine allows researchers to experiment with various chemical modifications. This aids in discovering how slight alterations can affect the compound's biological activity.
  • Multi-Functional Molecule: Beyond its effects on the brain, it may serve as a potential lead compound in the synthesis of novel pharmaceuticals, which can open avenues for new chemical entities with diverse functionalities.
  • Historical Context: The guanidine moiety has a rich history in organic chemistry and drug design, leading to the development of many important medicinal agents.

In summary, 1,2-dibenzylguanidine stands out as a compound with substantial implications for neuroscience and medicinal chemistry. Its intricate structure and bioactive properties make it a valuable subject of study for chemists and health scientists alike.

Synonyms
1,2-dibenzylguanidine
CHEMBL83430
25709-42-6
CHEMBL539782
n,n'-dibenzylguanidine
N,N'-Dibenzyl-guanidine
SCHEMBL1273847
SCHEMBL1275831
SCHEMBL1791607
SCHEMBL1795835
DTXSID70275021
BDBM50010774
N,N''-Dibenzyl-guanidine; hydrobromide