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(1,2-Dimethyl-3-phenylpyrrolidin-3-yl) propanoate

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Identification
Molecular formula
C15H21NO2
CAS number
13649-88-2
IUPAC name
(1,2-dimethyl-3-phenyl-pyrrolidin-3-yl) propanoate
State
State

At room temperature, (1,2-Dimethyl-3-phenylpyrrolidin-3-yl) propanoate is typically in a liquid state.

Melting point (Celsius)
25.00
Melting point (Kelvin)
298.15
Boiling point (Celsius)
238.50
Boiling point (Kelvin)
511.65
General information
Molecular weight
219.34g/mol
Molar mass
219.3100g/mol
Density
1.1150g/cm3
Appearence

The compound typically appears as a colorless to pale yellow liquid. Its appearance can vary depending on the level of purity and the specific conditions under which it is observed.

Comment on solubility

Solubility of (1,2-dimethyl-3-phenyl-pyrrolidin-3-yl) propanoate

The solubility of (1,2-dimethyl-3-phenyl-pyrrolidin-3-yl) propanoate can be influenced by various factors, including its molecular structure and polar/non-polar characteristics. Here are key aspects to consider:

  • Polarity: The presence of both hydrophobic (the alkyl and phenyl groups) and hydrophilic components (the propanoate group) plays a crucial role in solubility.
  • Solvent Interaction: This compound may dissolve well in organic solvents such as ethanol, methanol, and chloroform while showing limited solubility in water due to its bulky structure.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature, allowing for greater dispersion in non-polar and moderately polar solvents.
  • pH Influence: The acidity or basicity of the solution can alter the solubility of the propanoate moiety, especially in the presence of other ionic species.

In summary, while (1,2-dimethyl-3-phenyl-pyrrolidin-3-yl) propanoate is generally soluble in non-polar organic solvents, its solubility in polar solvents like water is expected to be low. Understanding these interactions can aid in predicting its behavior in various chemical environments.

Interesting facts

Interesting Facts about (1,2-dimethyl-3-phenyl-pyrrolidin-3-yl) propanoate

(1,2-dimethyl-3-phenyl-pyrrolidin-3-yl) propanoate, a compound featuring a complex structure, holds several intriguing aspects that make it notable in chemical and pharmacological contexts.

Key Characteristics

  • Structural Diversity: The compound consists of a pyrrolidine core, which is a five-membered ring containing nitrogen, highlighting the rich chemistry associated with cyclic amines.
  • Potential Biological Activity: Compounds related to pyrrolidinone derivatives often exhibit interesting pharmacological properties, including effects on neurotransmitter pathways, making them valuable in medicinal chemistry.
  • Versatile Syntheses: The synthesis of such esters often employs various methods, showcasing the ingenuity of synthetic organic chemistry. This can include reactions like nucleophilic substitution or esterification techniques.
  • Applications in Research: Its derivatives are sometimes studied for their activity as potential therapeutic agents, opening up lines of inquiry into how structural variations can affect biological activity.

Research Significance

In biochemical research, compounds like this one can serve as leads for the development of new pharmaceuticals. As noted by chemists, "changing a single bond within a complex molecule can lead to dramatically different biological effects." This emphasizes the importance of understanding molecular structure-function relationships.

Conclusion

With their rich structure and potential applications in pharmacology, compounds such as (1,2-dimethyl-3-phenyl-pyrrolidin-3-yl) propanoate highlight not only the complexities of organic chemistry but also the ongoing quest for discovering novel drug candidates. The study of such compounds ultimately contributes to advances in therapeutic options and highlights the fascinating interplay between chemistry and biology.

Synonyms
Prodilidine
Prodilidina
Prodilidine [INN]
Prodilidinum
3734-17-6
Prodilidinum [INN-Latin]
1,2-Dimethyl-3-phenyl-3-pyrrolidyl propionate
Prodilidina [INN-Spanish]
UNII-P67JPY18WD
P67JPY18WD
BRN 1431215
1,2-Dimethyl-3-phenyl-3-pyrrolidinol propionate (ester)
A-1981
CI-427
Propionic acid, 1,2-methyl-3-phenyl-3-pyrrolidinyl ester
DTXSID30863261
5-21-02-00386 (Beilstein Handbook Reference)
3-Pyrrolidinol, 1,2-dimethyl-3-phenyl-, propionate
Prodilidinum (INN-Latin)
Prodilidina (INN-Spanish)
DTXCID30811909
SCHEMBL26140
CHEMBL2110974
Q7247621