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1,2-Dimethyl-4-nitroimidazole

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Identification
Molecular formula
C5H7N3O2
CAS number
16402-37-4
IUPAC name
1,2-dimethyl-4-nitro-imidazole
State
State

At room temperature, 1,2-Dimethyl-4-nitroimidazole is a solid.

Melting point (Celsius)
70.00
Melting point (Kelvin)
343.15
Boiling point (Celsius)
284.00
Boiling point (Kelvin)
557.15
General information
Molecular weight
141.13g/mol
Molar mass
141.1340g/mol
Density
1.2970g/cm3
Appearence

1,2-Dimethyl-4-nitroimidazole typically appears as a crystalline solid. The color can vary depending on the purity, but it generally presents as a pale yellow to beige substance. It is usually handled as a powder for scientific and research purposes.

Comment on solubility

Solubility of 1,2-dimethyl-4-nitro-imidazole

1,2-dimethyl-4-nitro-imidazole, with the chemical formula C6H8N4O2, presents intriguing solubility characteristics influenced by its structural elements. Understanding its solubility is essential for applications in pharmacology and chemical synthesis.

Key Factors Affecting Solubility:

  • Polarity: The presence of the nitro group (-NO2) renders the compound more polar compared to non-polar imidazole derivatives, which generally enhances solubility in aqueous solutions.
  • Hydrogen Bonding: The ability of the nitrogen atoms to engage in hydrogen bonding can facilitate interactions with polar solvents, potentially improving solubility in organic solvents.
  • Alkyl Substituents: The methyl groups at the 1 and 2 positions provide some lipophilic character, influencing solubility in non-polar solvents.

Based on various solubility data, 1,2-dimethyl-4-nitro-imidazole is reported to be moderately soluble in water, which is notable for imidazole derivatives. However, it tends to exhibit higher solubility in organic solvents such as methanol and ethanol. As noted in several studies:

"Solubility is a critical property that influences the efficacy and bioavailability of a compound in pharmaceutical applications."

To summarize, the solubility of 1,2-dimethyl-4-nitro-imidazole can be categorized as follows:

  1. Moderate solubility in water
  2. High solubility in organic solvents

These properties underline the versatility of 1,2-dimethyl-4-nitro-imidazole for various chemical applications, emphasizing the need to consider solubility in both drug formulation and synthesis processes.

Interesting facts

Interesting Facts about 1,2-Dimethyl-4-nitro-imidazole

1,2-Dimethyl-4-nitro-imidazole is a fascinating compound with diverse applications in both scientific research and industrial processes. Here are some captivating aspects of this molecule:

  • Structural Diversity: The imidazole ring is a five-membered aromatic heterocycle containing two nitrogen atoms. This structural feature contributes to the compound's unique reactivity and properties.
  • Biological Significance: Compounds containing the imidazole core, such as this one, are often found in biologically active molecules. For instance, they play crucial roles in pharmaceuticals and natural products.
  • Potential Applications: 1,2-dimethyl-4-nitro-imidazole may have implications in the development of new drugs, particularly as a part of antibacterial or antifungal agents. Researchers continuously explore its potential for therapeutic uses.
  • Isomerism: This compound's position of substituents can lead to interesting isomers with different chemical behaviors and properties. Isomerism is a key concept in organic chemistry that helps explain why different compounds can exhibit vastly different effects.
  • Research Interest: Due to its nitro group, this compound has drawn interest in studies focused on nitro compounds, including their environmental impact and their reactivity in various chemical reactions.

In summary, 1,2-dimethyl-4-nitro-imidazole is a compelling example of the intricate relationships between chemical structure, biological activity, and potential applications in modern science. The exploration of such compounds not only aids in the pursuit of new materials but also enhances our understanding of fundamental chemical principles.

Synonyms
1,2-Dimethyl-4-nitro-1H-imidazole
13230-04-1
1,2-DIMETHYL-4-NITROIMIDAZOLE
1H-Imidazole, 1,2-dimethyl-4-nitro-
MFCD00139854
Imidazole, 1,2-dimethyl-4-nitro-
1,2-Dimethyl-4-nitro-imidazole
BRN 0121504
EINECS 236-201-7
SCHEMBL63286
DTXSID30157470
Imidazole, 4-nitro-1,2-dimethyl-
BBL028265
SBB025116
STK352059
AKOS005168008
AKOS015920675
SY387714
DB-011072
NS00024202
ST45123393
8E-023
EN300-231532