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Quinine methiodide

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Identification
Molecular formula
C20H25IN2
CAS number
132-58-9
IUPAC name
1,2-dimethyl-7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium;iodide
State
State

At room temperature, quinine methiodide is a solid. The compound is typically stable under standard conditions, making it well-suited for a variety of experimental and research applications.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
410.38g/mol
Molar mass
410.3830g/mol
Density
1.5200g/cm3
Appearence

Quinine methiodide appears as a crystalline solid, which is typically colorless to off-white in appearance. It may form needle-like crystals that are often utilized in laboratory settings for various studies and applications.

Comment on solubility

Solubility of 1,2-dimethyl-7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium;iodide

The solubility of 1,2-dimethyl-7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium;iodide can be influenced by several factors. Understanding its behavior in different solvents is crucial for its practical applications. Here are some key points regarding its solubility:

  • Polar vs. Non-Polar Solvents: Given its ionizable nature due to the presence of the iodide anion, this compound tends to exhibit better solubility in polar solvents such as water, methanol, or ethanol.
  • Temperature Dependency: Like many ionic compounds, its solubility will likely increase with temperature, allowing for enhanced dissolution rates and concentrations at elevated temperatures.
  • Concentration Effects: The ionic strength of the solution can also impact solubility. Introducing more electrolytes may create a shielding effect, possibly reducing the solubility of iodide due to the common ion effect.
  • pH Sensitivity: The compound's solubility may also change with pH levels, especially if it can participate in protonation or deprotonation reactions, further influencing its overall solubility in aqueous solutions.

As noted by researchers, "the solubility of cationic compounds often exceeds the limits when interacted with polar protic solvents," indicating that the choice of solvent is vital for maximizing solubility.

Ultimately, understanding the solubility characteristics of this compound is essential for its applications in various fields, including organic synthesis and medicinal chemistry.

Interesting facts

Interesting Facts about 1,2-Dimethyl-7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium; iodide

The compound 1,2-dimethyl-7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium; iodide is a fascinating entity within the realm of organic chemistry, primarily due to its unique structure and potential applications. Here are some intriguing aspects of this compound:

  • Structural Characteristics: This compound features a 1,2,3,4-tetrahydroisoquinoline backbone, which is a significant component in various biological molecules. The presence of two methyl groups and a phenyl substituent adds to the complexity and richness of its molecular architecture.
  • Biological Relevance: Isoquinoline derivatives, including this compound, are often studied for their potential pharmacological effects. They may exhibit properties such as antioxidant, antiviral, or even anticancer activities, making them vital in medicinal chemistry research.
  • Ion-Pairing Characteristics: As a quaternary ammonium salt due to the iodide component, this compound can form ion pairs, which can influence its chemical behavior and interactions in various settings.
  • Research and Synthesis: The synthesis of such complex molecules often involves innovative strategies in organic synthesis. Chemists can utilize reactions such as cyclization and functionalization approaches to construct the compound, often leading to the discovery of new synthetic methodologies.

The study of compounds like this opens up avenues for new discoveries in drug development and materials science, highlighting the importance of structure in determining functionality. As chemists continue to unravel the potential of these fascinating molecules, the relevance of structural diversity in chemical compounds becomes ever more apparent.

Synonyms
25297-77-2
ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-1,2-DIMETHYL-7-PHENYL-, HYDRIODIDE
RefChem:1087699
1,2-Dimethyl-7-phenyl-1,2,3,4-tetrahydroisoquinoline hydriodide