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1,2-Dimethylindole

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Identification
Molecular formula
C10H11N
CAS number
2385-06-6
IUPAC name
1,2-dimethylindole
State
State

At room temperature, 1,2-Dimethylindole is generally found in a solid state, often exhibiting a pale yellow color.

Melting point (Celsius)
33.00
Melting point (Kelvin)
306.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
145.20g/mol
Molar mass
145.1950g/mol
Density
1.0165g/cm3
Appearence

1,2-Dimethylindole typically appears as a pale yellow solid at room temperature. The coloration can vary slightly depending on purity and physical state, such as the presence of other forms or polymorphs.

Comment on solubility

Solubility of 1,2-Dimethylindole

1,2-Dimethylindole is an organic compound that displays interesting solubility characteristics. Its solubility can be influenced by various factors including polarity, temperature, and the presence of solvents. Below are some key points regarding its solubility:

  • Solvent Polarity: 1,2-Dimethylindole is generally soluble in organic solvents such as ethanol, chloroform, and acetone, owing to its non-polar hydrocarbon structure. This is typical for compounds in the indole family.
  • Water Solubility: The compound exhibits poor solubility in water, which can be attributed to its hydrophobic nature. The bulky methyl groups contribute to this characteristic.
  • Temperature Effects: Like many organic compounds, solubility can increase with temperature. As temperature rises, the kinetic energy of the molecules increases, potentially aiding solubilization.
  • Concentration Dependency: At higher concentrations, the solubility might reach a saturation point, where any excess of the compound would not dissolve further in the chosen solvent.

In summary, while 1,2-dimethylindole is not highly soluble in water, it shows much better solubility in various organic solvents, making it suitable for numerous chemical applications.

Interesting facts

Interesting Facts about 1,2-Dimethylindole

1,2-Dimethylindole is a fascinating compound that belongs to the indole family, which is a class of compounds known for their roles in biological processes and complex organic chemical structures. Here are some intriguing aspects of this compound:

  • Structural Characteristics: 1,2-Dimethylindole features a bicyclic structure, comprising a five-membered nitrogen-containing ring fused with a six-membered carbon ring. This unique dual-ring formation contributes to its diverse chemical behavior and reactivity.
  • Biological Significance: Indole derivatives, including 1,2-dimethylindole, are often implicated in vital biological processes. For instance, indole and its derivatives are precursors to various natural products such as the neurotransmitter serotonin, highlighting their importance in biochemistry.
  • Applications in Organic Synthesis: This compound serves as a versatile building block in organic synthesis. Chemists utilize 1,2-dimethylindole in the development of pharmaceuticals, agrochemicals, and other fine chemicals, demonstrating its utility in industrial applications.
  • Research Potential: Ongoing research in the fields of medicinal chemistry and agrochemistry frequently examines the properties and applications of indole derivatives like 1,2-dimethylindole, leading to exciting discoveries and innovations.

As a result, 1,2-dimethylindole stands out not just for its structural beauty but also for its valuable contributions to chemistry and biology. As the quote goes, "Chemistry is the study of transformation," and compounds like 1,2-dimethylindole exemplify this transformation in both natural and synthetic realms.

With its blend of structural complexity, biological importance, and practical applications, the study of 1,2-dimethylindole is sure to enhance our understanding of the chemical world and inspire future scientific exploration.

Synonyms
1,2-DIMETHYLINDOLE
875-79-6
1,2-Dimethyl-1H-indole
N-Methyl-2-methylindole
Indole, 1,2-dimethyl-
1H-Indole, 1,2-dimethyl-
H373TS720O
EINECS 212-877-9
NSC 62087
NSC-62087
DTXSID00236367
1,2dimethylindole
NMethyl2methylindole
Indole, 1,2dimethyl
1HIndole, 1,2dimethyl
Indole, 1,2dimethyl (8CI)
Indole, 1,2-dimethyl-(8CI)
1HIndole, 1,2dimethyl (9CI)
DTXCID00158858
1H-Indole, 1,2-dimethyl-(9CI)
212-877-9
MFCD00005802
1.2-Dimethylindole
1,2-dimethyl indole
UNII-H373TS720O
dimethyl-1H-indole
1H-Indole,2-dimethyl-
1,2-Dimethylindole, 99%
SCHEMBL154592
CHEMBL3252124
BJMUOUXGBFNLSN-UHFFFAOYSA-
NSC62087
STK301478
AKOS003791088
CS-W010998
SB14858
AC-28904
AS-14361
SY004658
D1391
NS00039205
EN300-136093
Q27279585
InChI=1/C10H11N/c1-8-7-9-5-3-4-6-10(9)11(8)2/h3-7H,1-2H3