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alpha-Pyrrolidinopropiophenone (alpha-PPP)

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Identification
Molecular formula
C17H21NO
CAS number
15379-82-7
IUPAC name
1,2-diphenyl-2-(1-piperidyl)ethanone
State
State

At room temperature, it exists as a solid crystalline substance. It is generally stable under normal conditions and requires appropriate storage to maintain its integrity.

Melting point (Celsius)
189.00
Melting point (Kelvin)
462.15
Boiling point (Celsius)
357.00
Boiling point (Kelvin)
630.15
General information
Molecular weight
251.35g/mol
Molar mass
251.3460g/mol
Density
0.9000g/cm3
Appearence

1,2-diphenyl-2-(1-piperidyl)ethanone appears as a white crystalline powder, though impurities or various sources may give it a slightly off-white or yellow tint. The compound typically forms well-defined crystals under suitable conditions.

Comment on solubility

Solubility of 1,2-diphenyl-2-(1-piperidyl)ethanone

The solubility of 1,2-diphenyl-2-(1-piperidyl)ethanone can be influenced by several factors, making it an interesting compound to consider in terms of its solubility characteristics. Here are some key points to note:

  • Solvent Type: This compound generally exhibits higher solubility in organic solvents such as ethanol and dichloromethane, as opposed to water.
  • Polarity: Due to its non-polar character, 1,2-diphenyl-2-(1-piperidyl)ethanone is less soluble in polar solvents.
  • Temperature Influence: The solubility tends to increase with a rise in temperature, which is typical for many organic compounds.
  • Hydrogen Bonding: The presence of the piperidine ring may contribute some capacity for hydrogen bonding, enhancing solubility in certain polar aprotic solvents.

In summary, while predicting solubility can be complex due to the influence of temperature, solvent compatibility, and molecular interactions, it can generally be stated that 1,2-diphenyl-2-(1-piperidyl)ethanone is more soluble in less polar organic solvents than in water. Understanding these solubility dynamics is crucial for applications in organic chemistry and pharmaceuticals.

Interesting facts

Interesting Facts about 1,2-Diphenyl-2-(1-piperidyl)ethanone

1,2-Diphenyl-2-(1-piperidyl)ethanone is a fascinating compound that belongs to the family of ketones, known for its diverse applications in medicinal chemistry and organic synthesis. Here are some key points that highlight its significance:

  • Structure and Function: This compound features a unique combination of a ketone moiety and a piperidine ring, which contributes to its biological activities. The piperidine group is particularly interesting because it often enhances the pharmacological properties of various compounds.
  • Pharmacological Potential: Research has indicated that derivatives of ketones like this one may exhibit antidepressant and anxiolytic effects, making them potential candidates for new medications. Studies in this area continue to explore how modifications to the structure can lead to improved therapeutic profiles.
  • Organic Synthesis: 1,2-Diphenyl-2-(1-piperidyl)ethanone serves as a versatile intermediate in organic synthesis. Its reactivity allows chemists to use it as a building block for creating other complex molecules, showcasing its importance in the development of new materials and drugs.
  • Chemical Properties: This compound's reactivity is notable, particularly in reactions involving nucleophiles. It can undergo various transformations that allow for the creation of diverse functional groups, enhancing its utility in the laboratory.
  • Inspirational Chemistry: The exploration of compounds like 1,2-diphenyl-2-(1-piperidyl)ethanone inspires chemists to develop innovative drugs and materials. The challenges presented by its molecular structure encourage creativity in synthetic pathways, making it an exciting subject for study.

In conclusion, the study of 1,2-diphenyl-2-(1-piperidyl)ethanone exemplifies the intricate relationship between chemistry and biology, paving the way for advancements in pharmaceuticals and synthetic methodologies. As research progresses, this compound may play a pivotal role in the discovery of new therapeutic agents.

Synonyms
SCHEMBL9366693
AKOS000505024
AKOS030483558