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Bryostatin 1

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Identification
Molecular formula
C47H68O17
CAS number
83314-01-6
IUPAC name
12-hydroxy-2-[(5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]-9-(3-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl)oxy-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione
State
State

At room temperature, Bryostatin 1 is typically in a solid state, often found as a powder.

Melting point (Celsius)
226.00
Melting point (Kelvin)
499.00
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.00
General information
Molecular weight
905.04g/mol
Molar mass
905.0390g/mol
Density
1.3400g/cm3
Appearence

Bryostatin 1 typically appears as an off-white to yellowish powder when purified.

Comment on solubility

Solubility of 12-hydroxy-2-[(5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]-9-(3-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl)oxy-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione

The solubility of complex organic compounds like 12-hydroxy-2-[(5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]-9-(3-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl)oxy-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione can often be influenced by various factors including structure, polarity, and the presence of functional groups. Here are some key points to consider:

  • Polarity: The significant number of hydroxyl (-OH) and methoxy (-OCH3) groups in this compound may enhance its solubility in polar solvents, such as water and alcohol.
  • Hydrophilicity: The presence of tetrahydropyran rings suggests a likely hydrophilic character, which can further increase solubility in aqueous environments.
  • Solvent Specificity: Solubility may vary considerably depending on the solvent utilized; for instance, dimethyl sulfoxide (DMSO) and ethanol could potentially dissolve the compound more effectively than non-polar solvents like hexane.

In summary, the solubility of this compound is expected to be significantly influenced by its complex structure and the inherent chemical properties of its functional groups. Testing in various solvents is essential to fully understand its solubility profile and suitability for specific applications.

Interesting facts

Interesting Facts About 12-Hydroxy-2-[(5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]-9-(3-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl)oxy-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione

This complex compound is a fascinating example of organic chemistry that showcases the intricate nature of molecular structures. Its unique configuration not only underscores the beauty of chemical synthesis but also points to its potential applications in various fields.

Key Features:

  • Structural Complexity: The compound contains multiple functional groups and a bicyclic structure, making it a subject of interest in stereochemistry.
  • Biological Relevance: Compounds like this are often studied for their pharmacological properties and potential use in medicines. The presence of multiple hydroxyl groups may suggest possible roles in biological systems.
  • Synthetic Pathways: The synthesis of such a compound typically involves several steps and can serve as an excellent case study in chemical education, illustrating concepts such as regioselectivity and stereoselectivity.
  • Natural Products: The detailed composition hints at a potential origin from natural products or as a synthetic analog, making it valuable for researchers investigating natural substance derivatives.

As scientists delve deeper into the study of this compound, they often reference it as a blend of art and science, demonstrating how creativity combines with rigorous methodology in the field of organic chemistry. Exploring compounds with such structural richness can inspire new discoveries and lead to breakthroughs in drug design and other applications.

In summary, 12-hydroxy-2-[(5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]-9-(3-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl)oxy-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione is not just a chemical entity, but a portal into understanding the vast complexity of molecular chemistry.

Synonyms
12-Hydroxy-2-[(5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl)oxymethyl]-9-(3-hydroxy-4-methoxy-6-methyloxan-2-yl)oxy-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione