Interesting facts
Interesting Facts about 12,19-Difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
This compound, though complex in its structure, represents a fascinating area of study within organic and medicinal chemistry. Here are several intriguing aspects of this compound:
- Unique Structural Features: The pentacyclic structure is a remarkable representation of nature's ability to form intricate molecular frameworks. Such structures are often found in various natural products with significant biological activities.
- Dual Functionality: The presence of both hydroxy and fluoro groups introduces an interesting layer of reactivity. These functional groups can significantly influence the compound's chemical behavior and its interaction with biological systems.
- Potential Biological Activity: Compounds that contain multiple functional groups, like this one, are often scrutinized for their pharmacological potential. The 'dioxapentacyclo' core suggests possible activity that might be explored in drug discovery.
- Cyclic Structures: The formation of large cyclic compounds often requires advanced synthetic techniques, making them valuable targets in synthetic chemistry. Understanding how to synthesize such compounds is crucial for developing new drugs.
- Applications in Research: This compound can serve as a model in studies related to drug development, particularly in understanding the effects of fluorination on biological activity and metabolic stability.
- Chemical Modifications: The various substituents attached to the core structure hint at opportunities for chemical modifications that could enhance desirable properties, such as increased potency or selectivity.
In conclusion, the exploration of such complex compounds not only expands our understanding of chemistry but also opens pathways to potentially groundbreaking discoveries in medicine and pharmacology. As Albert Einstein once said, "The whole of science is nothing more than a refinement of everyday thinking." This compound exemplifies that philosophy, bridging the gap between theoretical chemistry and real-world applications.
Synonyms
Flucort
Fluovitef
Fluvean
6.alpha.-Fluorotriamcinolone acetonide
N-Synalar (Salt/Mix)
Neo-Synalar (Salt/Mix)
MLS001196984
SCHEMBL1276243
CHEMBL1599911
DTXSID70859067
FEBLZLNTKCEFIT-UHFFFAOYSA-N
HMS2856O09
(6alpha,9alpha,11beta,16beta)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
1262192-25-5
STL481763
AKOS001650096
AS-11053
SMR000555611
SY057543
DB-055059
NS00077180
UNM000000588701
6.alpha.,9.alpha.-Difluoro-16.alpha.-hydroxyprednisolone 16,17-acetonide
(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^{2,9.0^{4,8.0^{13,18]icosa-14,17-dien-16-one
(6.alpha.,11.beta.,16.alpha.)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
(6.alpha.,11.beta.,16.alpha.)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidine)bis(oxy)]pregna-1,4-diene-3,20-dione
4b,12-Difluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H,8H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
4b,12-difluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
4b,12-Difluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one #
6.alpha.,9-Difluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone
Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,12-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6.alpha.,11.beta.,16.alpha.)-
Pregna-1,4-diene-3,20-dione, 6.alpha.,9-difluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
Solubility of 12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
The solubility of the compound C23H29F2O6 is influenced by several key factors related to its chemical structure. Here are some important aspects to consider:
In summary, understanding the solubility of this complex compound requires examining its polar and non-polar characteristics, as well as the interactions it may undergo in various solvents. While the potential for solubility exists due to functional groups, the overall hydrophobic nature introduced by the structure may pose limitations. Always consider experimental data for accurate assessments of solubility in practical scenarios.