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1,2,3-Tribenzylguanidine

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Identification
Molecular formula
C22H23N3
CAS number
1023-30-1
IUPAC name
1,2,3-tribenzylguanidine
State
State

At room temperature, 1,2,3-tribenzylguanidine is in the solid state. It is typically crystalline with a stable structure under normal conditions.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
486.00
Boiling point (Kelvin)
759.15
General information
Molecular weight
328.44g/mol
Molar mass
328.4360g/mol
Density
1.1840g/cm3
Appearence

1,2,3-Tribenzylguanidine appears as a solid, typically in the form of white to off-white crystals or powder. It is known for being relatively stable under standard temperature and pressure conditions.

Comment on solubility

Solubility of 1,2,3-Tribenzylguanidine

1,2,3-Tribenzylguanidine is a fascinating compound when it comes to its solubility characteristics. Several factors influence its behavior in various solvents:

  • Polarity: The presence of multiple benzyl groups within the molecule increases its hydrophobic character, which often leads to lower solubility in polar solvents like water.
  • Organic Solvents: This compound is generally more soluble in non-polar or moderately polar organic solvents such as ethanol, chloroform, or dimethyl sulfoxide (DMSO).
  • Temperature Dependence: Like many organic compounds, solubility can increase with temperature, which may enhance its dissolution in solvents by increasing molecular movement.

To summarize, 1,2,3-tribenzylguanidine tends to exhibit limited solubility in water due to its hydrophobic characteristics, while it is readily soluble in a range of organic solvents. Thus, its solubility profile is a reflection of the balance between its molecular structure and the nature of the solvent used.

Interesting facts

Interesting Facts about 1,2,3-Tribenzylguanidine

1,2,3-Tribenzylguanidine is a fascinating chemical compound that has garnered the attention of researchers due to its unique structure and potential applications. Here are some intriguing aspects of this compound:

  • Structure and Composition: This compound consists of a guanidine core, substituted with three benzyl groups. The placement of these groups on the guanidine molecule gives it interesting physicochemical properties that are crucial for its functionality.
  • Biological Activity: Studies suggest that 1,2,3-tribenzylguanidine exhibits significant biological activity, particularly as a potential agent for treating a variety of conditions. This includes its use in neural and cardiovascular pharmacology, making it a compound of interest in medicinal chemistry.
  • Applications in Research: The compound is often utilized in research to probe ion channels and receptors, showcasing its vital role in understanding cellular signaling pathways. This highlights its importance in areas such as neurobiology and drug development.
  • Synthetic Versatility: The synthesis of 1,2,3-tribenzylguanidine involves accessible organic reactions, which makes it a favored target for chemistry students and professionals seeking to experiment with aromatic substitution reactions.
  • Pharmacophore Identification: Researchers are continuously exploring the pharmacophoric features of 1,2,3-tribenzylguanidine, aiming to identify and optimize its biological activity, which can lead to the development of novel therapeutic agents.

In conclusion, 1,2,3-tribenzylguanidine is more than just a chemical entity; it embodies the interplay between chemistry and biology, making it a pivotal subject in both fields. As more studies are conducted, we may uncover even more potential applications and insights related to this intriguing compound.

Synonyms
1,2,3-tribenzylguanidine
MLS002638736
5440-98-2
NSC20644
SCHEMBL1792490
CHEMBL1702199
SCHEMBL16443508
DTXSID30275022
HMS3078C17
NSC-20644
SMR001548203
DS-008175