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1,2,3-Triphenylguanidine

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Identification
Molecular formula
C19H17N3
CAS number
102-06-7
IUPAC name
1,2,3-triphenylguanidine
State
State

At room temperature, 1,2,3-Triphenylguanidine is typically found in solid form. It is usually stable under normal conditions, although it requires proper handling to maintain its structural integrity and prevent decomposition.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
352.00
Boiling point (Kelvin)
625.15
General information
Molecular weight
305.40g/mol
Molar mass
305.3960g/mol
Density
1.2090g/cm3
Appearence

1,2,3-Triphenylguanidine typically presents as a white to off-white crystalline powder. It may have a faint odor due to its organic nature, and the crystal size can vary based on the manufacturing process.

Comment on solubility

Solubility of 1,2,3-Triphenylguanidine

1,2,3-Triphenylguanidine, with the chemical formula C20H22N4, exhibits intriguing solubility characteristics that are essential for its application in various chemical processes. Its solubility can be summarized as follows:

  • Solvent Interaction: This compound is generally soluble in organic solvents such as ethanol, acetone, and chloroform, largely due to its non-polar characteristics.
  • Water Solubility: However, 1,2,3-triphenylguanidine tends to show limited solubility in water, which poses a challenge in certain applications requiring aqueous environments.
  • Influence of Temperature: The solubility may increase with temperature, indicating that heating the solvent can enhance dissolution.
  • pH Sensitivity: The solubility might also fluctuate with changes in pH, making careful monitoring a necessity in experiments.

As a general rule, "like dissolves like," which is crucial to understanding why 1,2,3-triphenylguanidine favors organic solvents over polar solvents like water. That said, the unique structure of this compound contributes to its relatively low solubility in polar media, yet its ability to interact effectively with non-polar environments opens up a myriad of potential applications.

Interesting facts

Interesting Facts about 1,2,3-Triphenylguanidine

1,2,3-Triphenylguanidine is an intriguing organic compound that has garnered significant interest in both academic and industrial fields due to its versatile functionalities and applications. Here are some fascinating insights about this compound:

  • Background: 1,2,3-Triphenylguanidine is classified as a guanidine derivative, which typically features notable biological activity, including potential medicinal properties.
  • Applications: One of the prominent uses of this compound is as an accelerator in the synthesis of rubber, particularly for the vulcanization process. This helps improve the durability and elasticity of rubber products, making them more viable for various applications.
  • Biological Activity: Research has suggested that guanidine derivatives, including 1,2,3-triphenylguanidine, may exhibit antifungal and antimicrobial properties, enhancing their significance in pharmaceutical chemistry.
  • Synthesis: The synthesis of 1,2,3-triphenylguanidine typically involves a reaction between phenyl isocyanate and an appropriate amine source, showcasing the compound's accessibility in a laboratory setting.
  • Educational Relevance: This compound serves as an excellent teaching tool in organic chemistry curricula to demonstrate the concepts of substitution reactions and aromaticity, which are foundational topics for students.
  • Environmental Impact: While 1,2,3-triphenylguanidine is primarily used in industrial applications, there is an ongoing effort to evaluate its environmental impact, especially regarding its lifetime and degradation in natural environments.

As we delve deeper into the realm of organic chemistry, compounds like 1,2,3-triphenylguanidine remind us of the incredible intricacies and functionalities that can arise from relatively simple structures.


Synonyms
1,2,3-Triphenylguanidine
101-01-9
N,N',N''-Triphenylguanidine
Guanidine, N,N',N''-triphenyl-
sym-Triphenylguanidine
Triphenylguanidine
Guanidine, triphenyl-
1,2,3-Trifenylguanidin
GUANIDINE, 1,2,3-TRIPHENYL-
1,2,3-Trifenylguanidin [Czech]
NSC 4051
EINECS 202-907-9
BRN 2217588
I64B170QFG
AI3-00102
NSC-4051
DTXSID2059223
4-12-00-00866 (Beilstein Handbook Reference)
MFCD00020648
UNII-I64B170QFG
triphenylguanidin
NSC4051
N,N<<,N<<<<-Triphenylguanidine
1,3-Triphenylguanidine
Maybridge4_003421
N,N''-Triphenylguanidine
1,2,3-Triphenylquanidine
Guanidine,2,3-triphenyl-
WLN: RNUYMR & MR
N,N'N''-Triphenylguanidine
SCHEMBL78799
CBDivE_001970
Guanidine,N',N''-triphenyl-
DTXCID0032572
HMS1530L11
AKOS000508148
CCG-244481
NCGC00175862-01
AS-60183
NS00021438
T1316
D95230
AE-641/02487035
BRD-K50821896-001-01-8
Q27280495
202-907-9
InChI=1/C19H17N3/c1-4-10-16(11-5-1)20-19(21-17-12-6-2-7-13-17)22-18-14-8-3-9-15-18/h1-15H,(H2,20,21,22