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Podophyllotoxin

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Identification
Molecular formula
C22H22O8
CAS number
518-28-5
IUPAC name
1,2,3,10-tetramethoxy-7H-benzo[a]heptalen-9-one
State
State
Podophyllotoxin is typically in a solid state at room temperature.
Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.15
General information
Molecular weight
414.41g/mol
Molar mass
414.4130g/mol
Density
1.3600g/cm3
Appearence
Podophyllotoxin is typically a white to off-white crystalline solid.
Comment on solubility

Solubility of 1,2,3,10-tetramethoxy-7H-benzo[a]heptalen-9-one

The solubility of 1,2,3,10-tetramethoxy-7H-benzo[a]heptalen-9-one can significantly influence its application in various chemical and pharmaceutical processes. Understanding the solubility of this organic compound is critical for its utilization in formulations and reactions.

Key Points About Solubility

  • Solvent Polarity: The solubility of this compound may vary depending on the polarity of the solvent used. Polar solvents, such as water and methanol, may show limited solubility due to the hydrophobic nature of the compound.
  • Temperature Effect: Higher temperatures generally increase solubility. Investigating how temperature affects solubility can be crucial for dissolving the compound to the desired concentration.
  • Crystallization Behavior: The compound’s crystalline structure may also play a role in how easily it can dissolve. If it forms strong intermolecular interactions, solubility will be further hindered.
  • pH Dependence: The solubility might exhibit variability based on the pH of the solution, which can alter the compound's ionization state and, ultimately, its solubility profile.

In summary, while 1,2,3,10-tetramethoxy-7H-benzo[a]heptalen-9-one does not have extensive solubility in all solvents, understanding its solubility properties can guide scientists in selecting suitable conditions for its effective use. As the saying goes, “The right solvent is key to unlocking the potential of a compound.”

Interesting facts

Interesting Facts about 1,2,3,10-tetramethoxy-7H-benzo[a]heptalen-9-one

1,2,3,10-tetramethoxy-7H-benzo[a]heptalen-9-one is a fascinating chemical compound with a notable structure that captures the interest of chemists and organic researchers alike. Here are some intriguing aspects of this compound:

  • Unique Structure: The compound features a complex arrangement of fused aromatic rings, characteristic of polycyclic aromatic compounds. Its tetracyclic structure contributes to its chemical behavior and reactivity.
  • Functional Groups: With four methoxy groups in its structure, this compound showcases interesting electronic effects that can influence its reactivity and interaction with other molecules.
  • Biological Activity: Compounds like 1,2,3,10-tetramethoxy-7H-benzo[a]heptalen-9-one have been investigated for their potential biological activities, including antioxidant and antimicrobial properties. Studies suggest that the methoxy groups may enhance these activities, making them a point of interest in medicinal chemistry.
  • Applications in Research: Due to its unique properties, this compound is often used in various research domains, including material science and organic synthesis. Its derivatives may pave the way for new materials with specialized functions.
  • Historical Context: Polycyclic aromatic compounds have been studied for decades, contributing to our understanding of organic chemistry and the development of synthetic organic methodologies.

In summary, 1,2,3,10-tetramethoxy-7H-benzo[a]heptalen-9-one not only holds aesthetic appeal due to its intricate structure but also presents numerous opportunities for further research and application in various fields. As noted by chemists, "the uniqueness of a compound often lies in its ability to bridge various disciplines," and this compound exemplifies that connection.

Synonyms
Deacetamido-6-dehydrocolchicine
Deacetamido-5,6-didehydrocolchicine
5,6-Dehydro-7-deacetamidocolchicine
BRN 2482144
COLCHICINE, 5,6-DIDEHYDRODEACETAMIDO-
DTXSID70162881
Colchicine, deacetamido-6-dehydro-
Benzo(alpha)heptalen-9(5H)-one, 1,2,3,10-tetramethoxy-
DTXCID5085372
Benzo(a)heptalen-9(5H)-one, 1,2,3,10-tetramethoxy-
Colchicine, deacetamido-5,6-didehydro-
NSC317028
CHEMBL89900
NSC-317028
76265-61-7