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6-Hydroxy-1,2,3,4-tetrahydroisoquinoline

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Identification
Molecular formula
C9H11NO
CAS number
24544-06-7
IUPAC name
1,2,3,4-tetrahydroisoquinolin-6-ol
State
State
The compound is typically in a solid state at room temperature, often presented as a crystalline or powdery substance.
Melting point (Celsius)
-10.00
Melting point (Kelvin)
263.15
Boiling point (Celsius)
285.20
Boiling point (Kelvin)
558.35
General information
Molecular weight
147.19g/mol
Molar mass
147.1890g/mol
Density
1.1760g/cm3
Appearence

6-Hydroxy-1,2,3,4-tetrahydroisoquinoline typically appears as an off-white to pale yellow solid. It features a crystalline structure and can be visually characterized by its powdery or granular form.

Comment on solubility

Solubility of 1,2,3,4-Tetrahydroisoquinolin-6-ol

1,2,3,4-tetrahydroisoquinolin-6-ol, a compound structurally related to isoquinoline, showcases intriguing solubility characteristics that are noteworthy in various contexts:

  • Polar Solvents: This compound tends to be soluble in polar solvents such as water, owing to the presence of hydroxyl groups (−OH) that can form hydrogen bonds.
  • Non-Polar Solvents: In contrast, the solubility in non-polar solvents (like hexane) is limited, observing the common trend of polar compounds!
  • Effect of pH: The solubility can vary significantly with pH; under acidic conditions, the presence of additional protons may enhance solubility due to increased ionization.
  • Temperature Influence: Increasing temperature often leads to improved solubility, making solubilization easier in preparation for various applications.

To summarize, the solubility of 1,2,3,4-tetrahydroisoquinolin-6-ol is influenced by its chemical structure and environmental conditions. Its soluble nature in polar solvents enhances its potential use in pharmaceuticals and organic synthesis. Understanding these properties is crucial for maximizing the effectiveness of this compound in practical applications.

Interesting facts

Interesting Facts About 1,2,3,4-Tetrahydroisoquinolin-6-ol

1,2,3,4-Tetrahydroisoquinolin-6-ol is a fascinating compound belonging to the class of isoquinolines. Its unique structure and functional groups contribute to a variety of intriguing properties and potential applications. Here are some key points of interest:

  • Medicinal Potential: This compound has garnered attention in the field of pharmacology. Studies suggest that isoquinoline derivatives possess a range of biological activities, including antioxidant, anti-inflammatory, and even antidepressant properties.
  • Chemical Versatility: The presence of multiple functional groups enables this compound to engage in various chemical reactions. It's particularly interesting for those studying organic synthesis, as it can serve as a building block for creating more complex molecules.
  • Research Studies: Numerous research studies have focused on derivatives of tetrahydroisoquinolines, exploring their potential in developing treatments for neurological disorders. For instance, there are implications in treating conditions like Parkinson's disease due to the neuroprotective effects observed in some studies.
  • Natural Occurrence: Isoquinolines are often found in a variety of natural products. This raises questions about the ecological roles these compounds may play, as well as their relevance to traditional medicine.
  • Interdisciplinary Appeal: The study of 1,2,3,4-tetrahydroisoquinolin-6-ol transcends disciplines. Chemists, pharmacologists, and biologists all find significance in the compound, enhancing collaboration across fields.

In summary, 1,2,3,4-tetrahydroisoquinolin-6-ol stands out due to its multifunctional potential and the variety of applications in research. Scientists are continually exploring its characteristics and functionalities, making it a promising compound in medicinal chemistry and organic synthesis.

Synonyms
1,2,3,4-tetrahydroisoquinolin-6-ol
6-Hydroxy-1,2,3,4-tetrahydroisoquinoline
814-570-0
14446-24-3
1,2,3,4-Tetrahydro-isoquinolin-6-ol
1,2,3,4-Tetrahydro-6-isoquinolinol
6-ISOQUINOLINOL, 1,2,3,4-TETRAHYDRO-
MFCD01717047
CHEMBL310736
6-Hydroxy-1,2,3,4-tetrahydro-isoquinoline
BRN 0127578
6-Hydroxytetrahydroisochinolin
6WR7DU65P7
SCHEMBL1017452
SCHEMBL3245289
SCHEMBL5844893
SCHEMBL5844898
SCHEMBL7646302
SCHEMBL29514775
DTXSID80162711
SCMZIFSYPJICCV-UHFFFAOYSA-N
CS-M3291
BDBM50024822
AKOS006333936
AB09835
AC-28820
SY003117
DB-012697
H1572
EN300-96853
Z3018438111