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1,2,3,4,5-Pentachloro-6-methoxybenzene

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Identification
Molecular formula
C7H3Cl5O
CAS number
84852-53-9
IUPAC name
1,2,3,4,5-pentachloro-6-methoxy-benzene
State
State

At room temperature, 1,2,3,4,5-Pentachloro-6-methoxybenzene is in a solid state.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
328.00
Boiling point (Kelvin)
601.15
General information
Molecular weight
280.39g/mol
Molar mass
280.3890g/mol
Density
1.8600g/cm3
Appearence

1,2,3,4,5-Pentachloro-6-methoxybenzene appears as a white to off-white crystalline solid. It is not soluble in water but can dissolve in organic solvents.

Comment on solubility

Solubility of 1,2,3,4,5-Pentachloro-6-methoxy-benzene

1,2,3,4,5-Pentachloro-6-methoxy-benzene is an intriguing compound in terms of solubility, primarily due to the presence of multiple chlorinated groups which significantly influence its interactions with solvents. Here are some key points regarding its solubility:

  • Chlorinated Nature: The presence of five chlorine atoms in the structure tends to increase the hydrophobic character of the compound. As a result, water solubility is expected to be low.
  • Organic Solvents: It may exhibit better solubility in organic solvents such as:
    • Hexane
    • Toluene
    • Chloroform
  • Reactivity with Water: Given its structure, 1,2,3,4,5-pentachloro-6-methoxy-benzene does not readily form hydrogen bonds with water, which limits its solubility.
  • Temperature Effects: Like many organochlorines, its solubility may increase with temperature, making it more soluble at higher temperatures in suitable organic solvents.

In summary, while 1,2,3,4,5-pentachloro-6-methoxy-benzene shows low solubility in water, it is more compatible with non-polar organic solvents, making it useful in various applications where organic phases are utilized. Understanding these solubility characteristics is essential for effective handling and application in chemical processes.

Interesting facts

Interesting Facts about 1,2,3,4,5-Pentachloro-6-methoxy-benzene

1,2,3,4,5-Pentachloro-6-methoxy-benzene, also known as a halogenated aromatic compound, is noteworthy for several reasons:

  • Halogenation: This compound features five chlorine atoms, making it one of the highly chlorinated derivatives of benzene. The presence of multiple chlorine atoms significantly alters its chemical properties, enhancing its reactivity and stability.
  • Environmental Impact: Halogenated compounds like this one are of great interest to environmental chemists. Their chlorinated structure can lead to persistent environmental contaminants, raising questions about their degradation pathways and potential bioaccumulation in ecosystems.
  • Applications: Compounds with a similar structure are often explored for various applications, including use in agrochemicals, pharmaceuticals, and as intermediates in organic synthesis. The methoxy group also introduces interesting electron-donating properties, which can influence the compound's chemical behavior.
  • Toxicology: With the increasing focus on sustainability and safety, the toxicity of such compounds is a major area of research. Understanding the health effects of exposure to chlorinated compounds is crucial, as some can have deleterious effects on human health and the environment.
  • Research Potential: The unique structure of 1,2,3,4,5-pentachloro-6-methoxy-benzene makes it a valuable subject for research. Scientists can study its reactivity, interaction with biological systems, and mechanisms of action in the environment.

As a chemistry student or researcher, one should appreciate the complexity and implications of working with such chlorinated compounds. The balance between their utility and potential risks makes them a critical topic in both organic chemistry and environmental science.

Synonyms
PENTACHLOROANISOLE
Pentachlorophenyl methyl ether
Pentachloranisole
Benzene, pentachloromethoxy-
Pentachloromethoxybenzene
Methyl pentachlorophenate
Methyl pentachlorophenyl ester
Benzene, 1,2,3,4,5-pentachloro-6-methoxy-
2,3,4,5,6-Pentachloroanisole
Methyl pentachlorophenyl ether
Anisole, 2,3,4,5,6-pentachloro-
Ether, methyl pentachlorophenyl
NCI-C56520
CCRIS 2119
HSDB 4218
PCP, Methyl ether
UNII-14D125MH3W
BRN 2052667
DTXSID2021103
AI3-15752
14D125MH3W
NSC-141502
DTXCID501103
PENTACHLOROANISOLE [HSDB]
4-06-00-01027 (Beilstein Handbook Reference)
NSC 141502
PCP methyl ether
Benzene, pentachloromethoxy
2,3,4,5,6Pentachloroanisole
Anisole, 2,3,4,5,6pentachloro
Benzene, pentachloromethoxy-(9CI)
PENTACHLOROPHENOL METHYL ETHER
625-770-0
bbabscytnhokog-uhfffaoysa-n
1825-21-4
1,2,3,4,5-Pentachloro-6-methoxybenzene
CAS-1825-21-4
2,4,5,6-Pentachloroanisole
SCHEMBL301807
CHEMBL3182755
Anisole,3,4,5,6-pentachloro-
CHEBI:232435
WLN: GR BG CG DG EG FO1
Tox21_201560
Tox21_302835
NSC141502
AKOS015888397
NCGC00249070-01
NCGC00256549-01
NCGC00259109-01
AS-64836
1,2,3,4,5-Pentachloro-6-methoxy-benzene
1,2,3,4,5-Pentachloro-6-methoxybenzene #
CS-0333795
NS00004402
Pentachloroanisole 10 microg/mL in Cyclohexane
Pentachloroanisole 1000 microg/mL in Methanol
Q27251610