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Hexafluorobenzene

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Identification
Molecular formula
C6F6
CAS number
392-56-3
IUPAC name
1,2,3,4,5,6-hexafluorobenzene
State
State

At room temperature, hexafluorobenzene is in a liquid state. It remains stable across a range of temperatures, making it useful as a solvent in various chemical reactions.

Melting point (Celsius)
5.20
Melting point (Kelvin)
278.40
Boiling point (Celsius)
80.10
Boiling point (Kelvin)
353.20
General information
Molecular weight
186.05g/mol
Molar mass
186.0540g/mol
Density
1.6130g/cm3
Appearence

Hexafluorobenzene is a colorless liquid with a distinct aromatic odor. It is clear and transparent, resembling benzene in structure but with all hydrogen atoms replaced by fluorine. Due to the presence of multiple fluorine atoms, the compound exhibits significant chemical stability and low reactivity compared to benzene.

Comment on solubility

Solubility of 1,2,3,4,5,6-hexafluorobenzene

1,2,3,4,5,6-hexafluorobenzene (C6F6) exhibits interesting solubility properties. Due to its unique structure, this compound is characterized by the following solubility behavior:

  • Polarity: The presence of six fluorine atoms contributes to a high degree of electronegativity, resulting in a polar nature.
  • Solvent Compatibility: It is primarily soluble in non-polar organic solvents, such as:
    • Hexane
    • Chloroform
    • Carbon tetrachloride
  • Water Solubility: The overall solubility in water is very low due to the hydrophobic nature of the benzene ring.
  • Temperature Influence: Like many organic compounds, its solubility can increase with temperature, enhancing interactions with non-polar solvents.

Overall, the solubility of 1,2,3,4,5,6-hexafluorobenzene is a fascinating topic, reflecting the balance between its polarity and the characteristics of the solvents used.

Interesting facts

Interesting Facts about 1,2,3,4,5,6-Hexafluorobenzene

1,2,3,4,5,6-Hexafluorobenzene is a fascinating compound that finds significance in various fields of chemistry. As a derivative of benzene, this compound has undergone substantial transformation by substituting each of its hydrogen atoms with fluorine, resulting in a highly fluorinated aromatic compound.

Unique Properties:

  • Fluorination: The presence of six fluorine atoms dramatically influences the chemical behavior of the compound. Fluorine is highly electronegative, which leads to unique electron density distribution.
  • Inertness: Due to the strong C-F bonds, 1,2,3,4,5,6-hexafluorobenzene exhibits a level of chemical inertness, making it useful in applications where reactivity needs to be minimized.
  • Solvent Potential: This compound is often used as a solvent in fluorous phase organic reactions, providing a distinctive environment for reaction conditions.

Applications:

  • Material Science: Utilized in the development of advanced materials, particularly those requiring high thermal and chemical stability.
  • Pharmaceuticals: It serves as an intermediary in the synthesis of various pharmaceutical compounds, where the incorporation of fluorine enhances bioactivity or pharmacokinetics.
  • Analytical Chemistry: Its unique properties lend themselves to applications in analytical chemistry, especially in magnetic resonance spectroscopy.

Embracing **1,2,3,4,5,6-hexafluorobenzene** in your studies provides insights into the broader implications of fluorinated compounds in modern chemistry. As quoted by a prominent chemist, “Understanding the intricacies of fluorinated compounds opens doors to innovative chemistry solutions.”
Exploring its diverse applications brings to light the exciting potential of these versatile molecules!

Synonyms
HEXAFLUOROBENZENE
392-56-3
Perfluorobenzene
1,2,3,4,5,6-Hexafluorobenzene
Benzene, hexafluoro-
CP 28
Hexafluorbenzol
EINECS 206-876-2
MFCD00000288
NSC 21628
CMC18T611K
NSC-21628
HEXAFLUOROBENZENE [MI]
DTXSID5043924
CHEBI:38589
Benzene, 1,2,3,4,5,6-hexafluoro-
hexa fluorobenzene
C6F6
UNII-CMC18T611K
hexafluoro benzene
Benzene, hexafluoro
Hexafluorobenzene, 99%
DTXCID3023924
ZQBFAOFFOQMSGJ-UHFFFAOYSA-
WLN: FR BF CF DF EF FF
NSC21628
Benzene, 1,2,3,4,5,6hexafluoro
STL453689
AKOS000120141
FS-5085
s10932
Hexafluorobenzene,= 99.5%, NMR grade
Hexafluorobenzene, >=99.5%, NMR grade
DB-001383
CS-0121350
H0085
NS00043152
EN300-19365
Q412413
F8881-4208
InChI=1/C6F6/c7-1-2(8)4(10)6(12)5(11)3(1)9
206-876-2
HFB