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Triclosan

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Identification
Molecular formula
C12H7Cl3O2
CAS number
3380-34-5
IUPAC name
1,2,4-trichloro-5-(4-chlorophenyl)sulfanyl-benzene
State
State

Triclosan is typically found in a solid state at room temperature. It is often used in a powdered form in various formulations.

Melting point (Celsius)
55.00
Melting point (Kelvin)
328.15
Boiling point (Celsius)
120.00
Boiling point (Kelvin)
393.15
General information
Molecular weight
289.55g/mol
Molar mass
289.5450g/mol
Density
1.5524g/cm3
Appearence

Triclosan is a white to off-white crystalline solid that may appear as a powder. It is commonly used in personal care products and may have a faint aromatic odor.

Comment on solubility

Solubility of 1,2,4-trichloro-5-(4-chlorophenyl)sulfanyl-benzene

The solubility of 1,2,4-trichloro-5-(4-chlorophenyl)sulfanyl-benzene can be described as follows:

  • Polarity: This compound contains multiple chlorinated groups and a sulfanyl functional group, contributing to its overall polarity. However, the presence of bulky aromatic rings may hinder full solvation.
  • Insolubility in Water: Due to its significant hydrophobic character stemming from chlorinated aromatic structures, 1,2,4-trichloro-5-(4-chlorophenyl)sulfanyl-benzene is likely to be insoluble in water.
  • Solubility in Organic Solvents: The compound may exhibit appreciable solubility in organic solvents such as:
    • Chloroform
    • Benzene
    • Dimethyl sulfoxide (DMSO)

In practical terms, the solubility of this compound will largely depend on the nature of the solvent used. For applications requiring dissolution, selecting a non-polar or slightly polar organic solvent would be ideal.

In summary, understanding the solubility of 1,2,4-trichloro-5-(4-chlorophenyl)sulfanyl-benzene involves considering its molecular structure, polar functional groups, and the solvent characteristics, leading to the conclusion that it is primarily soluble in organic media and insoluble in aqueous environments.

Interesting facts

Interesting Facts about 1,2,4-trichloro-5-(4-chlorophenyl)sulfanyl-benzene

1,2,4-trichloro-5-(4-chlorophenyl)sulfanyl-benzene is an intriguing organic compound demonstrating the fascinating interplay between chlorine atoms and sulfur functionalities. Here are some key points that amplify its significance in the field of chemistry:

  • Chlorinated Aromatics: This compound belongs to the class of chlorinated aromatic compounds, which are known for their stability and potential applications in various industries.
  • Environmental Considerations: Due to the presence of multiple chlorine atoms, this compound may have environmental implications, as chlorinated compounds can persist in the environment and bioaccumulate.
  • Biological Activity: Compounds similar to this one have been studied for their biological activities, which could include antimicrobial or antifungal properties. The presence of chloro groups can influence the compound's interaction with biological systems.
  • Synthesis Challenges: The synthesis of such halogenated compounds can be complex, often requiring specific reaction conditions to achieve desired substitutions without over-reactions or degradation.
  • Pharmaceutical Potential: The structural features of this compound can inspire novel drug development approaches in medicinal chemistry, particularly in targeting diseases related to oxidative stress or microbial infections.

This compound exemplifies the intricate structures that can arise from a combination of functional groups and halogens, providing valuable insights into both synthetic strategies and potential applications in various fields. In the words of a famous chemist, "Chemistry is the art of composition; the more elements you can use, the more you can create."

Synonyms
TETRASUL
Animert
Tetradisul
Animert V-10
Animert V-10K
Animert V-101
Philips-duphar V-101
2,4,4',5-Tetrachlorodiphenyl sulfide
Caswell No. 213
Tetrasul [BSI:ISO]
V-101
p-Chlorophenyl 2,4,5-trichlorophenyl sulfide
4-Chlorophenyl 2,4,5-trichlorophenyl sulfide
2,4,5,4'-Tetrachlorodiphenyl sulfide
Benzene, 1,2,4-trichloro-5-((4-chlorophenyl)thio)-
ENT 27,115
Sulfide, p-chlorophenyl 2,4,5-trichlorophenyl
2,4,4',5-Tetrachlorodiphenyl sulphide
UNII-BEO7JP5U0R
BEO7JP5U0R
V 101
EINECS 218-761-4
3,4,6,4'-Tetrachlor-diphenylsulfid
EPA Pesticide Chemical Code 079201
BRN 1884271
DTXSID5020314
AI3-27115
2-Chlorophenyl 2,4,5-trichlorophenyl sulfide
TETRASUL [ISO]
3,4,6,4'-Tetrachlor-diphenylsulfid [German]
4-Chlorophenyl 2,4,5-trichlorophenyl sulphide
1,2,4-Trichloro-5-(4-(chlorophenyl)thio)benzene
DTXCID70314
Benzene, 1,2,4-trichloro-5-[(4-chlorophenyl)thio]-
1,2,4-trichloro-5-[(4-chlorophenyl)thio]benzene
1,2,4-Trichloro-5-[(4-chlorophenyl)sulfanyl]benzene
1,2,4-TRICHLORO-5-((4-CHLOROPHENYL)THIO)BENZENE
1,2,4-trichloro-5-((4-chlorophenyl)sulfanyl)benzene
1,2,4-Trichloro-5-(4-(chlorophenyl)thio)benzene (9CI)
4-chlorophenyl-2,4,5-trichlorophenylsulfide
218-761-4
4-06-00-01635 (beilstein handbook reference)
quwsdlybovgocw-uhfffaoysa-n
2227-13-6
1,2,4-trichloro-5-(4-chlorophenyl)sulfanylbenzene
CHEBI:82162
p-Chlorophenyl-2,4,5-trichlorophenyl sulfide
CAS-2227-13-6
Tetrasul 1000 microg/mL in Acetone
BENZENE,1,2,4-TRICHLORO-5-[(4-CHLOROPHENYL)THIO]-
SCHEMBL26508
CHEMBL1365576
Tox21_202392
Tox21_302984
AKOS024319292
DB12838
NCGC00166163-01
NCGC00166163-02
NCGC00256524-01
NCGC00259941-01
DB-045861
HY-124901
CS-0088830
NS00004438
C19032
Q15632887
1,2,4-Trichloro-5-[(4-chlorophenyl)sulfanyl]benzene #