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1,2,5-trimethyl-5-(1-piperidyl)piperidin-4-one

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Identification
Molecular formula
C13H24N2O
CAS number
123-39-7
IUPAC name
1,2,5-trimethyl-5-(1-piperidyl)piperidin-4-one
State
State

At room temperature, it is typically in a liquid state.

Melting point (Celsius)
28.70
Melting point (Kelvin)
301.90
Boiling point (Celsius)
354.50
Boiling point (Kelvin)
627.70
General information
Molecular weight
225.36g/mol
Molar mass
225.3610g/mol
Density
1.0298g/cm3
Appearence

It appears as a pale yellow liquid.

Comment on solubility

Solubility of 1,2,5-trimethyl-5-(1-piperidyl)piperidin-4-one

The solubility of 1,2,5-trimethyl-5-(1-piperidyl)piperidin-4-one in various solvents is an intriguing aspect that is influenced by its chemical structure. Here are some key points regarding its solubility:

  • Solvent Polarity: This compound is more likely to be soluble in polar solvents, such as water and alcohols, due to the presence of piperidyl groups that can engage in hydrogen bonding.
  • Hydrophobic Interactions: Its hydrophobic alkyl groups can reduce solubility in non-polar solvents, thus making it less soluble in hydrocarbons or non-polar organic solvents.
  • Temperature Effects: Like many organic compounds, its solubility can vary with temperature; typically, increased temperature leads to higher solubility.
  • Complexation: In some cases, formation of complexes with other molecules or ions can enhance solubility, particularly in a medicinal context.

Overall, understanding the solubility characteristics of this compound is critical for its applications in both laboratory and industrial settings. As with many compounds, pay attention to specific conditions under which its solubility may change.

Interesting facts

Interesting Facts about 1,2,5-Trimethyl-5-(1-piperidyl)piperidin-4-one

1,2,5-Trimethyl-5-(1-piperidyl)piperidin-4-one is a unique compound that showcases the fascinating interplay between various functional groups in organic chemistry. Here are some interesting aspects of this compound:

  • Synthetic Versatility: This compound can serve as a precursor in the synthesis of diverse chemical entities. Its structurally rich framework allows for various modifications, making it a versatile building block in drug discovery.
  • Role in Pharmacology: Compounds containing piperidine rings, like 1,2,5-trimethyl-5-(1-piperidyl)piperidin-4-one, can exhibit a range of biological activities. Researchers are particularly interested in their potential applications in developing medications for neurological disorders.
  • Structural Features: The presence of multiple methyl groups in the piperidine structure enhances its lipophilicity, which may influence the compound’s ability to penetrate biological membranes, thus impacting its biological effectiveness.
  • Analytical Chemistry: This compound can be analyzed through techniques such as NMR (Nuclear Magnetic Resonance) and Mass Spectrometry. These analyses help in understanding its conformational behavior and stability under various conditions.
  • Educational Importance: For chemistry students, studying this compound is an excellent way to understand concepts like steric hindrance, molecular geometry, and reactivity patterns in nitrogen-containing heterocycles.

In summary, 1,2,5-trimethyl-5-(1-piperidyl)piperidin-4-one represents an exciting intersection of organic synthesis, pharmacology, and structural chemistry. Its unique characteristics prompt ongoing exploration and discussion within the scientific community.