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1,2,5,6-tetrahydropyrimidine-4-thiol

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Identification
Molecular formula
C4H9N2S
CAS number
19925-50-3
IUPAC name
1,2,5,6-tetrahydropyrimidine-4-thiol
State
State

At room temperature, 1,2,5,6-Tetrahydropyrimidine-4-thiol is in a liquid state. It is not crystalline and is usually used in liquid form in various chemical applications and studies.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.15
Boiling point (Celsius)
227.00
Boiling point (Kelvin)
500.15
General information
Molecular weight
116.18g/mol
Molar mass
116.1760g/mol
Density
1.1910g/cm3
Appearence

1,2,5,6-Tetrahydropyrimidine-4-thiol is typically a colorless to slightly yellowish liquid. It is characterized by its sulfurous odor, which is typical for mercaptan compounds.

Comment on solubility

Solubility of 1,2,5,6-tetrahydropyrimidine-4-thiol

1,2,5,6-tetrahydropyrimidine-4-thiol, often abbreviated as THPT, is a unique compound known for its intriguing solubility properties. When evaluating the solubility of this thiol-containing pyrimidine, several important points emerge:

  • Water solubility: This compound is generally sparingly soluble in water, primarily due to its hydrophobic carbon backbone which limits interaction with water molecules.
  • Solvent compatibility: THPT demonstrates a greater solubility in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), making it suitable for applications in organic synthesis.
  • Temperature effects: Like many other organic compounds, the solubility of THPT can increase with temperature, as higher temperatures tend to disrupt intermolecular forces.

To summarize, while 1,2,5,6-tetrahydropyrimidine-4-thiol shows limited solubility in water, it readily dissolves in various organic solvents, increasing its utility in synthetic chemistry and biochemical applications. Understanding these solubility characteristics is critical for optimizing its use in different conditions.

Interesting facts

Interesting Facts about 1,2,5,6-Tetrahydropyrimidine-4-thiol

1,2,5,6-Tetrahydropyrimidine-4-thiol is a fascinating compound that captivates the interest of chemists and researchers alike. Here are some key points that make this compound noteworthy:

  • Diverse Applications: This compound is involved in a variety of applications, particularly in the field of medicinal chemistry. Its unique structure allows it to function as a precursor for the development of pharmaceutical agents, demonstrating potential in treating different diseases.
  • Structural Features: The tetrahydropyrimidine ring offers a special blend of rigidity and flexibility, which is crucial for its biological activity. The presence of the thiol group enhances its reactivity, making it valuable in various synthetic pathways.
  • Research Potential: Ongoing research aims to explore this compound's potential as an antioxidant and its role in biological processes. Its unique properties make it a candidate for further studies in organic synthesis and drug discovery.
  • Importance in Heterocyclic Chemistry: The study of heterocyclic compounds, which includes 1,2,5,6-tetrahydropyrimidine-4-thiol, is fundamental in creating new materials with specific properties. This compound exemplifies how modifications in the heterocyclic framework can lead to diverse functionalities.

In summary, 1,2,5,6-tetrahydropyrimidine-4-thiol is not just an ordinary compound; it embodies the intricate relationship between structure and function in the world of chemistry. Its ongoing exploration continues to reveal exciting possibilities in various scientific domains.