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Forskolin

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Identification
Molecular formula
C22H34O7
CAS number
66575-29-9
IUPAC name
13-acetoxy-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-14-tridecanoyloxy-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-diene-8-carboxylic acid
State
State

Forskolin is typically found as a solid at room temperature. This compound is often handled in powder form, making it convenient for use in research and formulation in supplement products.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
410.50g/mol
Molar mass
410.4890g/mol
Density
1.3405g/cm3
Appearence

Forskolin appears as a white to off-white crystalline powder. It is typically odorless and used commonly in its powder form for various applications. The purity of forskolin can affect its appearance, with higher purity samples being more consistently white.

Comment on solubility

Solubility of 13-acetoxy-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-14-tridecanoyloxy-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-diene-8-carboxylic acid

The solubility of the compound with the formula C22H34O7 can be extensively analyzed due to its unique structural characteristics. Solubility largely depends on a few key factors, and here are some considerations:

  • Hydrophilicity vs. Hydrophobicity: The presence of multiple hydroxyl (-OH) groups tends to enhance hydrophilic properties, potentially increasing solubility in polar solvents like water.
  • Hydrocarbon Chains: The long hydrocarbon components may introduce substantial hydrophobic characteristics, which could reduce water solubility but enhance solubility in organic solvents like ethanol or chloroform.
  • Degree of Ionization: The carboxylic acid group could ionize in aqueous solutions at physiological pH, which may significantly improve its solubility in water, depending on the specific conditions.
  • Interactions with Solvents: Solubility may also be influenced by the temperature and the presence of cosolvents or surfactants, which can modify the solvent-solute interactions.

In conclusion, while it may exhibit some degree of solubility in various environments, the overall solubility of 13-acetoxy-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-14-tridecanoyloxy-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-diene-8-carboxylic acid is likely complex, reflecting a balance of its diverse functional groups and hydrocarbon nature.

Interesting facts

Interesting Facts about 13-acetoxy-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-14-tridecanoyloxy-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-diene-8-carboxylic acid

This remarkable compound, often referenced by its complex name, is a member of the larger family of terpenoids, which are biodiversity-rich natural products derived from plants. Here are some fascinating insights:

  • Natural Origins: Compounds of this nature are typically found in various plant species and can play crucial roles in plant defense mechanisms and signaling.
  • Biological Significance: It may have biological activities such as antifungal, antibacterial, or anticancer properties, making it a subject of interest for pharmacological studies.
  • Complex Structure: This compound features a tetracyclic structure, which indicates a unique three-dimensional arrangement. Such complexity can lead to interesting properties and behaviors, which scientists aim to understand thoroughly.
  • Green Chemistry: The synthesis pathways for compounds with intricate structures prompt research into eco-friendly methods of production, aligning with the principles of green chemistry that aim to minimize environmental impact.
  • Chemical Modifications: Due to the presence of functional groups like acetoxy and hydroxy, there’s a vast scope for chemical modifications, offering potential for the synthesis of derivatives with enhanced or altered biological activities.

In studying compounds like this, one can see the beauty of chemistry—not just in the intricate chemical formulas but also in the potential applications of these compounds across various fields, such as medicine, agriculture, and biochemistry. As a chemistry student or an enthusiast, exploring the rich chemical landscape of such compounds can reveal both the intricacies of nature and the innovative possibilities that arise from them.