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Piperonyl piperidone

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Identification
Molecular formula
C13H15NO3
CAS number
39742-60-4
IUPAC name
1,3-benzodioxol-5-yl(1-piperidyl)methanone
State
State

At room temperature, piperonyl piperidone is typically in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
39.50
Melting point (Kelvin)
312.65
Boiling point (Celsius)
298.00
Boiling point (Kelvin)
571.15
General information
Molecular weight
221.25g/mol
Molar mass
221.2530g/mol
Density
1.1432g/cm3
Appearence

Piperonyl piperidone appears as a white to off-white crystalline powder. It is typically odorless and possesses a slightly bitter taste.

Comment on solubility

Solubility of 1,3-benzodioxol-5-yl(1-piperidyl)methanone (C13H15NO3)

The solubility of 1,3-benzodioxol-5-yl(1-piperidyl)methanone presents some interesting characteristics that are worth discussing. This compound, with a chemical structure that features both aromatic and aliphatic components, may exhibit varying degrees of solubility depending on the solvent used.

Factors Influencing Solubility:

  • Polarity: The presence of the dioxole group suggests that this compound may have polar characteristics, potentially enhancing its solubility in polar solvents such as water or methanol.
  • Hydrogen Bonding: The amine group from the piperidine structure can participate in hydrogen bonding, which may further increase solubility in polar environments.
  • Structural Interactions: The overall molecular structure, including steric factors, can influence solubility. For example, bulky groups may impede solvation and lower solubility.

Typical Solubility Observations:

Compounds similar in structure often display the following solubility patterns:

  • Good solubility in organic solvents such as ethanol, chloroform, and acetone.
  • Moderate solubility in polar solvents, depending significantly on their specific interactions.
  • Limited solubility in non-polar solvents due to polar functional groups.

In conclusion, while the exact solubility of 1,3-benzodioxol-5-yl(1-piperidyl)methanone can vary, understanding the key factors that influence its behavior in different environments provides valuable insight into its potential applications and behavior in chemical formulations. Exploring these solubility characteristics further can enable researchers to predict its behavior in various chemical systems.

Interesting facts

1,3-Benzodioxol-5-yl(1-piperidyl)methanone: An Intriguing Compound

This compound, known as 1,3-benzodioxol-5-yl(1-piperidyl)methanone, is a fascinating member of the benzodioxole family, often studied in medicinal chemistry and pharmacology. Here are some notable facts about this compound:

  • Structural Elements: The unique structure of this compound features a benzodioxole ring paired with a piperidine moiety. This combination confers interesting properties that can be leveraged in various chemical applications.
  • Pharmacological Interest: Compounds like 1,3-benzodioxol-5-yl(1-piperidyl)methanone can be significant in drug discovery, particularly in the realm of psychoactive substances. They can exhibit various effects on neurotransmitter systems.
  • Potential Uses: Research suggests that derivatives of this compound may have therapeutic potential against certain psychiatric disorders, due to their influence on serotonin and dopamine pathways.
  • Inspiration from Nature: The core structure is reminiscent of naturally occurring compounds found in plants, indicating how nature inspires synthetic chemistry.
  • Experimental Studies: Ongoing investigations focus on its synthesis and the exploration of its biological activity, with scientists keen to uncover the underlying mechanisms of action.
  • Caveats in Research: While the compound shows promise, careful study is required due to the potential for psychoactive effects, highlighting the importance of dosage and application in research.

In the world of chemistry, 1,3-benzodioxol-5-yl(1-piperidyl)methanone stands out not just for its interesting structure but also for the rich avenues of research it opens, making it a point of interest for both chemists and pharmacologists. As we continue to unravel the complexities of compounds like these, we pave the way for advancements in medicinal chemistry that could lead to new therapies and a better understanding of human biology.

Synonyms
1-BCP
34023-62-6
1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine
1,3-benzodioxol-5-yl(piperidin-1-yl)methanone
BA-14
Piperonylic acid piperidide
benzo[d][1,3]dioxol-5-yl(piperidin-1-yl)methanone
Piperidine, 1-(1,3-benzodioxol-5-ylcarbonyl)-
1-(2H-1,3-benzodioxole-5-carbonyl)piperidine
BA 14
BRN 0234640
N-(3,4-Methylenedioxybenzoyl)piperidine
AI3-01460
Tocris-1048
Biomol-NT_000223
Oprea1_018227
4-20-00-01340 (Beilstein Handbook Reference)
SCHEMBL244547
1-BCP?
BPBio1_001318
CHEMBL103469
DTXSID10187634
CHEBI:109531
HMS3267C12
HMS3412C13
HMS3676C13
BCP32589
JBA02362
s6803
STK296800
AKOS001335871
NCGC00024965-01
NCGC00024965-02
DA-59914
MS-23341
1-(1,3-dioxaindane-5-carbonyl)piperidine
HY-101363
CS-0021222
1,3-benzodioxol-5-yl(1-piperidinyl)methanone
1-(1,3-benzodioxol-5-yl-carbonyl)piperidine
F77822
Benzo[1,3]dioxol-5-yl-piperidin-1-yl-methanone
EN300-1700021
SR-01000597472
SR-01000597472-1
BRD-K25140590-001-01-4
BRD-K25140590-001-02-2
BRD-K25140590-001-03-0
Q27188679
Z31424194
F2299-0303
Piperonylic acid piperidide;1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine
InChI=1/C13H15NO3/c15-13(14-6-2-1-3-7-14)10-4-5-11-12(8-10)17-9-16-11/h4-5,8H,1-3,6-7,9H