Skip to main content

1,3-benzodioxole

ADVERTISEMENT
Identification
Molecular formula
C7H6O2
CAS number
274-09-9
IUPAC name
1,3-benzodioxole
State
State

1,3-Benzodioxole is in a liquid state at room temperature.

Melting point (Celsius)
-17.00
Melting point (Kelvin)
256.15
Boiling point (Celsius)
172.00
Boiling point (Kelvin)
445.15
General information
Molecular weight
122.12g/mol
Molar mass
122.1230g/mol
Density
1.3000g/cm3
Appearence

1,3-Benzodioxole is a colorless to pale yellow oily liquid. It often appears as a clear, mobile liquid at room temperature and is known for its aromatic odor, reminiscent of methylenedioxyphenyl fragrances.

Comment on solubility

Solubility of 1,3-benzodioxole

1,3-benzodioxole, with its unique aromatic structure, exhibits interesting solubility properties that are influenced by its molecular characteristics. This compound is generally regarded as sparingly soluble in water, owing to its hydrophobic nature attributed to the benzene rings present in its structure.

When discussing its solubility characteristics, consider the following:

  • Solvents: 1,3-benzodioxole is much more soluble in organic solvents such as:
    • Chloroform
    • Ethanol
    • Ether
  • Temperature Influence: Like many organic compounds, its solubility in solvents can increase with temperature.
  • Hydrophobic Interactions: The presence of the dioxole group reduces its affinity for polar solvents, making it less soluble in aqueous environments.

As a result, the solubility of 1,3-benzodioxole must be carefully considered when selecting solvents for chemical reactions or extractions. It serves as a reminder that understanding solubility is crucial for applications in organic chemistry, where the choice of solvent can significantly influence reaction outcomes.

Interesting facts

Interesting Facts About 1,3-Benzodioxole

1,3-Benzodioxole is a fascinating organic compound that has captured the interest of chemists and industry professionals alike due to its unique structure and properties. Here are some intriguing points about this compound:

  • Structural Features: The compound features a fused ring structure that consists of a benzene ring connected to a dioxole. This distinctive architecture allows it to exhibit various biological and chemical activities.
  • Biological Significance: Research has shown that compounds related to 1,3-benzodioxole have potential pharmacological properties. They may exhibit activities such as anti-inflammatory, anticancer, and antimicrobial effects, making them of interest in drug discovery.
  • Natural Occurrence: This compound is found in nature, particularly in certain plants. It has been isolated from sources such as Aristolochia species, which are known for their medicinal uses.
  • Applications: Beyond its biological importance, 1,3-benzodioxole is also utilized in the synthesis of various synthetic materials, flavors, and fragrances due to its appealing aromatic properties.
  • Reactivity: The presence of electron-donating and electron-withdrawing groups in its structure makes it a versatile starting material for various chemical reactions, including nucleophilic substitutions and cycloadditions.

With its potential applications in medicine and materials science, 1,3-benzodioxole continues to be a subject of active research. As chemists explore its properties and derivatives, we can anticipate discovering even more exciting uses for this compound!

Synonyms
1,3-BENZODIOXOLE
274-09-9
Benzo[d][1,3]dioxole
1,2-Methylenedioxybenzene
Benzodioxole
1,2-(Methylenedioxy)benzene
1,3-Dioxaindan
3,4-Methylenedioxybenzene
2H-1,3-Benzodioxole
1,3-Dioxindan
Methylenedioxybenzene
o-(Methylenedioxy)benzene
1,3-Benzodioxolane
NSC 30095
o-Methylenedioxybenzene
(Methylenedioxy)benzene
EINECS 205-992-0
1.3-benzodioxole
UNII-F0XLL582B8
Benzene, 1,2-(methylenebis(oxy))-
Benzene, 1,2-methylenedioxy-
BRN 0115506
AI3-30574
Benzene, 1,2-(methylenedioxy)-
MFCD00005818
NSC-30095
F0XLL582B8
CHEMBL4757380
DTXSID9051951
CHEBI:38732
EC 205-992-0
5-19-01-00434 (Beilstein Handbook Reference)
2H-BENZO(D)-1,3-DIOXOLANE
Benzene, 1,2-[methylenebis(oxy)]-
benzo[1,3]dioxole
benzodioxolan
1,3-dioxaindane
1,3Dioxaindan
1,3Benzodioxolane
1,3Dioxindan
benzo[1,3]dioxol
benzo[1.3]dioxol
2H1,3Benzodioxole
o(Methylenedioxy)benzene
1,2methylenedioxybenzene
3,4methylenedioxybenzene
1,2-methylenedioxy-benzene
1,3-Benzodioxole (1,2-Methylenedioxybenzene)
Benzene, 1,2methylenedioxy
SCHEMBL8711
1,3-Benzodioxole, 99%
ghl.PD_Mitscher_leg0.1027
SCHEMBL5176793
WLN: T56 BO DO CHJ
DTXCID2030514
Benzene,2-[methylenebis(oxy)]-
CHEBI:38733
Benzene, 1,2(methylenebis(oxy))
BCP11873
NSC30095
BDBM50595121
AKOS000441921
CS-W020572
FB02566
AS-18932
DB-027320
M0658
NS00020781
EN300-21045
D70968
Q3544944
F1908-0058