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piperonylic acid

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Identification
Molecular formula
C8H6O4
CAS number
94-53-1
IUPAC name
1,3-benzodioxole-5-carboxylic acid
State
State

Piperonylic acid is typically found in the solid state at room temperature, appearing as crystalline powder formed into flakes or granules, and is stable under normal conditions of use.

Melting point (Celsius)
229.00
Melting point (Kelvin)
502.15
Boiling point (Celsius)
323.00
Boiling point (Kelvin)
596.15
General information
Molecular weight
166.13g/mol
Molar mass
166.1450g/mol
Density
1.4800g/cm3
Appearence

Piperonylic acid appears as a white to off-white crystalline powder. The compound is typically odorless. It may form elongated crystals depending on the method of crystallization.

Comment on solubility

Solubility of 1,3-benzodioxole-5-carboxylic Acid

1,3-benzodioxole-5-carboxylic acid, a unique organic compound, exhibits intriguing solubility characteristics that are worth noting. Generally, the solubility of a compound can be influenced by various factors, including polarity, temperature, and the presence of other solvents. For this specific compound, the following points summarize its solubility behavior:

  • Solvent Dependence: 1,3-benzodioxole-5-carboxylic acid is known to dissolve well in polar solvents such as water and ethanol, making it versatile for chemical applications.
  • Temperature Influence: The solubility tends to increase with rising temperatures, which is a common phenomenon in many organic acids.
  • pH Sensitivity: As a carboxylic acid, its solubility can vary with pH; higher solubility is often observed in more alkaline conditions due to the deprotonation of the carboxyl group.
  • Hydrogen Bonding: The presence of functional groups allows for significant hydrogen bonding with solvents, further enhancing solubility.

Overall, understanding the solubility profile of 1,3-benzodioxole-5-carboxylic acid is crucial for applications in organic synthesis and pharmaceutical development. As it is often stated, "Like dissolves like"—thus its polar nature allows it to associate favorably with polar solvents, enhancing its utility in various chemical processes.

Interesting facts

Interesting Facts about 1,3-benzodioxole-5-carboxylic Acid

1,3-benzodioxole-5-carboxylic acid, a fascinating compound, is often studied in the realm of organic chemistry due to its unique structural properties and potential applications. Below are some intriguing aspects of this compound:

  • Structure & Stability: The compound features a benzodioxole core, which is notable for its fused ring system comprising two dioxole rings incorporated into a benzene ring. This distinct arrangement contributes to its chemical stability and reactivity.
  • Biological Relevance: Research indicates that derivatives of 1,3-benzodioxole-5-carboxylic acid have shown potential as therapeutic agents. They are being explored for their biological activities, including anti-inflammatory and antioxidant properties.
  • Synthesis Versatility: The compound can be synthesized through various methods, including oxidation reactions and condensation processes. These synthetic routes allow chemists to explore a wide range of substituents, giving rise to numerous derivatives with varying properties.
  • Applications in Material Science: Compounds related to 1,3-benzodioxole have been explored for their role in developing new materials. These applications could range from organic electronics to advanced polymers.
  • Novel Derivatives: Researchers are constantly synthesizing new analogs of this compound, examining how changes in molecular structure can enhance specific properties or functional applications.

In summary, 1,3-benzodioxole-5-carboxylic acid is not just an ordinary compound; it embodies a rich area of study in chemistry. Its unique structure and promising biological and material science applications make it a vital subject for ongoing research and innovation. This compound exemplifies the intricate connection between molecular structure and functional potential, highlighting the depth of exploration possible within organic chemistry.

Synonyms
PIPERONYLIC ACID
94-53-1
1,3-Benzodioxole-5-carboxylic acid
Benzo[d][1,3]dioxole-5-carboxylic acid
Heliotropic acid
3,4-Methylenedioxybenzoic acid
Protocatechuic acid methylene ether
benzo[1,3]dioxole-5-carboxylic acid
3,4-(Methylenedioxy)benzoic acid
2H-1,3-Benzodioxole-5-Carboxylic Acid
5-Benzodioxolecarboxylic acid
MFCD00005830
3,4-Dioxymethylenebenzoic acid
3,4-Methylene dioxybenzoic acid
NSC 10072
Benzoic acid, 3,4-(methylenedioxy)-
QX3V1NO0KH
EINECS 202-342-8
AI3-05972
NSC-10072
PIPERONYLIC ACID [MI]
DTXSID6059104
CHEBI:107644
1,3-dioxaindane-5-carboxylic acid
PIPERONYLIC ACID-2,2-D2
benzo(d)(1,3)dioxole-5-carboxylic acid
UNII-QX3V1NO0KH
piperonylsaure
4ddk
0HN
Spectrum_001164
Piperonylic acid, 99%
Spectrum3_001022
Spectrum4_001152
5Benzodioxolecarboxylic acid
5-carboxy-1,3-benzodioxole
BSPBio_002803
KBioGR_001723
KBioSS_001644
SPECTRUM500580
3,4Dioxymethylenebenzoic acid
SCHEMBL142318
3,4Methylene dioxybenzoic acid
CHEMBL573781
1,3Benzodioxole5carboxylic acid
PIPERONYLIC ACID [INCI]
3,4-methylenedioxy-benzoic acid
DTXCID7048902
KBio2_001644
KBio2_004212
KBio2_006780
KBio3_002023
VDVJGIYXDVPQLP-UHFFFAOYSA-
Benzoic acid,4-(methylenedioxy)-
BDBM153299
benzoic acid, 3,4-methylenedioxy-
3, 4-(Methylenedioxy)benzoic acid
3,4-(Methylenedioxy)-Benzoic acid
Benzoic acid, 3,4(methylenedioxy)
CS-D1455
NSC10072
STR05605
BBL011979
STK397540
1,3-Benzodioxole -5-carboxylic acid
1,3-benzodioxole-5-carbonsäure
AKOS000113163
benzo[1,3]-dioxole-5-carboxylic acid
BS-3899
CCG-214272
FB34327
PB47803
SDCCGMLS-0065919.P001
SDCCGMLS-0065919.P002
Benzo[d][1,3]dioxole-5-carboxylicacid
Benzo[d][I,3]dioxole-5-carboxylic acid
NCGC00095970-01
NCGC00095970-02
AC-11342
HY-41404
SY004612
1,3-Benzodioxole-5-carboxylic acid, 9CI
Piperonylic acid, purum, >=97.0% (T)
DB-011499
NS00040406
P0459
EN300-20111
F16336
3,4-(Methylenedioxy)benzoic acid;Piperonylic acid
AE-562/40258182
BRD-K52148119-001-01-5
BRD-K52148119-001-02-3
Q27185967
F3318-0150
Z104476884
3,4-Methylenedioxybenzoic acid; 1,3-Benzodioxole-5-carboxylic acid
InChI=1/C8H6O4/c9-8(10)5-1-2-6-7(3-5)12-4-11-6/h1-3H,4H2,(H,9,10)
202-342-8