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2-Aminobenzothiazole

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Identification
Molecular formula
C7H6N2S
CAS number
136-95-8
IUPAC name
1,3-benzothiazol-2-amine
State
State

At room temperature, 2-Aminobenzothiazole is in a solid state, typically appearing as a crystalline powder.

Melting point (Celsius)
107.00
Melting point (Kelvin)
380.15
Boiling point (Celsius)
321.00
Boiling point (Kelvin)
594.15
General information
Molecular weight
150.21g/mol
Molar mass
150.2080g/mol
Density
1.3800g/cm3
Appearence

The compound 2-Aminobenzothiazole appears typically as white to pale yellow crystalline powder.

Comment on solubility

Solubility of 1,3-benzothiazol-2-amine

1,3-benzothiazol-2-amine, a compound featuring a benzothiazole core, exhibits unique solubility characteristics that can vary depending on the solvent used. Understanding its solubility is essential for applications in pharmaceuticals and materials science.

Solubility Profile

The solubility of 1,3-benzothiazol-2-amine can be summarized as follows:

  • Water: This compound typically shows poor solubility in water, which often limits its use in aqueous environments.
  • Organic Solvents: It has a higher solubility in various organic solvents, such as:
    • Dimethyl sulfoxide (DMSO)
    • Ethyl acetate
    • Tetrahydrofuran (THF)
  • pH Sensitivity: The solubility may be affected by the pH of the solution, with variations noted in acidic or basic conditions.

"Like many organic compounds, the solubility of 1,3-benzothiazol-2-amine is influenced by factors such as temperature, ionic strength, and molecular interactions." This complexity calls for careful consideration in synthetic applications and formulations.

Conclusion

Overall, while 1,3-benzothiazol-2-amine is not highly soluble in water, it can be effectively dissolved in a variety of organic solvents, enabling its use in applications where such solubility is required. Understanding these properties is crucial for exploiting its full potential in scientific research and industrial applications.

Interesting facts

Interesting Facts About 1,3-Benzothiazol-2-amine

1,3-Benzothiazol-2-amine is a fascinating compound that belongs to the class of benzothiazoles, which are known for their diverse applications in various fields of chemistry and industry. Here are some intriguing aspects of this compound:

  • Structure & Benefits: The unique structure of 1,3-benzothiazol-2-amine, characterized by a fused benzene and thiazole ring, gives it notable chemical properties that make it useful in various biochemical settings.
  • Pharmaceutical Applications: Compounds like 1,3-benzothiazol-2-amine have been investigated for their potential roles as pharmaceutical agents. Some derivatives exhibit antimicrobial and anti-inflammatory activity, making them of significant interest in drug discovery.
  • Fluorescent Properties: This compound can serve as a precursor for the synthesis of fluorescent dyes, which are invaluable in biological imaging and diagnostics. This feature makes it attractive for researchers in the field of fluorescence microscopy.
  • Research Tool: The thiazole moiety in this compound is also a key feature in many research studies, as it can be utilized in the synthesis of various organic reactions providing researchers with essential insights into chemical behavior.
  • Environmental Impact: Understanding compounds like 1,3-benzothiazol-2-amine is crucial in assessing environmental pollution, as some benzothiazole derivatives have been detected in water systems, raising questions about their ecological effects.

In summary, the compound 1,3-benzothiazol-2-amine stands out not only for its unique structural characteristics but also for its wide range of applications in science and industry. Whether it’s its role in drug development or its significance in environmental monitoring, this compound continues to intrigue researchers and students alike.

Synonyms
2-AMINOBENZOTHIAZOLE
136-95-8
benzo[d]thiazol-2-amine
2-Benzothiazolamine
1,3-Benzothiazol-2-amine
Benzothiazol-2-ylamine
2-Aminobenzthiazole
Benzothiazole, 2-amino-
2-Iminobenzothiazoline
o-Aminobenzothiazole
2-Benzothiazolylamine
102337-98-4
2(3H)-Benzothiazolimine
2-Amino-benzothiazole
USAF XR-27
NSC 4670
USAF EK-3941
2-amino-1,3-benzothiazol
2-Amino-1,3-benzothiazole
HSDB 2741
EINECS 205-268-4
08K5TLY3EQ
DTXSID1024467
AI3-52249
NSC-4670
Benzothiazole-2-ylamine
AMINOBENZOTHIAZOLE, 2-
CHEMBL329785
DTXCID804467
2-Benzothiazolamine, homopolymer
2-AMINOBENZOTHIAZOLE [MI]
2-AMINOBENZOTHIAZOLE [HSDB]
MFCD00005785
2-aminobenzothiazol
UNII-08K5TLY3EQ
aminobenzothiazole
ABTS impurity
2aminobenzthiazole
2Benzothiazolamine
3mhw
oAminobenzothiazole
iminobenzothiazoline
benzothiazolyl-amine
2Benzothiazolylamine
ABV
2Iminobenzothiazoline
2-amino benzthiazole
Benzothiazole, 2amino
2(3H)Benzothiazolimine
2-Aminobenzothiazole, 6
MU-AMINOBENZTHIAZOLE
2-amino-1,3-benzthiazole
2NH2-BTH
Cambridge id 5108799
2-Aminobenzothiazole, 97%
1,3-benzothiazol-2-ylamine
SCHEMBL75245
84293-42-5
MLS002415693
BIDD:GT0339
1,3-Benzothiazol-2-amine #
SCHEMBL4511001
WLN: T56 BN DSJ CZ
1,3-benzothiazol-2(3H)-imine
NSC4670
4b34
CHEBI:167751
HMS1577K04
HMS3039J05
BCP26554
STR00404
Tox21_200818
BDBM50335100
CL4537
STL139201
STL186134
AKOS000119893
AKOS016368231
CS-W018140
FA10791
FS-3142
HY-W017424
SB18592
NCGC00091895-01
NCGC00091895-02
NCGC00258372-01
BP-21206
CAS-136-95-8
SMR001370883
DB-027802
A0277
NS00010260
EN300-17296
2-Benzothiazolamine,labeled with deuterium(9ci)
A15214
AE-848/01007013
Q27236407
Z56912586
F1386-0409
Cerium(III) Ionophore, Selectophore(TM), function tested
205-268-4