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Isatoic anhydride

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Identification
Molecular formula
C8H5NO3
CAS number
118-48-9
IUPAC name
1,3-benzoxazine-2,4-dione
State
State

Isatoic anhydride is usually found as a solid at room temperature.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.00
Boiling point (Celsius)
440.85
Boiling point (Kelvin)
714.00
General information
Molecular weight
163.13g/mol
Molar mass
163.1420g/mol
Density
1.4387g/cm3
Appearence

It appears as a white to off-white crystalline powder. The compound is typically very fine and can have a slightly yellowish tint depending on purity.

Comment on solubility

Solubility of 1,3-benzoxazine-2,4-dione

1,3-benzoxazine-2,4-dione, often encountered in various chemical and therapeutic applications, displays specific solubility characteristics that are noteworthy:

  • Polar Solvents: This compound tends to show better solubility in polar solvents like water and methanol. The presence of functional groups can enhance its interaction with polar molecules, facilitating better dissolution.
  • Non-Polar Solvents: Conversely, 1,3-benzoxazine-2,4-dione's solubility in non-polar solvents such as hexane or benzene is considerably lower. This is due to weaker interactions between the largely polar compound and non-polar solvent molecules.
  • pH Sensitivity: The solubility might also vary with pH changes; for instance, an increase in acidity can sometimes improve the solubility of compounds with acidic sites.

As with many organic compounds, factors such as temperature, pressure, and molecular structure play crucial roles in determining solubility. It's essential to consider these factors when attempting to dissolve 1,3-benzoxazine-2,4-dione in different environments.

Understanding the solubility behavior of 1,3-benzoxazine-2,4-dione is vital for its effective utilization in various chemical processes and applications.

Interesting facts

Interesting Facts About 1,3-benzoxazine-2,4-dione

1,3-benzoxazine-2,4-dione, often recognized for its unique bicyclic structure, belongs to a class of organic compounds that has garnered significant attention in the fields of organic chemistry and materials science.

Chemical Properties and Applications

This compound is known for:

  • Versatile Reactivity: It can participate in various chemical reactions, making it a valuable intermediate in organic synthesis.
  • Biological Activity: Some derivatives of 1,3-benzoxazine-2,4-dione have demonstrated potential as anti-cancer agents and anti-inflammatory agents, showcasing its importance in medicinal chemistry.
  • Material Science: The compound has promising applications in polymer chemistry, particularly in developing new materials with desired thermal and mechanical properties.

Unique Structural Features

The distinct structure of 1,3-benzoxazine-2,4-dione contributes to its intriguing properties:

  • Heterocyclic Ring System: The presence of both carbon and oxygen atoms in the ring system enhances its chemical stability.
  • Position of Functional Groups: The positioning of the carbonyl groups affects its reactivity and interaction with other chemical species.

Environmental and Safety Considerations

As with many chemical compounds, handling 1,3-benzoxazine-2,4-dione safely is crucial. Proper laboratory practices should be followed to mitigate any health risks associated with its use.

In summary, 1,3-benzoxazine-2,4-dione serves as an excellent example of how a simple molecule can have diverse applications in various scientific domains. Its rich chemistry continues to inspire research and innovation.

Synonyms
Carsalam
2037-95-8
2H-1,3-BENZOXAZINE-2,4(3H)-DIONE
Beaprine
1,3-Benzoxazine-2,4-dione
Ruhmal
Oxophenhydroxazine
Oxobenzhydroxazin
Oxophenhydroxazin
Carsalamo
Carsalamum
Carsalamum [INN-Latin]
Carsalamo [INN-Spanish]
Carsalam [INN:BAN:DCF]
NSC 36166
NSC-36166
4H-1,3-Benzoxazine-2,4(3H)-dione
BRN 0136767
DTXSID3046584
OXYPHENHYDRAZINE
AI3-25161
685H843ULU
CARSALAM [INN]
CARSALAM [MI]
DTXCID1026584
4-27-00-03326 (Beilstein Handbook Reference)
Carsalamum (INN-Latin)
Carsalamo (INN-Spanish)
2H-1,3-benzoxazin-4(3H)-one
606-541-4
2H-Benzo[e][1,3]oxazine-2,4(3H)-dione
3,4-dihydro-2H-1,3-benzoxazine-2,4-dione
MFCD00600566
NCGC00166265-01
CAS-2037-95-8
SR-01000392668
UNII-685H843ULU
2H-1,4(3H)-dione
4H-1,4(3H)-dione
SCHEMBL26521
MLS001249437
CHEMBL1720051
SCHEMBL17844931
CHEBI:134794
HMS3264N17
Pharmakon1600-01504504
HY-B1047
NSC36166
Tox21 112383
Tox21_112383
NSC758885
s4555
AKOS015917497
Tox21_112383_1
CCG-213935
CS-4568
FB45734
FD10735
NSC-758885
NCGC00166265-02
AS-10042
DA-51595
SMR000718659
SY110608
SBI-0207074.P001
2-hydroxy-4h-benzo[e][1,3]oxazin-4-one
4-hydroxy-2h-benzo[e][1,3]oxazin-2-one
EU-0067206
NS00026608
2H-1,3-Benzoxazine-2,4(3H)-dione, 98%
EN300-330999
AB00632416_03
AJ-333/25006179
SR-01000392668-1
SR-01000392668-2
BRD-K13238618-001-01-8
BRD-K13238618-001-05-9
Q27264215
Z1255365144
InChI=1/C8H5NO3/c10-7-5-3-1-2-4-6(5)12-8(11)9-7/h1-4H,(H,9,10,11
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