N,N'-bis(3,5-bis(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea

Identification

Molecular formula

C₂₇H₃₀N₁₀O

CAS number

150675-48-4

IUPAC name

1,3-bis[3,5-bis(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea

State

At room temperature, this compound is typically found as a solid.

Melting point (Celsius)

360.00

Melting point (Kelvin)

633.15

Boiling point (Celsius)

718.00

Boiling point (Kelvin)

991.15

General information

Molecular weight

456.54g/mol

Molar mass

456.5410g/mol

Density

1.3000g/cm³

Appearence

This compound appears as a white to off-white solid, usually in powdered form. It is sparingly soluble in water but may dissolve in organic solvents, such as dimethyl sulfoxide (DMSO) or dimethylformamide (DMF).

Comment on solubility

Solubility of 1,3-bis[3,5-bis(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea

The solubility of 1,3-bis[3,5-bis(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea in various solvents can be quite intriguing due to its complex structure. Here are some key points to consider:

Polarity: The presence of multiple imidazole and urea functional groups suggests that the compound may exhibit amphiphilic characteristics, potentially leading to varying solubility in polar and non-polar solvents.
Solvent Effects: Its solubility might be higher in polar aprotic solvents such as DMSO (Dimethyl sulfoxide) or DMF (Dimethylformamide) compared to non-polar solvents.
Hydrogen Bonding: The formation of hydrogen bonds with solvent molecules can significantly impact solubility. The ability to donate and accept hydrogen bonds might enhance its solubility in water to some extent.
pH Dependency: Solubility might vary with pH, particularly since imidazole derivatives can exhibit different ionization states based on the acidity or basicity of the solution.

In summary, while 1,3-bis[3,5-bis(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea may not be highly soluble in water, its solubility can be significantly influenced by the choice of solvent and environmental conditions. It is essential to conduct experimental determinations to accurately assess solubility characteristics in practical applications.

Interesting facts

Interesting Facts about 1,3-bis[3,5-bis(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea

1,3-bis[3,5-bis(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea is a fascinating compound that captures the interest of chemists due to its unique structure and potential applications. Here are some intriguing points about this compound:

Complex Structure: The compound features a central urea group flanked by two bulky 3,5-bis(4,5-dihydro-1H-imidazol-2-yl)phenyl groups. This arrangement provides a rich field for exploring steric and electronic effects in molecular interactions.
Potential Applications: Research indicates that similar compounds may have significant applications in medicinal chemistry, particularly as antitumor agents or in the development of novel pharmaceuticals due to their ability to interact with biological targets.
Hybrid Functionality: The incorporation of the imidazole ring in its structure brings forth unique properties, including enhanced interactions with metal ions, which might be attractive for catalysis or as sensors.
Research Interest: Compounds of this nature have been the subject of various studies examining their synthesis and characterization, highlighting their importance in fields such as supramolecular chemistry and materials science.
Precursor Utility: The building blocks for creating similar compounds often stem from commonly available materials, making synthesis more accessible for researchers and thus increasing their appeal in both academic and industrial settings.

In summary, 1,3-bis[3,5-bis(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea exemplifies the intricate interplay between structure and function within organic chemistry. As the scientific community continues to explore its properties and potential applications, it stands as a testament to the creativity and innovation inherent in chemical research.

Synonyms

CHEMBL2420210

SCHEMBL17793371