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Phenobarbital

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Identification
Molecular formula
C12H12N2O3
CAS number
50-06-6
IUPAC name
1,3-bis[4-(diethylamino)but-2-ynyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, phenobarbital is in a solid state as a crystalline powder.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
232.24g/mol
Molar mass
232.2300g/mol
Density
1.2700g/cm3
Appearence

Phenobarbital appears as a white, odorless, crystalline powder that is often tasteless and stable in air. It is sparingly soluble in water and soluble in alcohol and chloroform.

Comment on solubility

Solubility of 1,3-bis[4-(diethylamino)but-2-ynyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione

The solubility of 1,3-bis[4-(diethylamino)but-2-ynyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione in various solvents is a significant factor in its application and usage. Understanding its solubility can provide insights into its behavior in different environments. Here are some important points regarding its solubility:

  • Polar Solvents: Generally, compounds with extensive hydrophilic characteristics tend to dissolve well in polar solvents. However, due to the presence of diethylamino groups and aromatic systems, this compound might exhibit limited solubility in highly polar solvents.
  • Non-Polar Solvents: Expect good solubility in non-polar solvents like hexane or toluene, as the compound’s hydrophobic regions may interact favorably with these solvents.
  • Phrasing Considerations: As noted in various studies, "the larger and more complex the molecule, the more variations in solubility can be observed." Hence, the unique structure of this compound suggests that solubility will vary significantly under different conditions.
  • Temperature Dependence: Solubility can also be affected by temperature, as increased thermal energy typically enhances the dissolution ability of solids.

In conclusion, while the exact solubility profile of 1,3-bis[4-(diethylamino)but-2-ynyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione may vary depending on the solvent, it stands to reason that a careful approach in selecting solvents will be required to utilize this compound effectively. Scientists are encouraged to conduct empirical solubility tests to determine compatibility with desired solvents.

Interesting facts

Interesting Facts about 1,3-bis[4-(diethylamino)but-2-ynyl]-5-ethyl-5-phenyl-hexahydropyrimidine-2,4,6-trione

This fascinating compound belongs to the class of hexahydropyrimidine derivatives, which are recognized for their diverse biological activities. Here are some intriguing points to consider:

  • Versatile Applications: Due to its unique structure, this compound has potential applications in various fields including pharmaceuticals and material science.
  • Biological Impact: Compounds with similar structures have been noted for their *antimicrobial* properties as well as their role in *antioxidant* activity, opening avenues for research in medicinal chemistry.
  • Synthetic Pathways: The synthesis of this compound involves complex organic reactions, often requiring expertise in multi-step synthesis techniques, highlighting the creativity and precision needed in organic chemistry.
  • Zwitterionic Nature: Its ability to exhibit zwitterionic behavior (having both positive and negative charges) can influence its solubility and reactivity, affecting its usability in diverse applications.
  • Research Potential: As scientists continue to explore the properties of such compounds, they may uncover new *therapeutic agents* that can combat diseases or enhance the efficacy of existing drugs.

With its intricate molecular design, this compound serves as a remarkable example of how specific modifications at the molecular level can lead to significant variations in chemical properties and biological functions.

In the words of renowned chemists, “*The beauty of chemistry lies in the subtle balance between structure and function.*” This statement underscores the importance of studying compounds like this to fully understand their potential.