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Oxazepam

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Identification
Molecular formula
C15H11ClN2O2
CAS number
145-13-1
IUPAC name
1,3-bis[4-(diethylamino)but-2-ynyl]-5,5-diethyl-hexahydropyrimidine-2,4,6-trione;dihydrochloride
State
State

At room temperature, oxazepam is in a solid state, appearing typically as a crystalline powder. It is stable and does not react with air or moisture under normal conditions. The solid form is convenient for its primary use in tablet and capsule formulations for medicinal purposes.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.15
Boiling point (Celsius)
385.00
Boiling point (Kelvin)
658.15
General information
Molecular weight
286.71g/mol
Molar mass
286.7270g/mol
Density
1.4000g/cm3
Appearence

Oxazepam typically appears as a white to off-white crystalline powder. It is characterized by its inability to dissolve readily in water, although it is more soluble in organic solvents such as methanol and ethanol, which is typical for many benzodiazepines.

Comment on solubility

Solubility of 1,3-bis[4-(diethylamino)but-2-ynyl]-5,5-diethyl-hexahydropyrimidine-2,4,6-trione; dihydrochloride

The solubility of the compound 1,3-bis[4-(diethylamino)but-2-ynyl]-5,5-diethyl-hexahydropyrimidine-2,4,6-trione; dihydrochloride can be influenced by several factors, making its behavior in different environments quite interesting. Here are some key points regarding its solubility:

  • Form: As a dihydrochloride salt, the compound is likely to exhibit improved solubility in aqueous solutions compared to its free base form. This is a common characteristic observed in many organic compounds.
  • Polarity: The presence of multiple functional groups, particularly the diethylamino groups, adds to the compound's polarity. This typically enhances its solubility in polar solvents, such as water.
  • Temperature Dependency: Like many compounds, solubility can vary with temperature. As temperature increases, it might be expected that solubility also increases, allowing for more effective dissolution.
  • pH Effect: The solubility of this compound may be significantly affected by the pH of the solution. Adjusting the pH can help in optimizing solubility, particularly with amine-containing compounds which can be protonated.

In summary, the solubility characteristics of this compound highlight the interplay between its ionic nature and the structural features arising from its complex arrangement. Understanding these factors is crucial for applications where solubility plays a key role.

Interesting facts

Interesting Facts about 1,3-bis[4-(diethylamino)but-2-ynyl]-5,5-diethyl-hexahydropyrimidine-2,4,6-trione; dihydrochloride

This compound is a remarkable example of a synthetic organic molecule that presents striking properties and applications within the field of chemistry and pharmacology.

Structure and Functionality

The intricate structure of this compound includes several notable features:

  • Multi-functional Groups: The inclusion of diethylamino groups contributes to its potential basicity and reactivity.
  • Hexahydropyrimidine Framework: This cyclic structure plays a critical role in establishing the compound's pharmacological properties.
  • Availability of Reactive Sites: The presence of multiple functional groups provides a platform for further chemical reactions and modifications.

Potential Applications

This compound's unique design suggests various applications:

  • Pharmaceutical Use: The versatility in its structure allows it to be explored as a candidate for drug development, particularly in treating conditions that respond to changes in nucleobase activity.
  • Research Tool: It may serve as a probe in biological studies aimed at understanding cellular processes involving pyrimidine derivatives.
  • Material Science: Its synthetic pathways can also be investigated for creating novel polymeric materials due to the stability imparted by the hexahydropyrimidine framework.

Quote to Consider

As the great chemist Linus Pauling once said, "Science is a search for understanding." This compound, with its complex structure, epitomizes the continuous quest for innovation in chemical research.

Conclusion

In summary, 1,3-bis[4-(diethylamino)but-2-ynyl]-5,5-diethyl-hexahydropyrimidine-2,4,6-trione; dihydrochloride stands as a testament to the ingenuity of organic synthesis. Its unique properties and potential applications make it a subject of interest for both scientists and students eager to explore the frontiers of chemical knowledge.

Synonyms
Barbituric acid, 1,3-bis(4-(diethylamino)-2-butynyl)-5,5-diethyl-, dihydrochloride
3919-70-8
DTXSID50192429
1,3-Bis(4-(diethylamino)-2-butynyl)-5,5-diethylbarbituric acid dihydrochloride
5,5-Diethyl-1,3-bis(4-diethylamino-2-butynyl)barbituric acid dihydrochloride
DTXCID10114920