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Dantrolene

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Identification
Molecular formula
C14H10N4O
CAS number
7261-97-4
IUPAC name
1,3-bis[4-(N-guanidino-C-methyl-carbonimidoyl)phenyl]urea
State
State

At room temperature, dantrolene is in the form of a solid powder. It is not easily soluble in water, which can pose challenges during formulation for therapeutic use.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
314.27g/mol
Molar mass
314.2730g/mol
Density
1.2850g/cm3
Appearence

Dantrolene is an orange powder that is practically insoluble in water. It is usually presented in the form of capsules containing the powdered drug.

Comment on solubility

Solubility of 1,3-bis[4-(N-guanidino-C-methyl-carbonimidoyl)phenyl]urea

The solubility of 1,3-bis[4-(N-guanidino-C-methyl-carbonimidoyl)phenyl]urea is an intriguing aspect of this compound that reveals much about its chemical behavior. Understanding the solubility properties can help predict its interactions in various environments. Here are some key points regarding its solubility:

  • Polarity: This compound contains multiple functional groups such as urea and guanidine, which contribute to its overall polarity. Generally, polar compounds tend to be soluble in polar solvents.
  • Solvent Interactions: It is likely to be more soluble in water or other polar solvents due to hydrogen bonding and dipole-dipole interactions.
  • pH Sensitivity: The solubility may vary with pH, as changes in acidity or basicity can affect the ionization of the guanidino groups, enhancing solubility in certain conditions.
  • Temperature Effects: Increased temperature often increases solubility for many solids; hence, this compound might exhibit greater solubility at elevated temperatures.

In summary, while the exact solubility of 1,3-bis[4-(N-guanidino-C-methyl-carbonimidoyl)phenyl]urea is not universally established, its solubility is expected to be influenced by its polar nature, solvent choice, pH levels, and temperature. This multifaceted behavior underscores the compound's importance in various chemical applications.

Interesting facts

Interesting Facts about 1,3-bis[4-(N-guanidino-C-methyl-carbonimidoyl)phenyl]urea

The compound 1,3-bis[4-(N-guanidino-C-methyl-carbonimidoyl)phenyl]urea showcases some fascinating properties and applications, making it an intriguing subject of study in the field of chemistry.

Unique Characteristics

  • Altering Biological Activity: This compound has drawn attention for its potential role as a bioactive molecule, particularly in biomedical applications. Its structure may provide insights into designing novel therapeutics.
  • Multi-Functional Capability: With the presence of guanidine groups, this compound is posited to have diverse interactions within biological systems, contributing to various biochemical pathways.
  • Research Interest: It has been studied for its possible interactions with protein targets, making it valuable in drug discovery and development.

Application Areas

  • Medical Research: The guanidinium moiety is of specific interest as it often enhances the therapeutic potential of compounds through improved target affinity.
  • Chemistry and Material Science: Compounds similar to this may be utilized in the design of new materials, such as polymeric substances with tailored properties.

In summary, 1,3-bis[4-(N-guanidino-C-methyl-carbonimidoyl)phenyl]urea is more than just a chemical compound; it represents the crossroads of organic synthesis and biochemical innovation. As researchers continue to explore its applications, this compound may lead to breakthroughs in both medicine and materials science. Just remember the words of renowned chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas," encouraging continuous exploration within the realm of chemical compounds.

Synonyms
SCHEMBL13160507
DTXSID201138254
1,3-bis[4-[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]urea
Q22580451
2,2a(2)-[Carbonylbis(imino-4,1-phenyleneethylidyne)]bis[hydrazinecarboximidamide]