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1,3-Bis(dimethylamino)propan-2-ol

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Identification
Molecular formula
C7H18N2O
CAS number
6711-48-4
IUPAC name
1,3-bis(dimethylamino)propan-2-ol
State
State
1,3-Bis(dimethylamino)propan-2-ol is a liquid at room temperature, typically appearing as a faintly colored liquid with a noticeable amine odor.
Melting point (Celsius)
-32.00
Melting point (Kelvin)
241.15
Boiling point (Celsius)
213.00
Boiling point (Kelvin)
486.15
General information
Molecular weight
146.24g/mol
Molar mass
146.2370g/mol
Density
0.8900g/cm3
Appearence
1,3-Bis(dimethylamino)propan-2-ol is typically a colorless to pale yellow liquid with a slight amine-like odor. It is often used in its liquid form for various chemical applications.
Comment on solubility

Solubility of 1,3-bis(dimethylamino)propan-2-ol

1,3-bis(dimethylamino)propan-2-ol is known for its interesting solubility characteristics, which can be explained by its structural properties. As a quaternary ammonium compound, this compound features two dimethylamino groups that make it hydrophilic.

Here are some key points about its solubility:

  • Highly soluble in water: Given the presence of amino groups, which can engage in hydrogen bonding with water molecules, 1,3-bis(dimethylamino)propan-2-ol exhibits excellent solubility in aqueous solutions.
  • Solvent interactions: This compound tends to be more soluble in polar solvents compared to non-polar solvents due to its polar nature.
  • Concentration matters: The solubility can vary significantly with concentration and temperature, making it essential to consider specific conditions when working with this compound.

In summary, the solubility of 1,3-bis(dimethylamino)propan-2-ol is primarily influenced by its ability to form hydrogen bonds with water, enhancing its integration into polar environments. As a result, it serves various applications in aqueous solutions where solubility plays a critical role.

Interesting facts

Interesting Facts about 1,3-bis(dimethylamino)propan-2-ol

1,3-bis(dimethylamino)propan-2-ol is a fascinating compound that plays an important role in various scientific fields, particularly in organic chemistry and pharmaceuticals. Here are some highlights:

  • Dual Functionality: This compound is notable for its structure which includes two dimethylamino groups attached to a central propanol backbone. This unique arrangement can contribute to its properties as both a base and a nucleophile, making it versatile in chemical reactions.
  • Research Applications: It is commonly utilized in the synthesis of a variety of other compounds. The presence of the amino groups facilitates reactions where nucleophilic attack is required, allowing chemists to design complex molecules efficiently.
  • Pharmaceutical Relevance: Compounds like 1,3-bis(dimethylamino)propan-2-ol often serve as intermediates in the development of pharmaceutical agents. Their role in drug development cannot be overstated, as they can influence the bioavailability and pharmacokinetics of drug candidates.
  • Tuning Properties: The ability to modify the dimethylamino groups allows chemists to create derivatives that can be tailored for specific applications, enhancing the compound's solubility or its ability to permeate biological membranes.
  • Safety Considerations: As with many amines, it is important to handle this compound with caution. Familiarity with its potential hazards is essential for laboratory safety and best practices in research environments.
  • Future Directions: Ongoing research may uncover additional applications of this compound in areas such as materials science or catalysis, expanding its utility even further. The exploration of its properties continues to provoke interest in the scientific community.

Overall, 1,3-bis(dimethylamino)propan-2-ol exemplifies the complexity and versatility of organic compounds, underscoring the crucial intersection between structure and function in chemical science.

Synonyms
1,3-Bis(dimethylamino)-2-propanol
5966-51-8
2-PROPANOL, 1,3-BIS(DIMETHYLAMINO)-
EINECS 227-754-5
BRN 1446002
AI3-61598
1,3-Bis(dimethylamino)-2-hydroxypropane
DTXSID7064071
1,3-Bis(dimethylamino)isopropanol
4-04-00-01695 (Beilstein Handbook Reference)
DTXCID5042663
jgvzjrhazobpmw-uhfffaoysa-n
1,3-Bis(dimethylamino)propan-2-ol
[3-(dimethylamino)-2-hydroxypropyl]dimethylamine
SCHEMBL476608
CHEBI:229320
1,3-Bis-dimethylamino-propan-2-ol
AKOS002313501
AS-81198
FB149141
1,3-Bis(dimethylamino)-2-propanol, 97%
DB-008022
CS-0239030
NS00034214
G72658
EN300-2045066
N,N,N',N'-tetramethyl-2-hydroxy-1,3-propanediamine