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Dantrolene

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Identification
Molecular formula
C14H10N4O5
CAS number
7261-97-4
IUPAC name
1,3-bis(hydroxymethyl)-5,5-dimethyl-imidazolidine-2,4-dione
State
State

Dantrolene is typically found as a solid at room temperature.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.00
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.00
General information
Molecular weight
314.22g/mol
Molar mass
314.2160g/mol
Density
1.2650g/cm3
Appearence

Dantrolene is a yellow or orange crystalline powder. It is relatively insoluble in water and soluble in organic solvents like alcohols and chloroform.

Comment on solubility

Solubility of 1,3-bis(hydroxymethyl)-5,5-dimethyl-imidazolidine-2,4-dione

The solubility characteristics of 1,3-bis(hydroxymethyl)-5,5-dimethyl-imidazolidine-2,4-dione can be intriguing, particularly because of its unique structure. Here are some key points to consider regarding its solubility:

  • Polyhydroxyl Compounds: The presence of multiple hydroxymethyl groups generally enhances the solubility of organic compounds in water.
  • Hydrophilic Nature: This compound is likely to exhibit good solubility in polar solvents, especially water, due to the ability of hydroxyl groups to form hydrogen bonds.
  • Solvents: Solubility may vary significantly in different solvents; it could be less soluble in non-polar solvents.

In summary, you might find the solubility of 1,3-bis(hydroxymethyl)-5,5-dimethyl-imidazolidine-2,4-dione to be quite favorable in aqueous solutions, which is typical for many compounds possessing similar functional groups. As a rule of thumb, the more polar the solvent, the better the solubility for compounds of this nature.

Interesting facts

Interesting Facts about 1,3-bis(hydroxymethyl)-5,5-dimethyl-imidazolidine-2,4-dione

This intriguing compound, known as 1,3-bis(hydroxymethyl)-5,5-dimethyl-imidazolidine-2,4-dione, has garnered attention in various fields of research, particularly in the realm of medicinal chemistry. Here are some noteworthy points about this chemical:

  • Dual Functionality: The presence of multiple hydroxymethyl groups in its structure provides the compound with the ability to act as a versatile building block in the synthesis of other complex molecules.
  • Pharmaceutical Relevance: Compounds similar to this one are often investigated for their potential therapeutic properties, especially in drug design targeting specific biological pathways.
  • Chemical Stability: The imidazolidine ring structure offers a degree of stability that is crucial for compounds used in the development of pharmaceuticals, potentially leading to longer shelf lives and more effective medications.
  • Research Value: It serves as an important example in studies related to the modification of biomolecules, where researchers explore how structural changes can influence activity and interaction with biological systems.
  • Environmental Aspect: This compound also raises interest in discussions about sustainable chemistry, as its derivatives could be explored for use in environmentally friendly chemical processes.

As noted by a prominent chemist, "The real beauty of synthetic chemistry lies in understanding how each small change in a molecule can lead to significant variations in its properties and functions." This sentiment rings especially true for compounds like 1,3-bis(hydroxymethyl)-5,5-dimethyl-imidazolidine-2,4-dione, which continues to inspire chemists and researchers alike.

Synonyms
6440-58-0
DMDM Hydantoin
Dmdmh
Glydant
1,3-Bis(hydroxymethyl)-5,5-dimethylhydantoin
1,3-Dimethylol-5,5-dimethylhydantoin
Dantoin-DMDMH
Glycoserve-DMDMH
Dantoin dmdmh 55
Dimethylol-5,5-dimethylhydantoin
Dmdmh 55
Caswell No. 273AB
UNII-BYR0546TOW
EINECS 229-222-8
BYR0546TOW
EPA Pesticide Chemical Code 115501
1,3-Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione
BRN 0882348
DTXSID8035217
HSDB 7488
1,3-Di(hydroxymethyl)-5,5-dimethylhydantoin
DTXCID6015217
1,3-DIMETHYLOL-5,5-DIMETHYL-HYDANTOIN
EC 229-222-8
Hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
DMDM HYDANTOIN (II)
DMDM HYDANTOIN [II]
Dantoguard
Dantion DMDMH 55
DMDM HYDANTION
DDAC0.6%
DDAC0.15%
n,n'-dimethylol-5,5-dimethylhydantoin
USEPA/OPP Pesticide Code: 115501
1,3 BIS(HYDROXYMETHYL)-5,5-DIMETHYLHYDANTOINDIMETHYLHYDANTOIN
229-222-8
1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
Dimethyloldimethyl hydantoin
2,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
dimethyloldimethylhydantoin
MFCD00467199
1,3-DIHYDROXYMETHYL-5,5-DIMETHYLHYDANTOIN
SCHEMBL69185
DMDM HYDANTION [VANDF]
DMDM HYDANTOIN [VANDF]
Tox21_303842
AKOS006345746
CS-W021276
FD31768
NCGC00356947-01
AS-10924
SY101650
CAS-6440-58-0
DMDM hydantoin, 50% min aqueous solution
NS00007210
H11751
Q5205613
1,3-DIMETHYLOL-5,5-DIMETHYLHYDANTOIN [HSDB]
1,3-Bis (hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
1,3 BIS(HYDROXYMETHYL)-5,5- DIMETHYLHYDANTOINDIMETHYLHYDANTOIN
1 pound not3-Bis(hydroxymethyl)-5 pound not5-dimethylimidazolidine-2 pound not4-dione