Forskolin | Solubility of Things

Identification

Molecular formula

C₂₂H₃₄O₇

CAS number

66575-29-9

IUPAC name

[1,3-diacetoxy-7,8-dimethyl-7-(3-methylpenta-2,4-dienyl)-1,3,5,6,6a,8,9,10-octahydrobenzo[d]isobenzofuran-5-yl] 4-hydroxy-3-methoxy-benzoate

State

At room temperature, forskolin is typically found in a solid state as a crystalline powder. Its stability in this form allows for a relatively long shelf life when stored under appropriate conditions to avoid moisture and light exposure.

Melting point (Celsius)

233.00

Melting point (Kelvin)

506.20

Boiling point (Celsius)

586.10

Boiling point (Kelvin)

859.20

General information

Molecular weight

410.51g/mol

Molar mass

410.4890g/mol

Density

1.3000g/cm³

Appearence

Forskolin appears as an off-white or slightly yellow crystalline powder. It is often stored in a dry state and may exhibit a range of particle sizes depending on its form. The powder is noted for its crystalline texture.

Comment on solubility

Solubility of [1,3-diacetoxy-7,8-dimethyl-7-(3-methylpenta-2,4-dienyl)-1,3,5,6,6a,8,9,10-octahydrobenzo[d]isobenzofuran-5-yl] 4-hydroxy-3-methoxy-benzoate

The solubility of chemical compounds is often influenced by their molecular structure, functional groups, and interactions with solvents. In the case of C₂₂H₃₄O₇, the combination of several functional groups suggests varying degrees of solubility in different solvents.

Factors Affecting Solubility

Polarity: This compound features multiple hydroxyl and methoxy groups, which can enhance solubility in polar solvents like water.
Size and Structure: The large, complex molecular structure may hinder its solubility due to steric factors.
Hydrophobic Regions: The presence of hydrophobic moieties could reduce solubility in polar solvents while favoring solubility in non-polar organic solvents.

In summary, one could expect the following:

Good solubility in polar solvents due to hydrophilic groups.
Lower solubility in water due to the bulky structure and hydrophobic components.
Increased solubility in organic solvents such as ethanol or dichloromethane.

As a result, the solubility characteristic of this compound is quite dependent on the solvent used, making it a versatile candidate for various applications in chemical formulation.

Interesting facts

Interesting Facts about [1,3-Diacetoxy-7,8-dimethyl-7-(3-methylpenta-2,4-dienyl)-1,3,5,6,6a,8,9,10-octahydrobenzo[d]isobenzofuran-5-yl] 4-hydroxy-3-methoxy-benzoate

This compound is a fascinating molecule that highlights the complexity and diversity found in organic chemistry. Its structure demonstrates a variety of functional groups and a multi-ring architecture that contributes to its unique chemical properties.

Key Highlights:

Structure Complexity: The presence of multiple acetoxy and methoxy groups illustrates the synthetic versatility of organic compounds.
Natural Product Inspiration: Compounds like this can be inspired by or derived from natural products, which are often sources for pharmaceuticals and other biologically active substances.
Reactivity Potential: The double bonds present in the molecule suggest potential sites for reactivity, which could be exploited for further chemical transformations.
Applications: Structures similar to this have often been studied for their potential in medicinal chemistry, particularly in the discovery of new drugs.

As a chemistry student, one might find it exciting to explore the synthesis of such compounds, delving into techniques such as functional group interconversions or ring-closing reactions. Moreover, the study of compounds with such intricate structures emphasizes the importance of understanding stereochemistry and molecular interactions.

In conclusion, the evaluation of [1,3-diacetoxy-7,8-dimethyl-7-(3-methylpenta-2,4-dienyl)-1,3,5,6,6a,8,9,10-octahydrobenzo[d]isobenzofuran-5-yl] 4-hydroxy-3-methoxy-benzoate not only showcases the beauty of organic synthesis but also opens pathways for exciting research possibilities in fields like medicinal and synthetic chemistry.