Skip to main content

1,3-Difluorobenzene

ADVERTISEMENT
Identification
Molecular formula
C6H4F2
CAS number
372-18-9
IUPAC name
1,3-difluorobenzene
State
State

At room temperature, 1,3-Difluorobenzene is in a liquid state. It remains stable as a liquid under standard conditions, with relatively low volatility compared to lighter aromatic compounds.

Melting point (Celsius)
-43.00
Melting point (Kelvin)
230.15
Boiling point (Celsius)
85.60
Boiling point (Kelvin)
358.75
General information
Molecular weight
114.10g/mol
Molar mass
114.1020g/mol
Density
1.1980g/cm3
Appearence

1,3-Difluorobenzene is a clear, colorless liquid. It is characterized by its aromatic odor, typical of benzene derivatives. The compound is transparent and often handled in environments where glare or ambient light allows for visualization of its liquid state. It does not form crystals at room temperature, maintaining a fluid appearance.

Comment on solubility

Solubility of 1,3-Difluorobenzene

1,3-Difluorobenzene, with the chemical formula C6H4F2, exhibits certain unique solubility characteristics influenced by its molecular structure.

Key points regarding its solubility include:

  • Polar and Nonpolar Solvent Compatibility: Being a fluoro-substituted aromatic hydrocarbon, 1,3-difluorobenzene showcases moderate solubility in organic solvents, such as:
    • Chloroform
    • Ethanol
    • Acetone
    • Ether
    • Benzene
  • Water Solubility: It is generally considered to have a low solubility in water, which is characteristic of many nonpolar organic compounds.
  • Temperature Dependence: The solubility can also vary with temperature, making it pertinent to analyze conditions during use or experimentation.

In summary, while 1,3-difluorobenzene is soluble in a variety of organic solvents, its limited solubility in water highlights the intricacies of solvent interactions with this compound. The balance of polar and nonpolar characteristics plays a vital role in determining its behavior in different chemical environments.

Interesting facts

Interesting Facts about 1,3-Difluorobenzene

1,3-Difluorobenzene is a fascinating compound that belongs to the family of halogenated benzenes. This compound is particularly notable for the following reasons:

  • Structure and Isomerism: The presence of two fluorine atoms at the 1 and 3 positions on the benzene ring gives rise to its ortho substitution pattern, which influences its chemical properties and reactivity. This isomerism is significant, as ortho, meta, and para substitutions lead to distinct properties and applications.
  • Reactivity: 1,3-Difluorobenzene is known for its relatively stable nature compared to other fluorinated benzenes, owing to the strong C-F bond. However, under certain conditions, it can participate in various electrophilic substitution reactions, making it useful in synthetic organic chemistry.
  • Applications: This compound has been utilized as a solvent and an intermediate in the synthesis of pharmaceuticals and agrochemicals. It also finds applications in materials science due to its unique electronic properties.
  • Environmental Impact: While fluorinated compounds can be stable and resistant to degradation, their environmental impact is a matter of concern. Understanding the fate of such compounds in the environment is crucial for developing sustainable practices.
  • Fluorine Chemistry: The study of fluorinated compounds like 1,3-difluorobenzene highlights the significance of fluorine in enhancing the biological activity and stability of various molecules. This characteristic is essential in drug design and development.

In summary, 1,3-difluorobenzene serves as a prime example of how small changes in molecular structure can have profound effects on chemical behavior and application. As researchers continue to explore its potentials, this compound remains a valuable subject in both organic chemistry and industrial applications.

Synonyms
1,3-DIFLUOROBENZENE
372-18-9
m-Difluorobenzene
Benzene, 1,3-difluoro-
2,4-difluorobenzene
Benzene, m-difluoro-
meta-Difluorobenzene
1,3-Difluorbenzol
UNII-VO3C26WOC2
EINECS 206-746-5
VO3C26WOC2
NSC 10285
MFCD00000327
NSC-10285
1,3-BISFLUOROBENZENE
CHEBI:38584
DTXSID50190682
1,3difluorobenzene
1,3 difluorobenzene
2,6-difluorobenzene
Benzene,3-difluoro-
1,3-difluoro-benzene
WLN: FR CF
SCHEMBL13329
1,3-Difluorobenzene, >=99%
DTXCID90113173
NSC10285
AKOS000119939
FD31678
PS-11965
DB-019928
DB-049081
D1626
NS00042186
EN300-19453
Q27117910
F0001-1068